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Stem cell gene linked to a portion of one of the most common childhood brain cancers

Scientists at Johns Hopkins have linked a stem-cell gene to a portion of one of the most common childhood brain cancers, opening the door to tailored therapies that block the gene's tumor-promoting ability.

10 Nov 2004

Researchers have developed a new algorithm that can lead to more accurate detection of cancer genes

Researchers at New York University's Courant Institute of Mathematical Sciences have developed a new algorithm that can lead to more accurate detection of cancer genes than previous versions.

8 Nov 2004

New study to determine whether natural tomato oil may reverse or delay progression of prostate cancer

Lycopene, an antioxidant commonly found in tomatoes and tomato-based products, is commonly perceived to reduce the risk of developing prostate cancer.

8 Nov 2004

MRI technique for measuring blood volume helps distinguish between abscesses and tumors in the brain

Dynamic susceptibility contrast (DSC) MRI allows physicians to differentiate between cerebral abscesses—inflamed areas in the brain caused by infection—and malignant brain tumors without surgery, says a new preliminary study by researchers from Duke University Medical Center in Durham, NC.

8 Nov 2004

Testosterone may impede immunity

Decreasing testosterone boosts immunity because testosterone helps control T-lymphocytes, the attack cells of the immune system, according to Mayo Clinic-led research in laboratory animals.

8 Nov 2004

Link between immune protein and longer survival in melanoma patients

Immune responses to prevent or delay the spread of melanoma, a deadly form of skin cancer, are more likely to prolong survival in patients if their immune cells carry a special kind of marker on the surface, according to a team of researchers at the University of Virginia Health System.

5 Nov 2004

Autophagy may even provide a clue to the mythical fountain of youth

The cells of higher organisms have an internal mechanism for chewing up and recycling parts of themselves, particularly in times of stress, like starvation and disease. But nobody is quite sure yet whether this recently discovered process protects cells, or causes damage.

5 Nov 2004

Researchers have identified a protein that transports the essential nutrient boron into cells

Researchers at UT Southwestern Medical Center at Dallas have identified a protein that transports the essential nutrient boron into cells, where it is important for cell growth and bone development. The findings are in the Nov. 5 edition of the journal Molecular Cell and are online.

5 Nov 2004

Celebrex may one day be used to prevent and even treat breast tumors

The anti-inflammatory drug Celebrex, or celecoxib, reduces tumor mass by encouraging cell death and discouraging both cell proliferation and the sprouting of new blood vessels that feed growing tumors, according to a study reported in the November issue of Molecular Cancer Research.

5 Nov 2004

Cellular vehicle delivers drugs directly into cancer cells

Researchers at The University of Texas M. D. Anderson Cancer Center have perfected a delivery system for anticancer treatment that zeroes in on a tumor and becomes part of its supporting tissue.

4 Nov 2004

Sensor protein that identifies DNA breaks and activates the p53 cell-death program has been identified

DNA breaks from radiation, toxic chemicals, or other environmental causes occur routinely in cells and, unless promptly and properly repaired, can lead to cancer-causing mutations.

4 Nov 2004

STAT3 protein could lead to new ways to prevent skin cancer

Scientists at The University of Texas M. D. Anderson Cancer Center have identified a protein that serves as a master regulator of skin cancer - a finding that could lead to new ways to prevent skin cancer before it starts.

4 Nov 2004

FDA fast tracks investigational anti-cancer drug, phenoxodiol

Marshall Edwards today announced that the U.S. Food and Drug Administration (FDA) has granted the investigational anti-cancer drug, phenoxodiol, Fast Track status for its intended use in patients with recurrent ovarian cancer.

4 Nov 2004

The Bush Medicare Prescription has changed the identity of medical oncology

Under previous law, Medicare covered chemotherapy as well as radiation treatment for cancer patients, but did not pay for oral-dose anti-cancer drugs, unless they were available in both oral and injectable form.

4 Nov 2004

Less risks for patients participating in early phase cancer drug trials

The risk of treatment-related (toxic) death for cancer patients enrolled in phase 1 clinical trials had decreased significantly over the past 12 years (from 1991 to 2002), according to an article in the November 3 issue of JAMA.

3 Nov 2004

Analysis shows Remicade reduces pain associated with Crohn's disease

According to a new sub-analysis from the ACCENT I (A Crohn's disease Clinical trial Evaluating infliximab in a New long-term Treatment regimen) trial patients who received a three-dose induction regimen of Remicade experienced a significantly greater reduction in pain as assessed by four different pain questions after ten weeks, compared with patients who received a single dose of Remicade.

2 Nov 2004

Scientists have uncovered a significant new link in the chain of immune system events through which estrogen prevents bone loss

Through research in mice, the scientists discovered that an immune signaling molecule called type b transforming growth factor (TGFb) is responsible for a cascade of events that leads estrogen to prevent bone loss.

29 Oct 2004