Coronavirus News and Research

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First data on Pfizer-BioNTech's Omicron BA.4/5 combination vaccine

In a recent study posted to the bioRxiv* preprint server, researchers from Germany and the United States analyzed the association between exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.4/BA.5 spike glycoprotein and pan-Omicron neutralization.

27 Sep 2022

Researchers uncover a new way the immune system detects coronavirus infection

In a recent study posted to bioRxiv*, researchers in the United States demonstrated that the main protease (Mpro) of coronaviruses (CoVs) activates host inflammasome responses.

27 Sep 2022

Review says dose of approved COVID-19 vaccines based on weak evidence

A recent study posted to the medRxiv* preprint server reviewed early-phase dose-finding trials to examine the study design, safety, and early antibody response data on approved coronavirus disease 2019 (COVID-19) vaccines and gain insights on design improvements for future candidate COVID-19 vaccine clinical trials.

26 Sep 2022

Study looks at boosting with variant-derived COVID vaccine

In a recent study posted to bioRxiv*, researchers at Washington University School of Medicine, St. Louis, demonstrated that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine booster elicits robust germinal center (GC) B cell responses.

26 Sep 2022

Study characterizes immunological signature of SARS-CoV-2 infection in children

A recent study has demonstrated that the clinical severity of COVID-19 in children depends on the dynamics of immune response induced by SARS-CoV-2 infection.

26 Sep 2022

Study finds remdesivir-resistant version of COVID-19 in renal transplant recipients

Recent studies have shown that patients with weakened immune systems—which enables the virus that causes COVID-19 to remain longer in the body, copy itself, and continually change—may enable the development of new, slightly different versions of the virus (variants).

26 Sep 2022

Researchers explore neurological manifestations among long COVID patients

In a new study, researchers assessed the long-term neurological sequelae in the post-acute phase of coronavirus disease 2019 (COVID-19) or long COVD.

26 Sep 2022

Study demonstrates how pan-sarbecovirus ORF7a protein plays a role in evading host immunity

In a new study, researchers demonstrated how sarbecovirus family down-regulates major histocompatibility complex-I (MHC-I) surface expression to evade cellular immunity.

26 Sep 2022

Systemic inflammation triggered by SARS-CoV-2 found to cause human testicular injury

In a new study, a team of researchers demonstrated that testicular injury in humans is not due to direct SARS-CoV-2 infection but more likely is an indirect effect of exposure to systemic inflammation or SARS-CoV-2 antigens.

26 Sep 2022

Study investigates long-range RNA-RNA interactions of SARS-CoV-2

Researchers explored RRIs [long-range ribonucleic acid (RNA)-RNA interactions] in SARS-CoV-2 variants of concern genomes to assess evolutionary changes in SARS-CoV-2.

26 Sep 2022

Omicron BA.1 breakthrough infection in vaccinated individuals recall memory B cells to confer immunity

In a new study, researchers followed up with individuals vaccinated with a COVID-19 vaccine based on the mRNA platform up to six months following Omicron BA.1 breakthrough infection to trace the evolution of their antibody immunity.

26 Sep 2022

Resistance of Russian Rhinolophus bats containing ACE2-dependent sarbecoviruses to COVID-19 vaccines

In a new study, researchers investigated the receptor tropism and serological cross-reactivity for spike (S) protein receptor-binding domains from two clade 3 sarbecoviruses found in Russian Rhinolophus (horseshoe) bats.

26 Sep 2022

Is covid ‘under control’ in the US? Experts say yes

President Joe Biden caused a stir in a “60 Minutes” interview on Sept. 18 when he declared that the covid-19 pandemic is over.

26 Sep 2022

What is the association between body fat and COVID-19?

Researchers recently assessed the association between adipose tissues and COVID-19 by evaluating autopsy cases and profiling adipose tissue responses to SARS-CoV-2 infections.

26 Sep 2022

Long-term follow-up of young people with COVID-19 vaccine myocarditis

In a recent study, researchers surveyed a comprehensive range of outcomes in patients diagnosed with myocarditis after COVID-19 vaccination in the United States.

26 Sep 2022

How effective are live-attenuated SARS-CoV-2 vaccines?

Researchers opined on the use of live-attenuated whole virus vaccines as COVID-19 vaccines.

26 Sep 2022

Are we consuming microplastics through take-out food?

In a recent Environmental Research study, scientists detected and measured microplastics directly from take-out food.

26 Sep 2022

Common germline variants of APOE contribute to differential COVID-19 outcomes

Researchers investigated the relationship between APOE4 genotype and COVID-19 outcomes using genetic models of mice.

26 Sep 2022

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

Researchers presented the direct plasmid transfection method for SARS-CoV-2 virus-like particle production in insect cells and applied the VLPs to evaluate the efficacy of monoclonal antibodies and vaccinated donor sera.

26 Sep 2022

Study of 9 million Swedes shows rapidly declining effectiveness of COVID vaccines against Omicron

The findings of a new Swedish study posted to the Preprints with The Lancet* server found that two COVID-19 vaccine doses provided effective long-term protection against infection before Omicron, but less protection against Omicron infection (dropping to 43% by week four and no protection by week 14).

25 Sep 2022

Coronavirus News and Research

First data on Pfizer-BioNTech's Omicron BA.4/5 combination vaccine

Researchers uncover a new way the immune system detects coronavirus infection

Review says dose of approved COVID-19 vaccines based on weak evidence

Study looks at boosting with variant-derived COVID vaccine

Study characterizes immunological signature of SARS-CoV-2 infection in children

Study finds remdesivir-resistant version of COVID-19 in renal transplant recipients

Researchers explore neurological manifestations among long COVID patients

Study demonstrates how pan-sarbecovirus ORF7a protein plays a role in evading host immunity

Systemic inflammation triggered by SARS-CoV-2 found to cause human testicular injury

Study investigates long-range RNA-RNA interactions of SARS-CoV-2

Omicron BA.1 breakthrough infection in vaccinated individuals recall memory B cells to confer immunity

Resistance of Russian Rhinolophus bats containing ACE2-dependent sarbecoviruses to COVID-19 vaccines

Is covid ‘under control’ in the US? Experts say yes

What is the association between body fat and COVID-19?

Long-term follow-up of young people with COVID-19 vaccine myocarditis

How effective are live-attenuated SARS-CoV-2 vaccines?

Are we consuming microplastics through take-out food?

Common germline variants of APOE contribute to differential COVID-19 outcomes

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

Study of 9 million Swedes shows rapidly declining effectiveness of COVID vaccines against Omicron

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