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Secret tunnels used by cancer cells can be exploited to deliver drug therapies, suggests new study

A new discovery published in the Nov. 2015 issue of The FASEB Journal shows that cancer cells use previously unknown channels to communicate with one another and with adjacent non-cancerous cells.

3 Nov 2015

Inhibiting key enzyme pathways decreases inflammation and frailty in aged mice

Chronic inflammation, closely associated with frailty and age-related diseases, is a hallmark of aging. Mayo Clinic researchers have discovered that inhibiting key enzyme pathways reduces inflammation in human cells in culture dishes and decreases inflammation and frailty in aged mice.

3 Nov 2015

Discovery offers promising alternative to current therapies for AMD and ROP

A research team led by scientists at Beth Israel Deaconess Medical Center and the University of New Mexico School of Medicine has identified a small molecule that treats animal models of aged macular degeneration (AMD) and retinopathy of prematurity (ROP) by preventing the overgrowth of blood vessels that are characteristic of these two retinal diseases.

3 Nov 2015

UAB study aims to provide improved care related to reproductive health of women with CF

For University of Alabama at Birmingham School of Nursing Assistant Professor Sigrid Ladores, Ph.D., investigating reproductive health concerns in adolescents and young adults with chronic illnesses, particularly those with cystic fibrosis, is not just a profession, it is a passion.

3 Nov 2015

Griffith University uncovers first 3-D image of protein linked to cancer spread

Griffith University's Institute for Glycomics has made scientific history by determining the first three-dimensional image of a protein linked to the spread of cancer.

3 Nov 2015

Researchers identify tumor suppressor genes that drive subset of melanomas

Of the hundreds of genes that can be mutated in a single case of melanoma, only a handful may be true "drivers" of cancer. In research that appeared today in Nature Genetics, a Weizmann Institute of Science team has now revealed one of the drivers of a particularly deadly subset of melanomas - one that is still seeing a rise in new cases. This gene is a newly identified member of a group of genes called tumor suppressor genes.

3 Nov 2015

Diet rich in soy protein and isoflavones can protect menopausal women from osteoporosis

Eating a diet rich in both soy protein and isoflavones can protect menopausal women from bone weakening and osteoporosis, according to the results of a preliminary study presented today at the Society for Endocrinology annual conference in Edinburgh.

2 Nov 2015

Researchers develop cancer-killing 'grenades’

Researchers have developed cancer drug-packed 'grenades' armed with heat sensitive triggers, allowing for treatment to be targeted directly at tumours, according to two studies due to be presented at the National Cancer Research Institute (NCRI) Cancer Conference in Liverpool.

31 Oct 2015

Sun Valley Juice ordered by FDA to cease all operations

The U.S. Food and Drug Administration has ordered Sun Valley Juice Company of Ketchum, Idaho, to stop receiving, processing, preparing, packing, holding, and distributing juice until the agency determines that the company is in compliance with laws and regulations applicable to producing food that is safe.

31 Oct 2015

New method helps study chaotic genomes of cancer cells more precisely than ever before

Scientists of the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg have developed a method for analysing the genome of cancer cells more precisely than ever before.

31 Oct 2015

Rotation model provides explanation of ligand activation mechanism of dimeric receptors

"This 'rotation model', which made the cover of BioEssays, represents a true paradigm shift in the membrane receptor field," stated Prof. Pierre De Meyts, a renowned researcher of insulin and receptor binding for almost half a century and one of the reviewers of the paper by Prof. Ichiro Maruyama, the head of the Information Processing Biology Unit at Okinawa Institute of Science and Technology Graduate University.

31 Oct 2015

New practice guidelines for compulsory treatment of mentally ill patients

In psychiatric wards, patients used to be medicated indiscriminately against their will for decades if doctors thought it necessary. It was only after a Federal Constitution Court ruling a few years ago that patient autonomy has been strengthened.

