Intensive Care News and Research

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Hydroxychloroquine combined with azithromycin and abnormal heart rhythms in COVID-19 patients

A new study shows that the initially lauded combination of drugs against COVID-19 - Hydroxychloroquine and Chloroquine combined with azithromycin, could lead to abnormal and life-threatening heart rhythms. In patients hospitalized with the novel coronavirus infection or SARS CoV-2, this combination can lead to prolonged QT interval as can be detected on ECG.

3 May 2020

Low molecular weight heparins inhibit SARS-CoV-2 cell invasion

A recent paper available on the preprint server bioRxiv* reports preliminary data on the ability of low molecular weight heparins to interact with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), elicit structural changes in its key proteins and subsequently halt cell invasion.

3 May 2020

High blood pressure drugs found to be safe for COVID-19 patients

Despite concerns expressed by some experts, common high blood pressure drugs did not increase the risk of contracting COVID-19 - or of developing severe disease - in a study of 12,594 patients.

3 May 2020

Hospitalized smokers six times more likely to quit with combination treatment, study finds

New research led by University of South Australia has found that smokers who receive the medication varenicline tartrate combined with Quitline counseling following a period of hospitalization due to a tobacco-related illness are six times more likely to quit smoking than those who attempt to stop without support.

2 May 2020

South African COVID-19 lockdown may not avert outbreak

The study investigated the effect of the various interventions in South Africa on the outbreak, analyzing trends in South Africa before and after the national lockdown, which started on March 27, 2020. Africa has so far reported over 38,000 cases, a small number compared to the 3.25 million global cases as of April 30, 2020. South Africa has reported over 5,600, with Egypt and Morocco close behind.

30 Apr 2020

New clinical trial to assess whether hypertension drug may reduce COVID-19 severity

Researchers at University of California San Diego School of Medicine have launched a clinical trial to investigate whether a drug approved for treating high blood pressure, heart failure and diabetic kidney disease might also reduce the severity of COVID-19 infections, lowering rates for intensive care unit admissions, the use of mechanical ventilators and all-cause mortality.

30 Apr 2020

AHA statements recommend best practice scenario to care for patients with heart failure

Treatment for heart failure should take into consideration a patient's social determinants of health - their overall living environment, socio-economic status, as well as the needs of unpaid family caregivers, according to two new scientific statements from the American Heart Association, published simultaneously today in the Association's flagship journal Circulation.

30 Apr 2020

New physiotherapy guidelines to improve long-term physical function and recovery from COVID-19

New physiotherapy guidelines are targeting COVID-19 patient recovery for respiratory management, exercise and mobilisation in acute hospital wards and Intensive Care Units.

30 Apr 2020

Temple University Hospital is offering COVID-19 clinical trials, investigational treatments options

Temple University Hospital is now participating in a variety of clinical trials that are testing investigational treatment options for patients diagnosed with the novel coronavirus, or COVID-19.

30 Apr 2020

Arthritis drug assessed as potential treatment for COVID-19-related pneumonia

UC San Diego Health has launched a Phase III clinical trial, part of a global effort, to assess whether a medication used to treat rheumatoid arthritis and other inflammatory disorders might also have therapeutic value for COVID-19 patients who have developed or at high risk of developing serious lung damage from SARS-CoV-2 infections.

29 Apr 2020

Low levels of vitamin D may be linked to severe COVID-19

A new observational study from the United States indicates that vitamin D insufficiency may play a significant role in the progression of coronavirus disease (COVID-19). The research titled 'Vitamin D Insufficiency is Prevalent in Severe COVID-19' is available on the preprint server medRxiv.Study shows that low levels of vitamin D may be linked to severe COVID-19

29 Apr 2020

New guidance statement for treating stroke patients in the era of COVID-19

In an effort to mitigate the spread of COVID-19 and to optimize allocation of healthcare resources, researchers are improving ways to treat patients with acute large vessel occlusion strokes in a safe manner that also better protects health care workers.

