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Researchers use new software tool to identify genetic overlaps between palmitoleic acid and Crohn's disease

Some research has suggested that omega-3 fatty acids, abundant in fish oils, can relieve inflammation in Crohn's disease. But a new study using software developed by Duke scientists hints that we should be paying closer attention to what the other omegas -- namely, omega-6 and omega-7 -- are doing to improve or worsen the disease.

16 Sep 2015

UCSF receives $5 million grant to create online database on all types of cancer

UC San Francisco has received a National Cancer Institute grant of $5 million over the next five years to lead a massive effort to integrate the data from all experimental models across all types of cancer.

16 Sep 2015

Common hypertension drugs worsen cardiovascular outcomes in hypertensive African Americans

Drugs commonly used to treat high blood pressure, and prevent heart attacks and strokes, are associated with significantly worse cardiovascular outcomes in hypertensive African Americans compared to whites, according to a new comparative effectiveness research study led by researchers in the Department of Population Health at NYU Langone Medical Center.

15 Sep 2015

Change Healthcare partners with RxREVU to provide customers with prescription decision support

Change Healthcare, a market leader in healthcare consumer engagement and cost and quality transparency, has joined forces with RxREVU to deliver an enhanced medication selection experience to help consumers, payers and providers make more informed decisions about treatment options, especially those pertaining to therapeutic alternatives.

15 Sep 2015

Roflumilast drug could inhibit growth of brain tumor in children

Current drugs may stop working against the most common type of brain tumor in children, medulloblastoma, but the tumor could be targeted in a new way, according to Stanford University scientists.

15 Sep 2015

Experts and researchers develop new classification criteria for gout

A panel of experts and researchers have developed a new classification system for gout, the most common form of inflammatory arthritis. This new system standardizes the classification of this condition using a variety of evidence-based criteria.

15 Sep 2015

Cerilliant offers first-ever multi-component solutions for qualitative evaluation of drug interference

Sigma-Aldrich Corporation today announced that the Cerilliant® brand within its Applied Diagnostics and Testing business segment now offers the first-ever reference solutions for qualitative evaluation of drug interferences in a testing laboratory's analytical methods.

15 Sep 2015

Population health study examines real-world osteoporosis treatment patterns

A statewide study has found that from 2005 to 2012, fewer than a quarter of men and women with documentation of osteoporosis or fragility fracture, conditions for which national guidelines would recommend treatment for osteoporosis, actually received that treatment.

15 Sep 2015

Findings suggest link between cancer drug resistance and reactive oxygen species found in mitochondria

Increased levels of certain chemically reactive, oxygen-containing molecules in the body can cause patients to become resistant to cancer drugs such as chemotherapy, according to researchers at Georgia State University.

15 Sep 2015

Cautiously-designed combination therapies may attenuate side effects associated with Alzheimer's drugs

BACE1 is the major drug target for Alzheimer's disease, but we know surprisingly little about its normal function in the CNS.

15 Sep 2015

UCI researchers uncover new underlying factor of seizures

University of California, Irvine researchers with the School of Medicine have identified the mechanism by which valproic acid controls epileptic seizures, and by doing so, also revealed an underlying factor of seizures.

15 Sep 2015

UT Southwestern evaluates allopurinol drug to prevent nephropathy in Type I diabetes patients

UT Southwestern Medical Center has joined an international clinical trial studying whether a drug traditionally used to treat gout can help prevent kidney damage in patients with Type 1 diabetes.

15 Sep 2015

Ex-vivo lung perfusion technique can reduce risk of transplant rejection

University of Manchester researchers have used a new technique to recondition poorly functioning lungs and remove donor white blood cells in an attempt to increase the number of lungs available for transplant, and at the same time reduce the risk of acute rejection.

15 Sep 2015

$Whole-genome sequencing identifies EN1 gene as determinant of bone mineral density, fracture$

Whole-genome sequencing identifies EN1 gene as determinant of bone mineral density, fracture

Using extensive genetic data compiled by the UK10K project, an international team of researchers led by Dr. Brent Richards of the Lady Davis Institute at the Jewish General Hospital has identified a genetic variant near the gene EN1 as having the strongest effect on bone mineral density (BMD) and fracture identified to date.

15 Sep 2015

Molecular biology research holds promise in understanding cancer growth, aging

Researchers at the Johns Hopkins University have found molecular evidence of how a biochemical process controls the lengths of protective chromosome tips, a potentially significant step in ultimately understanding cancer growth and aging.

15 Sep 2015

BfArM approves Greenovation’s moss-aGal phase I clinical trial for Fabry disease

Greenovation Biotech GmbH announced today that it has received approval to begin a phase I clinical trial in Europe for its first drug candidate moss-aGal (agalsidase) from Germany's regulatory authority, the Federal Institute for Drugs and Medical Devices (BfArM).

15 Sep 2015

Sun Biomedical begins DMX-200 Phase II trial for treatment of chronic kidney disease

Sun Biomedical Limited today announced the first patient had been enrolled in a Phase II study of DMX-200, an innovative new treatment that combines two different drugs to treat chronic kidney disease.

15 Sep 2015

Combining epigenetic drugs with immunotherapies may provide additional clinical benefit to cancer patients

Recent data suggest that epigenetic therapies are likely to provide additional clinical benefit to cancer patients when rationally combined with immunotherapeutic drugs, according to a review published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

15 Sep 2015

FDA grants Orphan Drug Designation to TxCell's Col-Treg for treatment of autoimmune uveitis

TxCell SA, a biotechnology company developing innovative, personalized T cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today that the U.S. Food and Drug Administration's Office of Orphan Products Development has granted Orphan Drug Designation (ODD) to TxCell's Col-Treg, a personalized T cell immunotherapy using collagen-II specific regulatory T-cells, for the treatment of chronic non-infectious uveitis.

15 Sep 2015

Three-drug strategy effective against drug-resistant staph infection, finds new research

Three antibiotics that, individually, are not effective against a drug-resistant staph infection can kill the deadly pathogen when combined as a trio, according to new research.

15 Sep 2015

Drugs News and Research

Researchers use new software tool to identify genetic overlaps between palmitoleic acid and Crohn's disease

UCSF receives $5 million grant to create online database on all types of cancer

Common hypertension drugs worsen cardiovascular outcomes in hypertensive African Americans

Change Healthcare partners with RxREVU to provide customers with prescription decision support

Roflumilast drug could inhibit growth of brain tumor in children

Experts and researchers develop new classification criteria for gout

Cerilliant offers first-ever multi-component solutions for qualitative evaluation of drug interference

Population health study examines real-world osteoporosis treatment patterns

Findings suggest link between cancer drug resistance and reactive oxygen species found in mitochondria

Cautiously-designed combination therapies may attenuate side effects associated with Alzheimer's drugs

UCI researchers uncover new underlying factor of seizures

UT Southwestern evaluates allopurinol drug to prevent nephropathy in Type I diabetes patients

Ex-vivo lung perfusion technique can reduce risk of transplant rejection

Whole-genome sequencing identifies EN1 gene as determinant of bone mineral density, fracture

Molecular biology research holds promise in understanding cancer growth, aging

BfArM approves Greenovation’s moss-aGal phase I clinical trial for Fabry disease

Sun Biomedical begins DMX-200 Phase II trial for treatment of chronic kidney disease

Combining epigenetic drugs with immunotherapies may provide additional clinical benefit to cancer patients

FDA grants Orphan Drug Designation to TxCell's Col-Treg for treatment of autoimmune uveitis

Three-drug strategy effective against drug-resistant staph infection, finds new research

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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