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Scientist develops new method for identifying proteins to build new biologics

A University of Toronto scientist has developed a new method for identifying the raw ingredients necessary to build 'biologics', a powerful class of medications that has revolutionized treatment of diseases like rheumatoid arthritis and some cancers.

22 Jul 2016

New protein may help scientists understand role of Abeta in Alzheimer's disease

A new protein which will help scientists to understand why nerve cells die in people with Alzheimer's disease has been designed in a University of Sussex laboratory.

22 Jul 2016

Scientists design and construct 10 large protein icosahedra to improve drug delivery

Using novel computational and biochemical approaches, scientists have accurately designed and built from scratch 10 large protein icosahedra--polyhedra with 20 faces--similar to viral capsids that carry viral DNA.

22 Jul 2016

New study identifies alternative route for tuberculosis infection

Researchers from UT Southwestern Medical Center have identified a new way that tuberculosis bacteria get into the body, revealing a potential therapeutic angle to explore.

22 Jul 2016

Researchers unveil engineered protein to suppress cancer-promoting message within cells

Over a century of research has shined light on the once-murky innards of our cells, from the genes that serve as our "blueprints" to the proteins and other molecules that are our cellular taskmasters.

22 Jul 2016

Researchers identify important therapeutic target for small cell lung cancer

UT Southwestern Medical Center researchers have identified a protein termed ASCL1 that is essential to the development of small cell lung cancer and that, when deleted in the lungs of mice, prevents the cancer from forming.

22 Jul 2016

Key gene controls ability of adult stem cells to regenerate muscle after injury, study finds

A key gene enables the repair of injured muscle throughout life. This is the finding of a study in mice led by researchers at NYU Langone Medical Center and the University of Colorado at Boulder, and published online July 21 in Cell Reports.

21 Jul 2016

Study highlights role of BCL11A gene in intellectual disability syndrome

Scientists at the Wellcome Trust Sanger Institute and Max Planck Institute for Psycholinguistics have found a gene responsible for an intellectual disability disorder and proven how it works.

21 Jul 2016

Huntington's disease monkey model embodies full array of symptoms similar to human patients

Transgenic Huntington's disease monkeys display a full spectrum of symptoms resembling the human disease, ranging from motor problems and neurodegeneration to emotional dysregulation and immune system changes, scientists at Yerkes National Primate Research Center, Emory University report.

21 Jul 2016

Combining ART with immune-enhancing treatment may destabilize HIV reservoirs

Although antiretroviral therapy (ART) can reduce the amount of HIV in the blood to an undetectable level in most chronically infected people, it cannot eliminate reservoirs of HIV that persist in latently infected immune cells.

21 Jul 2016

Neutrons key to discovering new HIV drugs? An interview with Dr Matthew Blakeley

Neutron crystallography allows us to determine the three-dimensional structures of biological macromolecules, such as proteins, by means of the diffraction of neutrons from the regularly spaced atoms of a crystal.

21 Jul 2016

GSK and University of Leicester team up to develop novel drugs to treat blood cancer

A collaboration between the University of Leicester and global pharmaceutical company GlaxoSmithKline has been established to discover and develop novel medicines to treat aggressive forms of blood cancer.

21 Jul 2016

Researchers identify unique mechanism to suppress colorectal cancer tumors in mice

A new scientific study has identified why colorectal cancer cells depend on a specific nutrient, and a way to starve them of it. Over one million men and women are living with colorectal cancer in the United States.

21 Jul 2016

TSRI study reveals new approach to intervene in deadly disease

In a new study, scientists at The Scripps Research Institute have identified drug candidates that can boost a cell's ability to catch the "typos" in protein production that can cause a deadly disease called amyloidosis.

From Paxman 21 Jul 2016

Penn researchers develop plant-based oral vaccine booster

Jonas Salk created a vaccine against polio that has been used since 1955; Albert Sabin created another version that has been on the market since 1961. Together, these two vaccines have nearly eliminated polio from the face of the earth.

20 Jul 2016

Enhancers can boost frequency of transcriptional bursting, study shows

A new study by researchers at Princeton University suggests that sporadic bursts of gene activity may be important features of genetic regulation rather than just occasional mishaps.

20 Jul 2016

Breakthrough research shows cellular stress could be key to variety of birth defects

For the first time, scientists believe they've discovered a cause of multiple types of birth defects triggered by environmental stresses.

20 Jul 2016

Researchers discover novel neuroprotection strategies to slow progression of Parkinson's disease

Using a robust model for Parkinson's disease, University of Alabama at Birmingham researchers and colleagues have discovered an interaction in neurons that contributes to Parkinson's disease, and they have shown that drugs now under development may block the process.

20 Jul 2016

Study offers new hope for preventing chronic lung disease in premature infants

By triggering a process called autophagy -- in which cells literally engulf their own insides --researchers from Drexel University and Yale University were able to decrease lung injury in mice that were exposed to high concentrations of oxygen.

20 Jul 2016

Home cooked food for young children not always better than readymade meals

Home cooked meals specifically designed for infants and young children, are not always better than commercially available baby foods.

20 Jul 2016

Protein C News and Research

Scientist develops new method for identifying proteins to build new biologics

New protein may help scientists understand role of Abeta in Alzheimer's disease

Scientists design and construct 10 large protein icosahedra to improve drug delivery

New study identifies alternative route for tuberculosis infection

Researchers unveil engineered protein to suppress cancer-promoting message within cells

Researchers identify important therapeutic target for small cell lung cancer

Key gene controls ability of adult stem cells to regenerate muscle after injury, study finds

Study highlights role of BCL11A gene in intellectual disability syndrome

Huntington's disease monkey model embodies full array of symptoms similar to human patients

Combining ART with immune-enhancing treatment may destabilize HIV reservoirs

Neutrons key to discovering new HIV drugs? An interview with Dr Matthew Blakeley

GSK and University of Leicester team up to develop novel drugs to treat blood cancer

Researchers identify unique mechanism to suppress colorectal cancer tumors in mice

TSRI study reveals new approach to intervene in deadly disease

Penn researchers develop plant-based oral vaccine booster

Enhancers can boost frequency of transcriptional bursting, study shows

Breakthrough research shows cellular stress could be key to variety of birth defects

Researchers discover novel neuroprotection strategies to slow progression of Parkinson's disease

Study offers new hope for preventing chronic lung disease in premature infants

Home cooked food for young children not always better than readymade meals

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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