Genetic News and Research

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Research: Novel therapeutic approach to overcome chemoresistance in ovarian cancer

Inhibiting enzymes that cause changes in gene expression could decrease chemotherapy resistance in ovarian cancer patients, researchers at Georgia State University and the University of Georgia say.

5 May 2014

Researchers discover potential genetic variant that may make brains more resilient against Alzheimer's

Autopsies have revealed that some individuals develop the cellular changes indicative of Alzheimer's disease without ever showing clinical symptoms in their lifetime.

5 May 2014

DNA 'sat nav' allows direct access to homes of ancestors alive 1,000 years ago

Tracing where your DNA was formed over 1,000 years ago is now possible due to a revolutionary technique developed by a team of international scientists led by experts from the University of Sheffield.

2 May 2014

Johns Hopkins biochemists figure out HIV-fighting activity of enzyme

Johns Hopkins biochemists have figured out what is needed to activate and sustain the virus-fighting activity of an enzyme found in CD4+ T cells, the human immune cells infected by HIV. The discovery could launch a more effective strategy for preventing the spread of HIV in the body with drugs targeting this enzyme, they say.

2 May 2014

New hope for improved diagnosis of children with TB

A distinctive genetic 'signature' found in the blood of children with tuberculosis (TB) offers new hope for improved diagnosis of the disease.

2 May 2014

Isis Pharmaceuticals reports final data from ISIS-APOCIIIRx Phase 2 study in patients with FCS

Isis Pharmaceuticals, Inc. announced the final data from its Phase 2 study of ISIS-APOCIIIRx as a monotherapy in patients with familial chylomicronemia syndrome, or FCS.

2 May 2014

Tel Aviv University pinpoints mechanism that causes rare and severe congenital syndrome

In the 1950s and 1960s, pregnant women with morning sickness were often prescribed the new drug thalidomide. Shortly after the medicine was released on the market, a reported 10,000 infants were born with an extreme form of the rare congenital phocomelia syndrome, which caused death in 50 percent of cases and severe physical and mental disabilities in others.

2 May 2014

Researchers find two types of neurons that enable spinal cord to control skilled forelimb movement

Researchers have identified two types of neurons that enable the spinal cord to control skilled forelimb movement. The first is a group of excitatory interneurons that are needed to make accurate and precise movements; the second is a group of inhibitory interneurons necessary for achieving smooth movement of the limbs.

2 May 2014

Scientists develop experimental drug that prolongs lifespan in mouse model of accelerated aging

Northwestern Medicine- scientists have newly identified a protein's key role in cell and physiological aging and have developed - in collaboration with Tohoku University in Japan -- an experimental drug that inhibits the protein's effect and prolonged the lifespan in a mouse model of accelerated aging.

2 May 2014

Possible link between aggressive prostate cancer and vitamin D deficiency

Vitamin D deficiency was an indicator of aggressive prostate cancer and spread of the disease in European-American and African-American men who underwent their first prostate biopsy because of abnormal prostate-specific antigen (PSA) and/or digital rectal examination (DRE) test results, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

1 May 2014

Genetic biomarkers of ranibizumab response remain elusive in Koreans with AMD

Researchers have failed to find a significant genotypic effect on ranibizumab treatment response in Korean patients with neovascular age-related macular degeneration.

1 May 2014

Genetic susceptibility, dietary antioxidants combine to reduce AMD risk

Dietary intake of antioxidants is associated with a reduced risk of developing early age-related macular degeneration in people at high genetic risk of the condition, pooled analysis of two studies suggests.

1 May 2014

Cutting-edge EmbryoScope technology now available to couples seeking fertility treatment in Florida

The latest in cutting-edge technology, The EmbryoScope, is now available to couples seeking fertility treatment in Florida at IVF FLORIDA Reproductive Associates.

30 Apr 2014

Researchers create tiny, biodegradable nanoparticles that carry DNA to brain cancer cells

Working together, Johns Hopkins biomedical engineers and neurosurgeons report that they have created tiny, biodegradable “nanoparticles” able to carry DNA to brain cancer cells in mice.

30 Apr 2014

Decker Foundation gift helps Binghamton University to establish lab for improving health outcomes

A gift from the Dr. G. Clifford & Florence B. Decker Foundation will enable Binghamton University biologists and their colleagues to conduct tests and research that will improve health outcomes for patients in Southern Tier hospitals with conditions ranging from ear infections to cancer.

30 Apr 2014

Researchers develop tool to identify biogeography of worldwide individuals

Biogeographical data is useful in screening for disease risk and drug sensitivity associated with certain ethnic groups. A team of researchers, including an investigator from Children's Hospital Los Angeles, has developed a tool to accurately identify the biogeography of worldwide individuals. Previous tools were accurate in identifying place of origin within homogeneous European populations but highly inaccurate for places with significant immigration, such as the U.S.

30 Apr 2014

Researchers capture circulating pancreas cells in bloodstream during early stages of pancreatic cancer

Cancer cells are on the move in the bloodstream in the very early stage of pancreatic cancer, and can be detected before cancer is diagnosed, according to research by the University of Michigan Health System.

30 Apr 2014

Researchers develop new strategy to personalised medicine in advanced cancer patients

Tumour cells can accumulate hundreds or even thousands of DNA mutations which induce the growth and spread of cancer. The number and pattern of mutations differs according to the type of tumour, even among those that are classified as part of the same type of tumours.

30 Apr 2014

Higher calcium intake appears to mitigate impact of some of the risk genes for type 2 diabetes

Study shows calcium intake mitigates genetic risk for increased body fat in African-American children, a population with historically low calcium intake and high risk for diabetes.

29 Apr 2014

Armetheon reaches agreement with FDA on SPA for final pivotal trial of tecarfarin

Armetheon, Inc., today announced that it has reached agreement with the U.S. Food and Drug Administration (FDA) on a Special Protocol Assessment (SPA) for the final pivotal trial of tecarfarin.

29 Apr 2014

Genetic News and Research

Research: Novel therapeutic approach to overcome chemoresistance in ovarian cancer

Researchers discover potential genetic variant that may make brains more resilient against Alzheimer's

DNA 'sat nav' allows direct access to homes of ancestors alive 1,000 years ago

Johns Hopkins biochemists figure out HIV-fighting activity of enzyme

New hope for improved diagnosis of children with TB

Isis Pharmaceuticals reports final data from ISIS-APOCIIIRx Phase 2 study in patients with FCS

Tel Aviv University pinpoints mechanism that causes rare and severe congenital syndrome

Researchers find two types of neurons that enable spinal cord to control skilled forelimb movement

Scientists develop experimental drug that prolongs lifespan in mouse model of accelerated aging

Possible link between aggressive prostate cancer and vitamin D deficiency

Genetic biomarkers of ranibizumab response remain elusive in Koreans with AMD

Genetic susceptibility, dietary antioxidants combine to reduce AMD risk

Cutting-edge EmbryoScope technology now available to couples seeking fertility treatment in Florida

Researchers create tiny, biodegradable nanoparticles that carry DNA to brain cancer cells

Decker Foundation gift helps Binghamton University to establish lab for improving health outcomes

Researchers develop tool to identify biogeography of worldwide individuals

Researchers capture circulating pancreas cells in bloodstream during early stages of pancreatic cancer

Researchers develop new strategy to personalised medicine in advanced cancer patients

Higher calcium intake appears to mitigate impact of some of the risk genes for type 2 diabetes

Armetheon reaches agreement with FDA on SPA for final pivotal trial of tecarfarin

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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