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Analysis of landmark vitamin C study challenges the WHO's recommended daily amounts

It was wartime and food was scarce. Leaders of England's effort to wage war and help the public survive during World War II needed to know: Were the rations in lifeboats adequate for survival at sea? And, among several experiments important for public as well as military heath, how much vitamin C did a person need to avoid the deadly disease scurvy?

16 Aug 2021

Hedgehog-signaling inhibitor may shift tumor-associated macrophages back to cancer fighters

A form of cell communication called hedgehog signaling is vital for embryonic development in mammals.

16 Aug 2021

Nitrogen-doped fluorescent carbon dots for detecting iodide ion, curcumin in biological and food samples

The ability to reliably and accurately detect levels of iodide ion and curcumin is crucial in the fields of food and life sciences.

16 Aug 2021

Viral load could not predict transmissibility of SARS-CoV-2, study finds

The transmission of SARS-CoV-2 virus is dependent on many factors. Although some in vitro studies indicate that the amount of virus isolated from infected individuals affects the successful rate of virus transmission, whether the viral load carried at the individual level can determine transmissibility was unknown.

16 Aug 2021

Brain’s structural and functional alignment can vary with sex, age and may be genetic, study suggests

The degree to which the brain's wiring aligns with its patterns of activity can vary with sex and age, and may be genetic, suggests a study published by Weill Cornell Medicine investigators. The study finds that this alignment may also have implications on cognition.

16 Aug 2021

Experimental drug and immunotherapy combination shows promise in bladder cancer study

A new study in mice found that adding the experimental drug entinostat to an immunotherapy-like treatment substantially boosted cancer remission.

16 Aug 2021

Treatment with stem cell grafts promotes tendon healing in sheep

Tendon injuries in sheep that were treated with stem cell grafts achieved, in just two months, a diameter and hardness similar to the original healthy tendon, according to the results of a study released in STEM CELLS Translational Medicine.

16 Aug 2021

Small protein prevents immune system from destroying pancreatic cells in type 1 diabetes-prone mice

A new study has shown that treating type 1 diabetes-prone mice with the small protein MOTS-c prevented the immune system from destroying insulin-producing pancreatic cells, effectively preventing the onset of the autoimmune disease.

16 Aug 2021

Bioengineers develop implantable piezoelectric therapeutic devices

Bioengineers have developed biocompatible generators that create electrical pulses when compressed by body motions.

16 Aug 2021

Combining inhibitor drug with immunotherapy agent improves response in cancer patients

Combining a histone deacetylase inhibitor drug with immunotherapy agents is safe, and may benefit some patients with advanced cancers that have not responded to traditional therapy, according to results of a phase 1 clinical trial led by researchers at the Johns Hopkins Kimmel Cancer Center, Bloomberg~Kimmel Institute for Cancer Immunotherapy and several other centers including University of Pittsburgh Cancer Institute, Yale Cancer Center and City of Hope in Los Angeles, which participated in study enrollment, and the University of Southern California and University College Cork in Ireland, which collaborated on analysis of the data.

16 Aug 2021

Having a good listener is associated with greater cognitive resilience

Supportive social interactions in adulthood are important for your ability to stave off cognitive decline despite brain aging or neuropathological changes such as those present in Alzheimer's disease, a new study finds.

16 Aug 2021

Single two-hour session of pain management skills could offer as much benefit as longer-course of CBT

A single two-hour session of a pain management skills class could offer as much benefit as eight sessions of cognitive behavioral therapy (CBT) for patients experiencing chronic low-back pain (CLBP), suggests a study published in JAMA Network Open.

16 Aug 2021

Study identifies mechanism of resistance and presents a much-needed target for advanced leukemias

Too many "exhausted" T cells left in the wake of aggressive chemotherapy regimens for patients with advanced chronic lymphocytic leukemia (CLL) make it more challenging for chimeric antigen receptor (CAR) T cell therapy to do its job.

16 Aug 2021

NIH scientists develop new sample preparation method to detect SARS-CoV-2

Scientists at the National Institutes of Health (NIH) have developed a new sample preparation method to detect SARS-Cov-2, the virus that causes COVID-19.

16 Aug 2021

Penn researchers reveal complex details of T-cell responses to mRNA COVID-19 vaccines

Messenger-RNA (mRNA) vaccines against the coronavirus that causes COVID-19 provoke a swift and strong response by the immune system's T cells - the heavy armor of the immune system - according to a study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

16 Aug 2021

Research reveals increased risk of heart problems associated with night shift work

People who work night shifts are at increased risk of developing an irregular and often abnormally fast heart rhythm called atrial fibrillation (AF), according to research published in the European Heart Journal.

16 Aug 2021

Blood clotting markers found to be elevated in patients with Long COVID syndrome

New evidence shows that patients with Long COVID syndrome continue to have higher measures of blood clotting, which may help explain their persistent symptoms, such as reduced physical fitness and fatigue.

16 Aug 2021

In rural America, twisting arms to take a covid vaccine first takes trust

Lee Wright was hard at work, constructing a nail salon near the city's abandoned hospital, when Jody Johnson stopped by to introduce himself on a recent afternoon.

16 Aug 2021

Children in poverty have smaller volumes of certain subcortical brain regions, study finds

Children in poverty are more likely to have cognitive and behavioral difficulties than their better-off peers. Plenty of past research has looked into the physical effects of childhood poverty, or documented mental health disparities between socioeconomic classes.

16 Aug 2021

Study explores how racial minorities have been unequally affected by the COVID-19 pandemic

Racial minorities comprise around a quarter of Utah's population but represent a third of COVID-19 cases in the state. A similar story has played out across the country. Why have racial minorities been unequally affected by the COVID-19 pandemic?

16 Aug 2021

Medicine News and Research

Analysis of landmark vitamin C study challenges the WHO's recommended daily amounts

Hedgehog-signaling inhibitor may shift tumor-associated macrophages back to cancer fighters

Nitrogen-doped fluorescent carbon dots for detecting iodide ion, curcumin in biological and food samples

Viral load could not predict transmissibility of SARS-CoV-2, study finds

Brain’s structural and functional alignment can vary with sex, age and may be genetic, study suggests

Experimental drug and immunotherapy combination shows promise in bladder cancer study

Treatment with stem cell grafts promotes tendon healing in sheep

Small protein prevents immune system from destroying pancreatic cells in type 1 diabetes-prone mice

Bioengineers develop implantable piezoelectric therapeutic devices

Combining inhibitor drug with immunotherapy agent improves response in cancer patients

Having a good listener is associated with greater cognitive resilience

Single two-hour session of pain management skills could offer as much benefit as longer-course of CBT

Study identifies mechanism of resistance and presents a much-needed target for advanced leukemias

NIH scientists develop new sample preparation method to detect SARS-CoV-2

Penn researchers reveal complex details of T-cell responses to mRNA COVID-19 vaccines

Research reveals increased risk of heart problems associated with night shift work

Blood clotting markers found to be elevated in patients with Long COVID syndrome

In rural America, twisting arms to take a covid vaccine first takes trust

Children in poverty have smaller volumes of certain subcortical brain regions, study finds

Study explores how racial minorities have been unequally affected by the COVID-19 pandemic

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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