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Study identifies genetic variants linked to Hirschsprung’s disease

Genetic studies in humans, zebrafish and mice have revealed how two different types of genetic variations team up to cause a rare condition called Hirschsprung’s disease. The findings add to an increasingly clear picture of how flaws in early nerve development lead to poor colon function, which must often be surgically corrected.

8 Apr 2015

MabVax closes $11.6 million in private placement

MabVax Therapeutics Holdings, Inc., a clinical-stage cancer immunotherapy company, is pleased to announce that it has closed on gross proceeds of approximately $11.6 million in a private placement (the "Private Placement") led by OPKO Health, Inc. and Dr. Phillip Frost, CEO and Chairman of OPKO Health.

6 Apr 2015

UC Davis researchers unravel how micro RNA could potentially lead to novel cancer therapies

The micro RNA miR-22 has long been known for its ability to suppress cancer. However, questions remain about how it achieves this feat. For example, which molecules are regulating miR-22, and which are miR22 targets?

6 Apr 2015

Leukemia drug could prevent and control growth of colorectal tumours

Scientists from Nanyang Technological University (NTU Singapore) and Sweden's Karolinska Institutet, one of Europe's largest and most prestigious medical universities, have discovered that an existing chemotherapy drug used to treat leukaemia could prevent and control the growth of colorectal tumours.

3 Apr 2015

American Cancer Society awards 100 national research and training grants for cancer studies

The American Cancer Society, the largest non-government, not-for-profit funding source of cancer research in the United States, has awarded 100 national research and training grants totaling more than $45.6 million in the first of two grant cycles for 2015.

2 Apr 2015

Minimally invasive laparoscopic surgery significantly lowers health care costs

Adding to the clinical benefits and improved patient outcomes associated with minimally invasive surgery, Medtronic highlighted a study published in the March 25 online edition of JAMA Surgery. The new study demonstrated that patients who underwent laparoscopic colectomy procedures required fewer days of health care utilization and the health care system spent less on their acute and follow-up care than those who underwent traditional open surgery.

31 Mar 2015

New study finds that walnuts have potential to benefit overall health

Multiple new research abstracts suggest walnuts may have the potential to positively affect several important health factors. From their impact on colon cancer and certain aspects of cognitive aging, to their positive effect on both gut health and vascular health, the research findings presented at Experimental Biology 2015 detail our latest understanding of walnuts' inner workings.

31 Mar 2015

Drug-resistant E. coli outbreak linked to contaminated endoscopes in Washington state hospital

An outbreak of a novel Escherichia coli (E. coli) strain resistant to antibiotics has been linked to contaminated endoscopes in a Washington state hospital. The study indicates that industry standard cleaning guidelines, which were exceeded by hospital staff, may not be sufficient for sterilizing endoscopes adequately.

31 Mar 2015

New bowel cancer screening test demonstrates major increase in participation rates

A large pilot study of a new bowel cancer screening test has demonstrated a major increase in participation rates across population groups.

31 Mar 2015

Researchers identify bio-markers that could help detect early stage colorectal cancer

Colorectal cancer is the third most common form of cancer globally and the second most common cause of cancer deaths. The chance of a cure is high if the cancer is detected early enough, but early detection is not a given. Researchers from VIB and KU Leuven - together with various European oncology centers, including UZ Leuven - have identified bio-markers that can be incorporated in a new diagnostic test.

30 Mar 2015

Study finds C. difficile infection increases hospital readmission rates

Patients with Clostridium difficile infection (CDI) are twice as likely to be readmitted to the hospital as patients without the deadly diarrheal infection, according to a study published in the April issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology.

30 Mar 2015

Minimally-invasive surgery offers long-term cost savings for healthcare system, less trauma for patients

Adding to the clinical benefits and improved patient outcomes associated with minimally-invasive surgery (MIS), Medtronic plc today highlighted new data demonstrating that patients who underwent minimally invasive colon resection procedures were able to leave the hospital faster, visit their doctors less for follow up care and take fewer medicines than those who underwent open surgery.

