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Taking blood pressure level before a patient enters O.R. may produce more accurate measurements

When a patient arrives in the operating room (O.R.) for surgery, one of the first things a physician will do is take his or her blood pressure, a "baseline" measurement used throughout the procedure. However, a new study presented at the ANESTHESIOLOGY 2015 annual meeting found blood pressure taken before the patient enters the O.R. may produce more accurate measurements and should be used to determine baseline blood pressure.

26 Oct 2015

New approaches to treating lung cancer patients in New Mexico

This year, more than 158,000 Americans are expected to die from lung cancer. That's a staggering number: it's more than all the deaths expected from breast, prostate, colon, rectum, bladder and skin cancers combined.

26 Oct 2015

Benzodiazepines and related drugs frequently used before and after diagnosis of Alzheimer's disease

Benzodiazepines and related drugs are initiated frequently in persons with Alzheimer's disease already before the diagnosis, and their use becomes even more common after the diagnosis, shows a recent study from the University of Eastern Finland.

26 Oct 2015

University of Manchester scientists identify brain mechanism that raises pain threshold

Scientists at The University of Manchester have shown for the first time that the numbers of opiate receptors in the brain increases to combat severe pain in arthritis sufferers.

26 Oct 2015

Novel method for examining small molecules may provide platform for new drug design

Most pharmaceutical drugs consist of tiny molecules, which target a class of proteins found on the surfaces of cell membranes. Studying these subtle interactions is essential for the design of effective drugs, but the task is extremely challenging.

26 Oct 2015

CHMP recommends approval of Cosentyx in Europe to treat patients with AS and PsA, says Novartis

Novartis announced today that the Committee for Medicinal Products for Human Use has recommended the approval of Cosentyx (secukinumab) in Europe to treat ankylosing spondylitis (AS) and psoriatic arthritis (PsA) patients.

26 Oct 2015

First computational method based on evolutionary principles developed to predict protein dynamics

Researchers from the Structural Biology Computational Group of the Spanish National Cancer Research Centre, led by Alfonso Valencia, in collaboration with a group headed by Francesco Gervasio at the University College London (UK), have developed the first computational method based on evolutionary principles to predict protein dynamics, which explains the changes in the shape or dimensional structure that they experience in order to interact with other compounds or speed up chemical reactions.

26 Oct 2015

Inhibiting JAK family of enzymes promotes rapid hair growth, new study finds

Inhibiting a family of enzymes inside hair follicles that are suspended in a resting state restores hair growth, a new study from researchers at Columbia University Medical Center has found.

26 Oct 2015

FDA approves Yondelis (trabectedin) for treatment of specific soft tissue sarcomas

The U.S. Food and Drug Administration today approved Yondelis (trabectedin), a chemotherapy, for the treatment of specific soft tissue sarcomas (STS) – liposarcoma and leiomyosarcoma – that cannot be removed by surgery (unresectable) or is advanced (metastatic).

24 Oct 2015

Strensiq approved for treatment of patients with juvenile-onset HPP

Today, the U.S. Food and Drug Administration approved Strensiq (asfotase alfa) as the first approved treatment for perinatal, infantile and juvenile-onset hypophosphatasia (HPP).

24 Oct 2015

Endocannabinoids can affect development of baby's pancreas

According to the latest research results from the Medical University of Vienna, endocannabinoids, cannabis-like substances produced by the body itself, can affect the development of a baby's pancreas. The study also highlights the importance of diet during pregnancy for the foetal pancreas to form.

23 Oct 2015

Spatial grid pattern in brain region is altered in young adults with Alzheimer's risk

Young adults with genetically increased Alzheimer's risk have altered activation patterns in a brain region that is crucial for spatial navigation.

23 Oct 2015

Stem cell biology and gene-editing techniques offer hope for kidney regeneration

Mini-kidney organoids have now been grown in a laboratory by using genome editing to re-create human kidney disease in petri dishes.

23 Oct 2015

Amgen's IMLYGIC receives positive opinion from CHMP for treatment of melanoma

Amgen today announced that the Committee for Medicinal Products for Human Use, the scientific committee of the European Medicines Agency, has adopted a positive opinion recommending that IMLYGIC (talimogene laherparepvec) be granted approval for the treatment of adults with unresectable melanoma that is regionally or distantly metastatic (Stage IIIB, IIIC and IVM1a) with no bone, brain, lung or other visceral disease.

23 Oct 2015

Discovery may lead to development of cell-based regenerative therapy to restore thyroid function

A discovery made by investigators from Beth Israel Deaconess Medical Center and the Boston University School of Medicine may help lead to the development of a cell-based regenerative therapy which could be used to restore thyroid function in patients with cancer who have had their thyroids surgically removed and children born with congenital hypothyroidism.

23 Oct 2015

Drug engineered from bananas could fight off wide range of viruses

A banana a day may not keep the doctor away, but a substance originally found in bananas and carefully edited by scientists could someday fight off a wide range of viruses, new research suggests.

23 Oct 2015

New drug delivery method could be used to target cancer, tuberculosis

Scientists have designed a novel method for improving the delivery of therapeutic molecules into diseased cells such as those found in cancer and tuberculosis.

23 Oct 2015

Medlab granted ethics approval to begin human trials using nanotechnology delivery platform

Sydney-based, ASX listed, biopharmaceutical company, Medlab Clinical Ltd has been granted ethics approval to progress to two separate human trials using its nanotechnology delivery platform.

23 Oct 2015

CDC publishes reports on infectious and noninfectious diseases

Beginning with the Oct. 23, 2015, Supplements to Morbidity and Mortality Weekly Report (MMWR), CDC will publish the summaries of all notifiable conditions – infectious and noninfectious – at the same time.

23 Oct 2015

New combination treatment approved by FDA for metastatic pancreatic cancer

The U.S. Food and Drug Administration today approved Onivyde (irinotecan liposome injection), in combination with fluorouracil and leucovorin, to treat patients with advanced (metastatic) pancreatic cancer who have been previously treated with gemcitabine-based chemotherapy.

23 Oct 2015

Drugs News and Research

Taking blood pressure level before a patient enters O.R. may produce more accurate measurements

New approaches to treating lung cancer patients in New Mexico

Benzodiazepines and related drugs frequently used before and after diagnosis of Alzheimer's disease

University of Manchester scientists identify brain mechanism that raises pain threshold

Novel method for examining small molecules may provide platform for new drug design

CHMP recommends approval of Cosentyx in Europe to treat patients with AS and PsA, says Novartis

First computational method based on evolutionary principles developed to predict protein dynamics

Inhibiting JAK family of enzymes promotes rapid hair growth, new study finds

FDA approves Yondelis (trabectedin) for treatment of specific soft tissue sarcomas

Strensiq approved for treatment of patients with juvenile-onset HPP

Endocannabinoids can affect development of baby's pancreas

Spatial grid pattern in brain region is altered in young adults with Alzheimer's risk

Stem cell biology and gene-editing techniques offer hope for kidney regeneration

Amgen's IMLYGIC receives positive opinion from CHMP for treatment of melanoma

Discovery may lead to development of cell-based regenerative therapy to restore thyroid function

Drug engineered from bananas could fight off wide range of viruses

New drug delivery method could be used to target cancer, tuberculosis

Medlab granted ethics approval to begin human trials using nanotechnology delivery platform

CDC publishes reports on infectious and noninfectious diseases

New combination treatment approved by FDA for metastatic pancreatic cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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