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Study provide new insights into why cholestasis causes cognitive issues

Patients with cholestatic liver disease such as primary biliary cholangitis (PBC) can experience significant impairment of bile flow and may develop neurological symptoms including fatigue and cognitive decline.

6 Dec 2022

New study details the neuronal response to excessive aged-related iron accumulation

Iron (Fe) accumulates in the brain cortex with aging. A plethora of studies indicate that progressive iron accumulation in the substantia nigra (SN) in the aged human brain is a major risk factor for Parkinson's disease (PD) and other neurodegenerative diseases, but not everyone.

6 Dec 2022

Research reveals a novel viral strategy in modulating stress granule formation to promote virus infection

Researchers illustrated a novel strategy likely employed by viruses to promote infection.

6 Dec 2022

Does irritable bowel syndrome result from gravity?

New research discussed the hypothesis that irritable bowel syndrome (IBS) may result from gravity.

5 Dec 2022

Discovery offers an avenue for development of novel therapies for Chagas disease

Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, affects some 8 million people worldwide. More than a third develop severe heart or digestive problems with a heightened risk of death.

5 Dec 2022

Does air pollution reduce cognitive function over time?

Researchers examine available studies for correlations between declining cognitive function in childhood and adult life and air pollution.

4 Dec 2022

Study shows how ketamine administration starkly changes neuronal activity patterns in the brain

Ketamine, an established anesthetic and increasingly popular antidepressant, dramatically reorganizes activity in the brain, as if a switch had been flipped on its active circuits, according to a new study by Penn Medicine researchers.

1 Dec 2022

New evidence on the links between immune activation and neuroinflammation and Parkinson's disease

In this special supplement to the Journal of Parkinson's Disease, "The Immune System in Parkinson's Disease," experts highlight the latest research breakthroughs on the links between immune activation and neuroinflammation and Parkinson's disease (PD) and discuss the challenges and novel therapeutic strategies targeting the immune system with the hope of reducing or reversing neurodegeneration.

1 Dec 2022

Study implicates a specific type of brain cell as key player underlying the impact of stressors

More than 70% of adults will experience at least one traumatic experience, such as a life-threatening illness or accident, violent assault or natural disaster, in their lifetimes and nearly a third will experience four or more, according to global data.

1 Dec 2022

UTHealth Houston professor wins $3.5 million to study the mechanisms of brain receptors involved in neurological disorders

A five-year, nearly $3.5 million grant to study the mechanisms of brain receptors involved in neurological disorders such as learning disabilities has been awarded to Vasanthi Jayaraman, PhD, of UTHealth Houston by the National Institutes of Health.

1 Dec 2022

Hyperactivated brain cells following social trauma impair social reward and promote social avoidance

Past social trauma is encoded by a population of stress/threat-responsive brain cells that become hyperactivated during subsequent interaction with non-threatening social targets. As a consequence, previously rewarding social targets are now perceived as social threats, which promotes generalized social avoidance and impaired social reward processing that can contribute to psychiatric disorders, according to a study conducted by researchers at the Brain and Body Research Center at Mount Sinai and published November 30 in Nature.

30 Nov 2022

Study reveals key details of how DREADD technology highjacks neuronal activity

Understanding of how neuronal activity modulates brain function is a key first step towards creating more effective drugs to treat a variety of neuropsychiatric illnesses, including depression, anxiety, schizophrenia, substance abuse, epilepsy, and others.

30 Nov 2022

Unique scaffolding material shows significant promise in the treatment of spinal cord injury

Unique new material developed at University of Limerick in Ireland has shown significant promise in the treatment of spinal cord injury.

29 Nov 2022

New transcranial magnetic stimulation array can help stimulate deeper tissue within the brain

As a noninvasive neuromodulation method, transcranial magnetic stimulation (TMS) shows great potential to treat a range of mental and psychiatric diseases, including major depression.

29 Nov 2022

Georgia State researcher receives $1.93 million NIH award to study visual processing

Jordan Hamm, an assistant professor of neuroscience at Georgia State University, has received a five-year, $1.93 million award from the National Eye Institute at the National Institutes of Health.

28 Nov 2022

Study reveals a promising therapeutic target for Alzheimer's disease

In a recent search for gene variants associated with Alzheimer's disease (AD), several affected families showed a mutation in an enzyme called protein kinase C-alpha (PKCα). Family members with this mutation had AD; those without the mutation did not.

28 Nov 2022

Neurons News and Research

Study provide new insights into why cholestasis causes cognitive issues

New study details the neuronal response to excessive aged-related iron accumulation

Research reveals a novel viral strategy in modulating stress granule formation to promote virus infection

Does irritable bowel syndrome result from gravity?

Discovery offers an avenue for development of novel therapies for Chagas disease

Does air pollution reduce cognitive function over time?

Study shows how ketamine administration starkly changes neuronal activity patterns in the brain

New evidence on the links between immune activation and neuroinflammation and Parkinson's disease

Study implicates a specific type of brain cell as key player underlying the impact of stressors

UTHealth Houston professor wins $3.5 million to study the mechanisms of brain receptors involved in neurological disorders

Hyperactivated brain cells following social trauma impair social reward and promote social avoidance

Study reveals key details of how DREADD technology highjacks neuronal activity

Unique scaffolding material shows significant promise in the treatment of spinal cord injury

New transcranial magnetic stimulation array can help stimulate deeper tissue within the brain

Georgia State researcher receives $1.93 million NIH award to study visual processing

Study reveals a promising therapeutic target for Alzheimer's disease

Imaging brain activity deep in the cortex of freely moving mouse

Molecular and cellular similarities identified in the brains of SARS-CoV-2 and Alzheimer's disease patients

Possibility of the first fluid biomarker that reflects brain pathology in primary tauopathies

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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