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HIV cure research may shift from single-therapy development model to combination therapy trials

The next five years of HIV research should shift gears from the classic single-therapy development model to moving directly from in vitro studies to combination therapy trials, authors argue in a new paper published online today.

25 Sep 2015

Camber Pharmaceuticals releases generic version of Nexium (Esomeprazole) capsules

Camber Pharmaceuticals is pleased to announce that it has launched Esomeprazole Magnesium Delayed-Release Capsules, 20 mg and 40 mg, which is the generic version of Nexium (Esomeprazole) capsules from AstraZeneca Pharmaceuticals. The product is indicated for the treatment of heartburn, gastroesophageal reflux disease (GERD), stomach ulcers, and for a damaged esophagus.

24 Sep 2015

Experts raise questions about FDA’s use of expedited development, approval pathways for new drugs

Two studies carried out by US researchers and published by The BMJ today raise questions about whether most new drugs are any more effective than existing products or whether they have been adequately assessed before approval.

24 Sep 2015

Premature infants in intensive care units exposed to a great deal of pain

Premature infants receiving intensive care are exposed to a great deal of pain, and this pain causes damage to the child. Despite this half of the infants admitted to neonatal intensive units will not receive any pain relief, according to a new European study published today in The Lancet Respiratory Medicine.

24 Sep 2015

Feeling dizzy after standing up may signal serious conditions, increased risk of death

People who get dizzy several minutes after standing up may be at risk of more serious conditions and even an increased risk of death, according to new research published in the September 23, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

24 Sep 2015

City of Hope receives gift to open new Judy and Bernard Briskin Center for Multiple Myeloma Research

The Judy and Bernard Briskin Family Foundation has announced a gift to launch the new Judy and Bernard Briskin Center for Multiple Myeloma Research at City of Hope, the third named center within City of Hope's new Hematologic Malignancies and Stem Cell Transplantation Institute. The generous gift will enable the institution to further its already considerable accomplishments in the field of myeloma treatment and research.

24 Sep 2015

Discovery opens door to more targeted, effective treatments for cancer

In a discovery that could lead to more targeted and effective treatments for certain lung and prostate cancers, researchers at the University of Virginia School of Medicine have identified two new cancer-causing gene mutations - mutations that may be particularly susceptible to cancer-fighting drugs already approved by the federal Food and Drug Administration. One of the gene mutations also may play a key role in early menopause.

24 Sep 2015

Neuroscientists reveal the brain malady responsible for tinnitus, chronic pain

Neuroscientists at Georgetown University Medical Center and Germany's Technische Universität München say they've uncovered the brain malady responsible for tinnitus and for chronic pain — the uncomfortable, sometimes agonizing sensations that persist long after an initial injury.

24 Sep 2015

Research suggests potential drug targets to stop cancer spread

It only takes seconds: one cancerous cell breaks off from a tumor, slips into the bloodstream and quickly lodges elsewhere in the body. These colonizers may bloom into deadly metastatic cancer right away or lie dormant for years, only to trigger a recurrence decades after the primary tumor is removed.

24 Sep 2015

Stanford researchers successfully defeat C. difficile bacteria

Stanford University School of Medicine scientists successfully defeated a dangerous intestinal pathogen, Clostridium difficile, with a drug targeting its toxins rather than its life.

24 Sep 2015

WPI awarded NIH grant to design new pharmaceuticals, simplify manufacturing of existing drugs

The National Institutes of Health has awarded $346,000 to Worcester Polytechnic Institute for a three-year research project to advance development of a chemical process that could significantly improve the ability to design new pharmaceuticals and streamline the manufacturing of existing drugs.

24 Sep 2015

Novel approach promises easier way to detect protein fibers implicated in neuro-degenerative diseases

Liquid crystals are familiar to most of us as the somewhat humdrum stuff used to make computer displays and TVs. Even for scientists, it has not been easy to find other ways of using them.

24 Sep 2015

Scientists trace out intricate molecular pathway that may explain tamoxifen resistance in breast cancer patients

For reasons unknown, many patients with breast cancer treated with the estrogen receptor-blocking drug tamoxifen eventually become resistant to the treatment despite the fact that their cancer cells still have the estrogen receptor proteins that the drug normally targets.

24 Sep 2015

Study raises questions about direct applicability of clinical trial data for cancer drugs

When prescribing newly approved drugs, physicians rely on data from clinical trials to understand the benefits and risks of those drugs for patients. But a study published in the Journal of Oncology Practice showed that for certain cancer drugs, participants in clinical trials are often not representative of the patients that ultimately take the drugs, raising questions about the direct applicability of trial data.

24 Sep 2015

Study explores effectiveness of frontline treatments for couples with unexplained infertility

A breast cancer drug with promise for improving the chance that couples with unexplained infertility can have a baby without increasing their risk of multiple births apparently does not deliver, according to a comparative study.

24 Sep 2015

NGN3-expressing cells in adult human pancreas offer hope to diabetics

Cells that express neurogenin 3 (NGN3) may one day be harnessed to create a plentiful supply of insulin-producing beta cells for the treatment of diabetes, a study led by researchers at the University of South Florida suggests.

24 Sep 2015

ASU and three partner institutions awarded NSF grant to study how healthy brains create memories of odors

Like most animals, we rely on our sense of smell for survival. It's critical to our health and an important factor in our quality of life.

23 Sep 2015

Researchers extend innovative research towards a cure for type I diabetes

Associate Professor Shane Grey, of Sydney's Garvan Institute of Medical Research, together with collaborators from the Westmead Millennium Institute for Medical Research and the Children's Hospital at Westmead, have been awarded $3.3 million to extend their innovative research towards a cure for type I diabetes.

23 Sep 2015

Johns Hopkins trained physicians create start-up to produce cheap generic drugs

A group of Johns Hopkins trained physicians has started a crowdfunding campaign to create a start-up which produces cheap generic drugs.

23 Sep 2015

Researchers receive NIH grants to find genomic regions containing variants that affect disease risk

Six new grants from the National Institutes of Health will support researchers to develop new computational approaches for searching among millions of genomic variants to find those that make a difference in disease susceptibility or in other traits.

23 Sep 2015

Drugs News and Research

HIV cure research may shift from single-therapy development model to combination therapy trials

Camber Pharmaceuticals releases generic version of Nexium (Esomeprazole) capsules

Experts raise questions about FDA’s use of expedited development, approval pathways for new drugs

Premature infants in intensive care units exposed to a great deal of pain

Feeling dizzy after standing up may signal serious conditions, increased risk of death

City of Hope receives gift to open new Judy and Bernard Briskin Center for Multiple Myeloma Research

Discovery opens door to more targeted, effective treatments for cancer

Neuroscientists reveal the brain malady responsible for tinnitus, chronic pain

Research suggests potential drug targets to stop cancer spread

Stanford researchers successfully defeat C. difficile bacteria

WPI awarded NIH grant to design new pharmaceuticals, simplify manufacturing of existing drugs

Novel approach promises easier way to detect protein fibers implicated in neuro-degenerative diseases

Scientists trace out intricate molecular pathway that may explain tamoxifen resistance in breast cancer patients

Study raises questions about direct applicability of clinical trial data for cancer drugs

Study explores effectiveness of frontline treatments for couples with unexplained infertility

NGN3-expressing cells in adult human pancreas offer hope to diabetics

ASU and three partner institutions awarded NSF grant to study how healthy brains create memories of odors

Researchers extend innovative research towards a cure for type I diabetes

Johns Hopkins trained physicians create start-up to produce cheap generic drugs

Researchers receive NIH grants to find genomic regions containing variants that affect disease risk

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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