29 Apr 2020

Critical Care experts share roadmap for meeting challenges posed by COVID-19 pandemic

Hospitals facing a growing population of COVID-19 cases need a coordinated approach with a multidisciplinary team to increase efficiency, conserve PPE and protect staff.

29 Apr 2020

Study with twins shows COVID-19 symptoms have genetic contribution

A new study published on the preprint server medRxiv from King's College, London, suggests that an individual's genetic makeup may contribute to how much a person is likely to be affected by COVID-19, or whether they are likely to be infected at all.

29 Apr 2020

Men are twice more likely to die of COVID-19 than women

There have been studies that have revealed that men are more likely to get more severe symptoms from COVID-19 disease and also more likely to die from complications of the disease. A new study corroborates these findings. The study titled, “Gender differences in patients with COVID-19: Focus on severity and mortality,” is published in the latest issue of the journal Frontiers in Public Health.

29 Apr 2020

COVID-19 could be causing potentially fatal inflammatory disease in children, doctors warn

Since the emergence of the coronavirus disease (COVID-19) in China in December 2019, health experts have cautioned that the disease is particularly serious in high-risk populations, including older adults, those with underlying diseases, and those who are immunocompromised. Now, doctors in the United Kingdom warn of a rare and severe inflammatory disease in children with COVID-19.

28 Apr 2020

How hospitals can prepare for an influx of COVID-19 cases

Hospitals and healthcare systems worldwide are overwhelmed, with many facilities full of patients requiring emergency care for coronavirus disease (COVID-19) that is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 disease causes severe respiratory illness in patients, with some needing mechanical ventilation.

28 Apr 2020

UTHealth experts successfully treat 3-week-old infant with severe COVID-19

In one of the first reported cases of its kind, a 3-week-old infant in critical condition recovered from COVID-19 due to rapid recognition and treatment by physicians from McGovern Medical School at The University of Texas Health Science Center at Houston/

28 Apr 2020

Boston Children's Hospital launches two-pronged study of COVID-19 in children

Boston Children's Hospital has launched a two-pronged study of COVID-19 disease among children and youth up to age 25 across the country, with $2.1 million in funding from the Centers for Disease Control and Prevention.

28 Apr 2020

New nasopharyngeal swabs move into human trials for COVID-19

Researchers at the Wyss Institute at Harvard University, in collaboration with healthcare, research, and industrial partners, have designed a new, fully injection-molded nasopharyngeal swab that can be manufactured quickly and inexpensively at high volume to help address the nationwide and international shortage of swabs for COVID-19 testing and research.

28 Apr 2020

Intensive Care News and Research

Hydroxychloroquine combined with azithromycin and abnormal heart rhythms in COVID-19 patients

Low molecular weight heparins inhibit SARS-CoV-2 cell invasion

High blood pressure drugs found to be safe for COVID-19 patients

Hospitalized smokers six times more likely to quit with combination treatment, study finds

South African COVID-19 lockdown may not avert outbreak

New clinical trial to assess whether hypertension drug may reduce COVID-19 severity

AHA statements recommend best practice scenario to care for patients with heart failure

New physiotherapy guidelines to improve long-term physical function and recovery from COVID-19

Temple University Hospital is offering COVID-19 clinical trials, investigational treatments options

Arthritis drug assessed as potential treatment for COVID-19-related pneumonia

Low levels of vitamin D may be linked to severe COVID-19

New guidance statement for treating stroke patients in the era of COVID-19

Critical Care experts share roadmap for meeting challenges posed by COVID-19 pandemic

Study with twins shows COVID-19 symptoms have genetic contribution

Men are twice more likely to die of COVID-19 than women

COVID-19 could be causing potentially fatal inflammatory disease in children, doctors warn

How hospitals can prepare for an influx of COVID-19 cases

UTHealth experts successfully treat 3-week-old infant with severe COVID-19

Boston Children's Hospital launches two-pronged study of COVID-19 in children

New nasopharyngeal swabs move into human trials for COVID-19

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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