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CellDetect urine test for detecting bladder cancer meets primary endpoint in multi-center clinical study

BioLight Life Sciences Investments Ltd., a firm that invests in, manages and commercializes biomedical innovations in ophthalmology and cancer diagnostics, announced today that a blinded, multi-center clinical study of the CellDetect non-invasive test for detecting bladder cancer in urine, successfully achieved the study's primary endpoint for effectively detecting the recurrence of bladder cancer in subjects with a history of the disease.

3 Feb 2015

Mesothelioma Victims Center implores US homeowners to understand the potential hazards of asbestos

The Mesothelioma Victims Center is urging all US homeowners to familiarize themselves with the dangers of exposure to asbestos in any home constructed with the material as there could be a remote possibility of developing a malignant form of cancer called mesothelioma.

2 Feb 2015

Survey results shows meningioma survivors more likely to want and intend to have baby

The diagnosis of a brain tumor—even one that's usually "benign" and slow growing such as a meningioma—can be scary.

2 Feb 2015

Damon Runyon Cancer Research Foundation names 15 new Damon Runyon Fellows

The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting innovative early career researchers, named 15 new Damon Runyon Fellows at its fall Fellowship Award Committee review. The recipients of this prestigious, four-year award are outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators across the country.

31 Jan 2015

Breast and lung cancer patients with low levels of TTP protein have poorer prognosis

Moffitt Cancer Center researchers have found that breast and lung cancer patients who have low levels of a protein called tristetraprolin (TTP) have more aggressive tumors and a poorer prognosis than those with high levels of the protein.

31 Jan 2015

Alectinib active against leptomeningeal metastases in ALK-positive NSCLC

Patients with anaplastic lymphoma kinase-rearranged non-small-cell lung cancer who have leptomeningeal metastases may benefit from treatment with the second-generation ALK inhibitor alectinib, a case series suggests.

28 Jan 2015

Lund researchers find new way to identify malignant tumours in children

A research group at Lund University in Sweden has found a new way to identify the most malignant tumours in children. The method involves studying genetic 'micro-variation', rather than the presence of individual mutations.

28 Jan 2015

Novel technique could help identify cancerous tissue during brain tumor surgery

A novel radioguided surgery technique could quickly and effectively identify residual cancer cells during brain tumor surgery, with low radiation exposure for both patients and surgeons. The study, featured in the January 2015 issue of the Journal of Nuclear Medicine, reports that Y-90 DOTATOC, a beta-minus-emitting tracer, can effectively delineate the margins of meningiomas and high-grade gliomas.

28 Jan 2015

Researchers reveal role of epigenetic factors in malignant skin cancer

Melanoma, the most aggressive of all skin cancer strains, is often fatal for patients due to the pronounced formation of metastases. Until now, a melanoma's rampant growth was mainly attributed to genetic causes, such as mutations in certain genes. However, researchers from the University of Zurich now reveal that so-called epigenetic factors play a role in the formation of metastases in malignant skin cancer. This opens up new possibilities for future cancer treatments.

22 Jan 2015

Researchers identify promising new target for developing better therapies for neuroblastoma kids

Researchers at the University of Michigan's C.S. Mott Children's Hospital have identified a promising new target for developing new therapies for kids with high-risk neuroblastoma, according to a new study published in Molecular Cancer Research.

22 Jan 2015

Alzheimer's drug Aricept (donepezil) linked to serious side effects

New warnings have been added to the prescribing information for the Alzheimer's drug Aricept (donepezil) advising of the risk of two rare but potentially serious conditions: muscle breakdown (rhabdomyolysis) and a neurological disorder called neuroleptic malignant syndrome (NMS).

21 Jan 2015

Study: Mutated ATRX gene may serve as much-needed biomarker for rare neuroendocrine tumors

A somatic mutation in the ATRX gene has recently been shown as a potential molecular marker for aggressive brain tumors, such as gliomas, neuroblastomas and pancreatic neuroendocrine tumors. Now, for the first time, researchers at Penn's Abramson Cancer Center have found that the same mutated gene may serve as a much-needed biomarker for the pheochromocytomas and paragangliomas (PCC/PGL) that become malignant.