31 Oct 2015

UCSD researchers develop new computational strategy to find tumor-shrinking molecules

Patients with glioblastoma, a type of malignant brain tumor, usually survive fewer than 15 months following diagnosis. Since there are no effective treatments for the deadly disease, University of California, San Diego researchers developed a new computational strategy to search for molecules that could be developed into glioblastoma drugs. In mouse models of human glioblastoma, one molecule they found shrank the average tumor size by half.

31 Oct 2015

Blocking calcium-signaling pathway could inhibit Ebola virus and other sources of deadly infections

The Ebola virus acts fast. The course of infection, from exposure to recovery, or death, can take as little as two weeks. That may not leave enough time for the immune system to mount an effective response.

31 Oct 2015

RNA profiles of tumor-educated platelets may diagnose cancer, identify potential therapeutic approaches

Analysis of tumor RNA carried in platelets - blood components best known for their role in clotting - may prove to be more useful than other "liquid biopsy" technologies for diagnosing cancer and determining its primary location and potential therapeutic approaches.

31 Oct 2015

Chronic pain sufferers may benefit from therapy to help them sleep better, study finds

Research conducted at the University of Warwick indicates that chronic pain sufferers could benefit from therapy to help them sleep better.

31 Oct 2015

Researchers discover key regulator that impacts survival of lymphoma patients

An important regulator that controls the ability of tumour cells to hide from the immune system in lymphoma patients, making them unlikely to respond to standard treatment, has been discovered by scientists at the University of Oxford.

31 Oct 2015

ISCT launches publication and reference guide on Use of Unproven Cellular Therapies

The International Society for Cellular Therapy, the global society of clinicians, researchers, regulators, technologists, and industry partners dedicated to the translation of cellular therapy into safe and effective therapies to improve patients’ lives, today announces the launch of its publication and reference guide on the Use of Unproven Cellular Therapies.

31 Oct 2015

Radiocarbon method proves Cameroon’s environment is contaminated with synthetic opioid

Tramadol, a synthetic opioid component of the painkiller tramal, was surprisingly identified in 2013 as a natural product of Sarcocephalus latifolia, a tree found in Cameroon.

31 Oct 2015

Alexza plans to reacquire U.S. rights for ADASUVE (loxapine) inhalation powder from Teva

Alexza Pharmaceuticals, Inc. announced today that it plans to reacquire the U.S. rights for ADASUVE (loxapine) inhalation powder from Teva Pharmaceuticals USA, Inc., a subsidiary of Teva Pharmaceutical Industries Ltd., with an estimated target completion date of January 1, 2016.

31 Oct 2015

Drugs News and Research

Secret tunnels used by cancer cells can be exploited to deliver drug therapies, suggests new study

Inhibiting key enzyme pathways decreases inflammation and frailty in aged mice

Discovery offers promising alternative to current therapies for AMD and ROP

UAB study aims to provide improved care related to reproductive health of women with CF

Griffith University uncovers first 3-D image of protein linked to cancer spread

Researchers identify tumor suppressor genes that drive subset of melanomas

Diet rich in soy protein and isoflavones can protect menopausal women from osteoporosis

Researchers develop cancer-killing 'grenades’

Sun Valley Juice ordered by FDA to cease all operations

New method helps study chaotic genomes of cancer cells more precisely than ever before

Rotation model provides explanation of ligand activation mechanism of dimeric receptors

New practice guidelines for compulsory treatment of mentally ill patients

UCSD researchers develop new computational strategy to find tumor-shrinking molecules

Blocking calcium-signaling pathway could inhibit Ebola virus and other sources of deadly infections

RNA profiles of tumor-educated platelets may diagnose cancer, identify potential therapeutic approaches

Chronic pain sufferers may benefit from therapy to help them sleep better, study finds

Researchers discover key regulator that impacts survival of lymphoma patients

ISCT launches publication and reference guide on Use of Unproven Cellular Therapies

Radiocarbon method proves Cameroon’s environment is contaminated with synthetic opioid

Alexza plans to reacquire U.S. rights for ADASUVE (loxapine) inhalation powder from Teva

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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