Genetic News and Research

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Genzyme, Isis receive 2014 Partners in Progress Corporate Award for KYNAMRO injection

Genzyme, a Sanofi company, and Isis Pharmaceuticals Inc., today announced that they have received the 2014 Partners in Progress Corporate Award from NORD in recognition of KYNAMRO (mipomersen sodium) injection.

9 May 2014

Sildenafil may help boys suffering from muscular dystrophy disease

Drugs used to treat erectile dysfunction may be able to slow disease progression in boys who suffer from the muscle wasting disease Duchenne muscular dystrophy.

8 May 2014

TSRI scientists create bacteria with expanded DNA code

Scientists at The Scripps Research Institute have engineered a bacterium whose genetic material includes an added pair of DNA “letters,” or bases, not found in nature. The cells of this unique bacterium can replicate the unnatural DNA bases more or less normally, for as long as the molecular building blocks are supplied.

8 May 2014

Finding has implications for understanding cognitive decline in degenerative diseases

New research suggests that certain types of brain cells may be "picky eaters," seeming to prefer one specific energy source over others. The finding has implications for understanding the cognitive decline seen in aging and degenerative diseases such as Alzheimer's and multiple sclerosis.

8 May 2014

Genetic changes linked to altered default mode network in psychosis

Researchers have identified biological processes likely to underlie altered activity in the resting-state default mode network in patients with psychosis.

8 May 2014

NeoGenomics selects Aurora as primary partner for molecular testing

NeoGenomics, Inc., a leading provider of cancer-focused genetic and molecular testing services, announced today that it has been selected by Aurora Diagnostics to be its primary partner for molecular testing at each of Aurora's 19 specialized anatomic pathology laboratories in the United States.

8 May 2014

New technique expands number of functional cord blood stem cells for transplantation

Adults suffering from diseases such as leukemia, lymphoma, and other blood-related disorders may benefit from life-saving treatment commonly used in pediatric patients. Researchers at the Icahn School of Medicine at Mount Sinai have identified a new technique that causes cord blood (CB) stems cells to generate in greater numbers making them more useful in adult transplantation.

8 May 2014

Children who wheeze are at risk of developing damage that affect lung function

Children who wheeze are at risk of developing damage that will affect their lung function by the age of 6 years, according to researchers at CHU Sainte-Justine Hospital and the University of Montreal.

8 May 2014

First international molecular screening program at IMPAKT for metastatic breast cancer

While research has made great strides in recent decades to improve and significantly extend the lives of patients with early breast cancer, the needs of patients with advanced or metastatic disease have largely been ignored.

8 May 2014

Commonly used drug restores blood flow to oxygen-starved muscles of boys with muscular dystrophy

Cedars-Sinai Heart Institute researchers have found that a commonly prescribed drug restores blood flow to oxygen-starved muscles of boys with Duchenne muscular dystrophy, a genetic muscle-wasting disease that rarely is seen in girls but affects one in 3,500 male babies, profoundly shortening life expectancy. It is the most common fatal disease that affects children.

8 May 2014

Power of GWAS to detect human disease can be increased using statistical testing

The power of genome-wide association studies (GWAS) to detect genetic influences on human disease can be substantially increased using a statistical testing framework reported in the May issue of the journal GENETICS.

8 May 2014

Two young neuroscientists win CAN Young Investigator Awards for 2014

The Canadian Association for Neuroscience is proud to announce that Dr. Stephanie Borgland, from the Hotchkiss Brain Institute at University of Calgary, and Dr. Brian Chen, from the Centre for Research in Neuroscience at McGill University, are both winners of CAN Young Investigator Awards for 2014.

8 May 2014

Common drug may improve blood flow in muscles of boys with Duchenne muscular dystrophy

A drug typically prescribed for erectile dysfunction or increased pressure in the arteries may help improve blood flow in the muscles of boys with Duchenne muscular dystrophy, according to a study published in the May 7, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.

8 May 2014

Neuron-to-neuron communication plays essential role in development of synapses

A study has shown that a long-overlooked form of neuron-to-neuron communication called miniature neurotransmission plays an essential role in the development of synapses, the regions where nerve impulses are transmitted and received.

8 May 2014

Controlling low-density lipoprotein-cholesterol levels: an interview with Jay Edelberg, M.D., Sanofi and Bill Sasiela, Ph.D., Regeneron

Lipids, primarily cholesterol and triglycerides, come from two sources: what is naturally manufactured in the liver and what comes from the intestines through the diet.

From Sanofi 7 May 2014

New approach to detect chromosomal abnormalities without harm to mother or fetus

Chromosomal abnormalities that result in birth defects and genetic disorders like Down syndrome remain a significant health burden in the United States and throughout the world, with some current prenatal screening procedures invasive and a potential risk to mother and unborn child.

7 May 2014

TGen/George Mason create strategic research alliance to benefit patients with cancer, life-threatening illnesses

The Translational Genomics Research Institute (TGen) and George Mason University today announced the creation of a strategic research alliance to benefit patients with cancer and other life-threatening illnesses.

7 May 2014

New research focuses on using wheat fiber to lower cholesterol and prevent development of heart disease

The saying, "we are what we eat," has never been more true. Nutritionists increasingly emphasize that the nutrients in the foods we consume can potentially create health and reduce disease.

7 May 2014

NanoString receives license from Health Canada to market Prosigna Breast Cancer Prognostic Gene Signature Assay

NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, today announced that it has received a Class III Medical Device License from Health Canada, clearing the company to market its Prosigna Breast Cancer Prognostic Gene Signature Assay for assessing a woman's 10-year risk of distant recurrence and accurately identifying the intrinsic biologic subtype of the tumor.

From NanoString Technologies 7 May 2014

New molecular "clamps" offer powerful new tool for identifying individuals with increased risk of cancer

An international research team has built molecular "clamps" out of DNA that offer a powerful new tool for identifying individuals with an increased risk of cancer.

7 May 2014

Genetic News and Research

Genzyme, Isis receive 2014 Partners in Progress Corporate Award for KYNAMRO injection

Sildenafil may help boys suffering from muscular dystrophy disease

TSRI scientists create bacteria with expanded DNA code

Finding has implications for understanding cognitive decline in degenerative diseases

Genetic changes linked to altered default mode network in psychosis

NeoGenomics selects Aurora as primary partner for molecular testing

New technique expands number of functional cord blood stem cells for transplantation

Children who wheeze are at risk of developing damage that affect lung function

First international molecular screening program at IMPAKT for metastatic breast cancer

Commonly used drug restores blood flow to oxygen-starved muscles of boys with muscular dystrophy

Power of GWAS to detect human disease can be increased using statistical testing

Two young neuroscientists win CAN Young Investigator Awards for 2014

Common drug may improve blood flow in muscles of boys with Duchenne muscular dystrophy

Neuron-to-neuron communication plays essential role in development of synapses

Controlling low-density lipoprotein-cholesterol levels: an interview with Jay Edelberg, M.D., Sanofi and Bill Sasiela, Ph.D., Regeneron

New approach to detect chromosomal abnormalities without harm to mother or fetus

TGen/George Mason create strategic research alliance to benefit patients with cancer, life-threatening illnesses

New research focuses on using wheat fiber to lower cholesterol and prevent development of heart disease

NanoString receives license from Health Canada to market Prosigna Breast Cancer Prognostic Gene Signature Assay

New molecular "clamps" offer powerful new tool for identifying individuals with increased risk of cancer

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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