27 Mar 2015

DNA samples collected from tampons may help detect endometrial cancer

Researchers at Mayo Clinic have shown that it is possible to detect endometrial cancer using tumor DNA picked up by ordinary tampons. The new approach specifically examines DNA samples from vaginal secretions for the presence of chemical "off" switches — known as methylation — that can disable genes that normally keep cancer in check.

25 Mar 2015

Vitamin D3 and metformin show promising results in preventing colorectal cancer

The concept was simple: If two compounds each individually show promise in preventing colon cancer, surely it's worth trying the two together to see if even greater impact is possible.

24 Mar 2015

How our DNA may prevent bowel cancer

The link between taking aspirin, and similar medications called non-steroidal anti-inflammatory drugs (or NSAIDS), and bowel (colorectal) cancer prevention is well established.

23 Mar 2015

New strategies to improve screening rates for colorectal cancer in low-income populations

Since the colonoscopy was developed more than four decades ago, the screening procedure for colorectal cancer has undoubtedly saved millions of lives.

20 Mar 2015

New pre-clinical, clinical data for IMBRUVICA to be highlighted at AACR Annual Meeting

Pharmacyclics, Inc. today announced that new pre-clinical and clinical data for ibrutinib (IMBRUVICA) will be highlighted at the 2015 American Association for Cancer Research Annual Meeting to be held April 18 – 22, 2015, in Philadelphia, PA.

19 Mar 2015

Genetic markers may help decide who benefits from aspirin, NSAIDs in lowering risk of colorectal cancer

An Indiana University cancer researcher and her colleagues have identified genetic markers that may help determine who benefits from regular use of aspirin and other nonsteroidal anti-inflammatory drugs for lowering one's risk of developing colorectal cancer.

18 Mar 2015

Loyola's Neil Gupta recommends patients to ask four questions when planning a colonoscopy

"Most people focus on the dislike of the preparation, the need to arrange transportation and the fear of being anesthetized during the procedure and then potentially getting a cancer diagnosis," says Neil Gupta, MD, MPH, Director of Endoscopy at Loyola University Health System. "Screening colonoscopy is a very critical examination that really can determine life and death when it comes to colon cancer. It is now clear that not every colonoscopy is equal. Once you've decided it's time to get a screening colonoscopy, the next step is to make sure that you get a high-quality one."

17 Mar 2015

Penn researchers find evidence of new culprit in colon cancer

Colon cancer is a heavily studied disease -- and for good reason. It is one of the leading causes of cancer-related deaths worldwide, and its numbers are on the rise, from 500,00 deaths in 1990 to 700,000 in 2010.

17 Mar 2015

Colon News and Research

Study identifies genetic variants linked to Hirschsprung’s disease

MabVax closes $11.6 million in private placement

UC Davis researchers unravel how micro RNA could potentially lead to novel cancer therapies

Leukemia drug could prevent and control growth of colorectal tumours

American Cancer Society awards 100 national research and training grants for cancer studies

Minimally invasive laparoscopic surgery significantly lowers health care costs

New study finds that walnuts have potential to benefit overall health

Drug-resistant E. coli outbreak linked to contaminated endoscopes in Washington state hospital

New bowel cancer screening test demonstrates major increase in participation rates

Researchers identify bio-markers that could help detect early stage colorectal cancer

Study finds C. difficile infection increases hospital readmission rates

Minimally-invasive surgery offers long-term cost savings for healthcare system, less trauma for patients

DNA samples collected from tampons may help detect endometrial cancer

Vitamin D3 and metformin show promising results in preventing colorectal cancer

How our DNA may prevent bowel cancer

New strategies to improve screening rates for colorectal cancer in low-income populations

New pre-clinical, clinical data for IMBRUVICA to be highlighted at AACR Annual Meeting

Genetic markers may help decide who benefits from aspirin, NSAIDs in lowering risk of colorectal cancer

Loyola's Neil Gupta recommends patients to ask four questions when planning a colonoscopy

Penn researchers find evidence of new culprit in colon cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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