21 Jan 2015

Researchers invent new imaging system to help detect malignant tissue during surgery

With the goal of making it easier for surgeons to detect malignant tissue during surgery and hopefully reduce the rate of cancer recurrence, scientists have invented a new imaging system that causes tumors to "light up" when a hand-held laser is directed at them.

21 Jan 2015

Researchers identify ten new antibodies that can possibly prevent cancer tumours

Out of a library with billions of artificial antibodies, researchers have identified ten that can possibly prevent cancer tumours from growing.

20 Jan 2015

St. Luke’s offers Frameless Stereotactic Radiosurgery for treatment of brain tumors

Some treatments for brain and spine tumors traditionally have involved restraining a patient with a heavy immobilization device and pins that pierce the skin and embed into the skull to ensure the accuracy and precision of a treatment. Doctors say the pins can add considerable anxiety.

20 Jan 2015

Researchers turn clinical experience in multiple myeloma treatment into instructive review for physicians

Multiple myeloma is a malignant disease characterised by proliferation of clonal plasma cells in the bone marrow and typically accompanied by the secretion of monoclonal immunoglobulins that are detectable in the serum or urine. Increased understanding of the microenvironmental interactions between malignant plasma cells and the bone marrow niche, and their role in disease progression and acquisition of therapy resistance, has helped the development of novel therapeutic drugs for use in combination with cytostatic therapy.

20 Jan 2015

Study unveils genetic architecture that enables parasite to develop antimalarial drug resistance

The largest genome-wide association study to date of the malaria parasite Plasmodium falciparum unveils a complex genetic architecture that enables the parasite to develop resistance to our most effective antimalarial drug, artemisinin. The results could help to improve early detection of emerging artemisinin resistance.

20 Jan 2015

New study characterizes genetic underpinnings of phyllodes tumors

A new study from researchers at the University of Michigan Comprehensive Cancer Center characterizes the genetic underpinnings of a rare type of breast tumor called phyllodes tumors, offering the first comprehensive analysis of the molecular alterations at work in these tumors.

16 Jan 2015

Researchers identify new target that could lead to potential therapies for GBM

Researchers from Virginia Commonwealth University Massey Cancer Center and the VCU Institute for Molecular Medicine have identified a new protein-protein interaction that could serve as a target for future therapies for the most common form of brain cancer, glioblastoma multiforme (GBM).

14 Jan 2015

Intrexon and ZIOPHARM Oncology sign exclusive licensing agreement with MD Anderson

Intrexon Corporation, a leader in synthetic biology and its oncology partner, ZIOPHARM Oncology, today announced a broad exclusive licensing agreement with The University of Texas MD Anderson Cancer Center, including an exclusive sublicensing agreement through MD Anderson for intellectual property developed at the University of Minnesota for the development of non-viral adoptive cellular cancer immunotherapies.

14 Jan 2015

Malignant News and Research

CellDetect urine test for detecting bladder cancer meets primary endpoint in multi-center clinical study

Mesothelioma Victims Center implores US homeowners to understand the potential hazards of asbestos

Survey results shows meningioma survivors more likely to want and intend to have baby

Damon Runyon Cancer Research Foundation names 15 new Damon Runyon Fellows

Breast and lung cancer patients with low levels of TTP protein have poorer prognosis

Alectinib active against leptomeningeal metastases in ALK-positive NSCLC

Lund researchers find new way to identify malignant tumours in children

Novel technique could help identify cancerous tissue during brain tumor surgery

Researchers reveal role of epigenetic factors in malignant skin cancer

Researchers identify promising new target for developing better therapies for neuroblastoma kids

Alzheimer's drug Aricept (donepezil) linked to serious side effects

Study: Mutated ATRX gene may serve as much-needed biomarker for rare neuroendocrine tumors

Researchers invent new imaging system to help detect malignant tissue during surgery

Researchers identify ten new antibodies that can possibly prevent cancer tumours

St. Luke’s offers Frameless Stereotactic Radiosurgery for treatment of brain tumors

Researchers turn clinical experience in multiple myeloma treatment into instructive review for physicians

Study unveils genetic architecture that enables parasite to develop antimalarial drug resistance

New study characterizes genetic underpinnings of phyllodes tumors

Researchers identify new target that could lead to potential therapies for GBM

Intrexon and ZIOPHARM Oncology sign exclusive licensing agreement with MD Anderson

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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