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Antidepressants can increase depression, mood cycling in rapid-cycling bipolar disorder patients

In patients with rapid-cycling bipolar disorder, antidepressants can increase incidents of depression and mood cycling. Rif S. El-Mallakh, M.D., director of the Mood Disorders Clinical and Research Program at the University of Louisville, along with Nassir Ghaemi, M.D., of Tufts University and other researchers, conducted the first randomized clinical trial that analyzes how modern antidepressants affect patients with rapid-cycling (RC) bipolar disorder (BD).

15 Sep 2015

Communicating risk status to at-risk Alzheimer's patients

How would you feel, as a cognitively healthy person, if a doctor said you had high odds of developing Alzheimer's disease within two to five years?

14 Sep 2015

UN reports that more needs to be done so all children are born HIV and syphilis free in Asia-Pacific region

The Asia–Pacific region has made significant progress in efforts to eliminate HIV and syphilis, but thousands of mothers and children have yet to feel the benefits.

14 Sep 2015

Better treatment could be on the horizon for Myasthenia Gravis

Myasthenia Gravis (MG) is a debilitating and potentially deadly disease that can afflict anyone, characterized by severe muscle weakness, affecting control of facial expressions, arm and leg movements, chewing, swallowing, coughing and breathing. There is no cure, only treatment.

14 Sep 2015

US-Ireland partnership awarded £2.9m to develop nanomedicine for treatment of pancreatic cancer

A US-Ireland partnership involving researchers at Queen's University Belfast has been awarded £2.9m to develop new treatments for pancreatic cancer, which is the fifth most common cause of cancer deaths in the UK.

14 Sep 2015

NYUCN researchers study sexual transmission of HCV among HIV-positive MSM

While sexual contact is not the most efficient means of hepatitis C (HCV) transmission, there have been several reports of outbreaks of sexually transmitted HCV in HIV-positive men who have sex with men (MSM). HCV infections are more likely to become persistent and to lead to progressive liver disease in people who are HIV-infected, even if they are receiving HIV treatment. Factors underlying these infections in HIV-positive MSM are only partially understood.

14 Sep 2015

Genetics and race influence patients' response to anticancer drug treatments

A new study published in Pharmacogenomics suggests that a person's response to anticancer drug treatments is strongly related to their genetic ancestry. Pharmacogenomics is published by Future Science Group.

14 Sep 2015

New treatment protocol can improve outcomes for babies with neonatal abstinence syndrome

A new protocol to treat babies born in withdrawal from drugs can be used widely to improve outcomes for these babies. The protocol reduces length of stay and the duration of treatment with opioids that are used therapeutically to wean babies off of drugs.

14 Sep 2015

Diabetes drug 'suffocates' pancreatic cancer stem cells, new study finds

A new study shows that pancreatic cancer stem cells (PancSCs) are virtually addicted to oxygen-based metabolism, and could be "suffocated" with a drug already used to treat diabetes.

14 Sep 2015

Two St. Louis institutions collaborate to create Center for Clinical Pharmacology

St. Louis College of Pharmacy and Washington University School of Medicine in St. Louis are joining forces to find better, safer and more effective ways to use prescription medications to improve health. Researchers from the two institutions are collaborating to create the Center for Clinical Pharmacology.

14 Sep 2015

New technique could improve selectivity of cancer drugs, decrease unwanted side effects in future

A class of therapeutic drugs known as protein kinase inhibitors has in the past decade become a powerful weapon in the fight against various life-threatening diseases, including certain types of leukemia, lung cancer, kidney cancer and squamous cell cancer of the head and neck.

11 Sep 2015

Aridis' AR-301 granted FDA Fast Track Designation for treatment of pneumonia caused by S. aureus

Aridis Pharmaceuticals, Inc., a biopharmaceutical company applying proprietary technologies to produce novel anti-infectives and immunotherapies for infectious diseases, announced today that the U.S. Food and Drug Administration granted Fast Track Designation to AR-301, the Company's fully human anti-Staphylococcal alpha-toxin IgG1 monoclonal antibody (mAb).

