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Safer, more effective therapies could help fight the obesity epidemic

Novel obesity treatments such as modulation of the gut microbiome and gene therapy are underutilized and could help fight the obesity epidemic, according to a new manuscript published in the Endocrine Society's journal, Endocrine Reviews.

26 Oct 2021

Study discloses molecular mechanism of oligodendrocyte myelination by osteocalcin in the CNS

Osteocalcin (OCN) is a multifunctional bone-derived hormone that modulates numerous physiological activities. OCN can cross the blood brain barrier (BBB) and thus play critical roles in neuronal and brain development.

25 Oct 2021

New AI-based tool helps clinicians understand and better predict adverse effects of COVID-19

The symptoms and side effects of Covid-19 are scattered across a diagnostic spectrum. Some patients are asymptomatic or experience a mild immune response, while others report significant long-term illnesses, lasting complications, or suffer fatal outcomes.

22 Oct 2021

$Extra dairy intake lowers risk of falls and fractures among older adults in residential care$

Extra dairy intake lowers risk of falls and fractures among older adults in residential care

Increasing intake of foods rich in calcium and protein such as milk, yogurt, and cheese, reduces falls and fractures in older adults living in residential care, finds a randomized controlled trial published by The BMJ today.

21 Oct 2021

Interferon treatment coupled with bone marrow transplant reduces risk of leukemia recurrence

Researchers at the University of Michigan Health Rogel Cancer Center have identified a drug that, when given along with a bone marrow transplant, drops the risk of leukemia recurring by 20% among the high-risk patients.

21 Oct 2021

Discovery could lead to new treatments for axial spondyloarthritis

In a paper published today in the journal Science Translational Medicine, researchers at the Schroeder Arthritis Institute, part of University Health Network in Toronto, have made a discovery that could lead to new treatments for axial spondyloarthritis (SpA), a painful and debilitating form of arthritis which affects 1-2% of Canadians and causes inflammation in the spine, joints, eyes, gut and skin.

20 Oct 2021

Washington University receives $7.5 million to support NIH's research on senescent cells

Washington University School of Medicine in St. Louis is joining the National Institutes of Health's new research network focused on the study of senescent cells, a rare and important population of cells that is difficult to study but vital for understanding aging and the diseases of aging, including cancer and neurodegeneration.

20 Oct 2021

New findings may help widen therapeutic interventions for B-cell acute lymphoblastic leukemia

A retrospective study led by Northwestern Medicine investigators found that the chimeric antigen receptor (CAR) T-cell immunotherapy drug tisagenlecleucel demonstrated safety and efficacy in pediatric patients with relapsed and refractory B-cell acute lymphoblastic leukemia (B-cell ALL), even when the drug doesn't meet the FDA's strict manufacturing standards.

19 Oct 2021

Researchers report long-lasting effects of gene therapy in children with deadly immune disorder

Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder.

18 Oct 2021

RUDN study reveals macrophage dynamics in the regenerating liver after resection

RUDN University discovered the features of liver macrophages activation during its regeneration. In future, it can be used to develop new treatment methods for liver cirrhosis. The results are published in the Biomedicine.

15 Oct 2021

New nutrient profiling system assesses the healthfulness of foods

A scientific team at the Friedman School of Nutrition Science and Policy at Tufts has developed a new tool to help consumers, food companies, restaurants, and cafeterias choose and produce healthier foods and officials to make sound public nutrition policy.

14 Oct 2021

New discovery suggests potential treatment target for osteoporosis and rheumatoid arthritis

A new discovery about osteoporosis suggests a potential treatment target for that brittle-bone disease and for bone loss from rheumatoid arthritis.

14 Oct 2021

SARS-CoV-2 induces tissue immune memory

A new study reports that the SARS-CoV-2 induces protective tissue memory that includes both humoral and cellular elements to protect specific tissue sites.

14 Oct 2021

Study shows how tissue-derived T cells can damage other organs in stem cell transplant patients

More than 40,000 allogeneic hematopoietic stem cell transplants are carried out worldwide every year, mostly for patients suffering from leukemia or other diseases of the hematopoietic system.

13 Oct 2021

Anti-rheumatic drug as a potential candidate for treating COVID-19

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produces inflammatory cytokine storms. But an FDA-approved anti-rheumatic drug, Auranofin, used to treat autoimmune and infectious diseases, may also help serve as an antiviral treatment for COVID-19 infection.

13 Oct 2021

Novel surgical procedure for intractable canalicular obstruction

Under normal conditions, tears in the eyes are drained into the lacrimal sac through small openings called the upper and lower puncta located at the inner corner of the eye (called medial canthus).

12 Oct 2021

Long stays in space appear to cause brain damage

Spending a long time in space appears to cause brain damage. This is shown by a study of five Russian cosmonauts who had stayed on the International Space Station.

12 Oct 2021

Vaccinated children induced significantly higher antibody titers than naturally SARS-CoV-2 infected children

A recent preprint discusses the antibody response to the nucleic acid vaccines against SARS-CoV-2 when administered to children aged 7-11 years.

12 Oct 2021

$Researchers identify a stem cell population with enhanced fracture healing and differentiation abilities$

Researchers identify a stem cell population with enhanced fracture healing and differentiation abilities

Mesenchymal stem cells (MSCs) are thought to have great potential in the field of regenerative medicine, which has the aim of restoring damaged tissues. However, not much was known about in vivo plasticity of them—until now.

8 Oct 2021

$'Fractionated' radiation therapy for spinal tumors helps prevent vertebral compression fractures$

'Fractionated' radiation therapy for spinal tumors helps prevent vertebral compression fractures

In an animal study published Oct. 1, 2021, in the International Journal of Radiation Oncology, Biology and Physics, Johns Hopkins Medicine researchers have provided evidence that treating spinal tumors with "fractionated" radiation therapy — doses given in a series of sessions rather than a single treatment — helps prevent vertebral compression fractures.

7 Oct 2021

Bone News and Research

Safer, more effective therapies could help fight the obesity epidemic

Study discloses molecular mechanism of oligodendrocyte myelination by osteocalcin in the CNS

New AI-based tool helps clinicians understand and better predict adverse effects of COVID-19

Extra dairy intake lowers risk of falls and fractures among older adults in residential care

Interferon treatment coupled with bone marrow transplant reduces risk of leukemia recurrence

Discovery could lead to new treatments for axial spondyloarthritis

Washington University receives $7.5 million to support NIH's research on senescent cells

New findings may help widen therapeutic interventions for B-cell acute lymphoblastic leukemia

Researchers report long-lasting effects of gene therapy in children with deadly immune disorder

RUDN study reveals macrophage dynamics in the regenerating liver after resection

New nutrient profiling system assesses the healthfulness of foods

New discovery suggests potential treatment target for osteoporosis and rheumatoid arthritis

SARS-CoV-2 induces tissue immune memory

Study shows how tissue-derived T cells can damage other organs in stem cell transplant patients

Anti-rheumatic drug as a potential candidate for treating COVID-19

Novel surgical procedure for intractable canalicular obstruction

Long stays in space appear to cause brain damage

Vaccinated children induced significantly higher antibody titers than naturally SARS-CoV-2 infected children

Researchers identify a stem cell population with enhanced fracture healing and differentiation abilities

'Fractionated' radiation therapy for spinal tumors helps prevent vertebral compression fractures

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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