11 Sep 2015

Researchers find key cellular enzyme that could be effective drug target for urologic cancer cells

Researchers at the SUNY Upstate Medical University have found that a key cellular enzyme, c-Abl, could be an effective drug target in cancer cells for urologic cancers, such as prostate and kidney.

11 Sep 2015

Study shows half of adolescents misuse their prescription drugs

Although prescription drug misuse is on the decline among adolescents, one in two patients tested between the ages of 10 and 17 years are not using their medications appropriately, potentially putting their health at risk, according to an analysis by Quest Diagnostics (NYSE: DGX), the world's leading provider of diagnostic information services.

From Quest Diagnostics 11 Sep 2015

Researchers now have a way to study special proteins linked to different diseases, cancer

Researchers from Northwestern University and Yale University have developed a user-friendly technology to help scientists understand how proteins work and fix them when they are broken. Such knowledge could pave the way for new drugs for a myriad of diseases, including cancer.

11 Sep 2015

NYU's Jin Kim Montclare develops dual-delivery system to potentially treat multi-drug resistant cancer cells

The National Science Foundation recently funded research aimed at developing an engineered protein-lipid system that simultaneously delivers genes and drugs for the potential treatment of multi-drug resistant cancer cells. The dual-delivery system could also apply to diabetes and other conditions requiring a variety of therapeutic approaches.

11 Sep 2015

BioDelivery Sciences and Endo present Phase 2 data on buprenorphine HCl buccal film in patients with chronic pain

Endo Pharmaceuticals Inc., a subsidiary of Endo International plc, and BioDelivery Sciences International, Inc. today presented data from a Phase 2 study for the investigational drug buprenorphine HCl buccal film utilizing BDSI’s patented BioErodible MucoAdhesive (BEMA) drug delivery technology.

11 Sep 2015

Scientists elucidate genetic interaction that may prove key to development, progression of glaucoma

Scientists at the University of California, San Diego School of Medicine have elucidated a genetic interaction that may prove key to the development and progression of glaucoma, a blinding neurodegenerative disease that affects tens of millions of people worldwide and is a leading cause of irreversible blindness.

11 Sep 2015

Innovative technologies offer hope to people living with chronic pain

More than 100 million people in this country have pain that won't go away. Many of these chronic pain sufferers fail to get relief from pills, shots and even surgery, while others temporarily trade the pain for side effects such as drowsiness or digestive problems.

11 Sep 2015

Nurse-trainer uses new approach to teach correct combination of HIV drugs to Angola's nurses

Nurse-trainer Helena Cumbelembe Inacio was struggling to teach nurses at the health center here the correct combination of medicines to prevent pregnant women with HIV from passing the infection to their children.

11 Sep 2015

Drugs News and Research

Antidepressants can increase depression, mood cycling in rapid-cycling bipolar disorder patients

Communicating risk status to at-risk Alzheimer's patients

UN reports that more needs to be done so all children are born HIV and syphilis free in Asia-Pacific region

Better treatment could be on the horizon for Myasthenia Gravis

US-Ireland partnership awarded £2.9m to develop nanomedicine for treatment of pancreatic cancer

NYUCN researchers study sexual transmission of HCV among HIV-positive MSM

Genetics and race influence patients' response to anticancer drug treatments

New treatment protocol can improve outcomes for babies with neonatal abstinence syndrome

Diabetes drug 'suffocates' pancreatic cancer stem cells, new study finds

Two St. Louis institutions collaborate to create Center for Clinical Pharmacology

New technique could improve selectivity of cancer drugs, decrease unwanted side effects in future

Aridis' AR-301 granted FDA Fast Track Designation for treatment of pneumonia caused by S. aureus

Researchers find key cellular enzyme that could be effective drug target for urologic cancer cells

Study shows half of adolescents misuse their prescription drugs

Researchers now have a way to study special proteins linked to different diseases, cancer

NYU's Jin Kim Montclare develops dual-delivery system to potentially treat multi-drug resistant cancer cells

BioDelivery Sciences and Endo present Phase 2 data on buprenorphine HCl buccal film in patients with chronic pain

Scientists elucidate genetic interaction that may prove key to development, progression of glaucoma

Innovative technologies offer hope to people living with chronic pain

Nurse-trainer uses new approach to teach correct combination of HIV drugs to Angola's nurses

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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