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Amherst neurobiologists awarded grant to study how neurons regulate locomotion

Neurobiologist Gerald Downes, with chemist James Chambers at the University of Massachusetts Amherst and Amherst College neurobiologist Josef Trapani, have been awarded a three-year $824,025 collaborative research grant from the National Science Foundation to study the zebrafish brain to better understand how neurons regulate locomotion.

20 Aug 2015

Researchers find potential targets to improve sleep in patients with fibromyalgia

Fibromyalgia is characterized by chronic pain from no clear source. Patients with fibromyalgia frequently have sleep problems: Their deep sleep brain wave patterns are often disrupted by brain waves that correspond to wakefulness.

20 Aug 2015

Equashield reports record revenue growth, expands production facilities for future growth

Equashield, a leading provider of Closed System Transfer Devices (CSTDs) for safe and simple handling of hazardous drugs, today announced a more than doubling of year-over-year revenue.

19 Aug 2015

PHD1 inhibition may have therapeutic potential for colorectal cancer

Scientists at VIB and KU Leuven have shown that blocking the PHD1 oxygen sensor hinders the activation of p53, a transcription factor that aids colorectal cancer (CRC) cells in repairing themselves and thus resisting chemotherapy. Chemotherapy resistance remains a major clinical issue in the treatment of CRC. These findings indicate that PHD1 inhibition may have valuable therapeutic potential. The study was published in the leading medical journal EMBO Molecular Medicine, which features molecular biology-driven research.

19 Aug 2015

AbbVie’s subsidiary to acquire United Therapeutics’ Rare Pediatric Disease Priority Review Voucher

United Therapeutics Corporation announced today that it has entered into an agreement to sell its Rare Pediatric Disease Priority Review Voucher (PPRV) to a subsidiary of AbbVie Inc.

19 Aug 2015

EnGeneIC begins Phase 1 Tailored-EDV trial for advanced solid tumor

EnGeneIC Ltd., an emerging biopharmaceutical company focused on developing its proprietary EDV™ nanocell platform for the targeted delivery of cancer therapeutics, today announced that the first patient has been dosed in its Phase 1 Tailored-EDV trial. The trial is being conducted at the Northern Cancer Institute in Sydney, Australia.

19 Aug 2015

Synthorx employs synthetic DNA technology to produce proteins containing novel amino acids

Synthorx Inc. announced today that the company has employed its proprietary protein expression system to successfully produce proteins containing novel amino acids. Using a semi-synthetic DNA template (containing the synthetic base pair X and Y), Synthorx scientists were able to produce RNA containing X and Y, which was used with an otherwise fully natural biological system, to efficiently direct the incorporation of multiple novel amino acids at different sites in proteins.

19 Aug 2015

Researchers refine breast cancer risk model to give more accurate assessment

A national risk model that gauges a woman's chance of developing breast cancer has been refined to give a more accurate assessment. The revised figures, based on data from more than one million patients, reveal a 300 percent increase in a subset of women whose five-year risk is estimated at 3 percent or higher.

19 Aug 2015

Early exposure to inflammatory cytokines can paralyze CD4 T cells

In a discovery that is likely to rewrite immunology text books, researchers at UC Davis have found that early exposure to inflammatory cytokines, such as interleukin 2, can "paralyze" CD4 T cells, immune components that help orchestrate the body's response to pathogens and other invaders.

19 Aug 2015

Johns Hopkins scientists develop novel fish embryo technique to identify potential new treatments for diabetes

In experiments with 500,000 genetically engineered zebrafish embryos, Johns Hopkins scientists report they have developed a potentially better and more accurate way to screen for useful drugs, and they have used it to identify 24 drug candidates that increase the number of insulin-producing cells in the pancreas.

19 Aug 2015

MRI scanners can steer cell-based, tumour busting therapies to exact target sites in the body

Scientists from the University of Sheffield have discovered MRI scanners, normally used to produce images, can steer cell-based, tumour busting therapies to specific target sites in the body.

19 Aug 2015

Scientists identify new pathway that may protect brain from Alzheimer's disease

It is a hallmark of Alzheimer's disease: Toxic protein fragments known as amyloid-β clumped together between neurons in a person's brain.

19 Aug 2015

NIH grants Clinical and Translational Science Award to UC San Diego

The Clinical and Translational Research Institute (CTRI) at University of California, San Diego has received a five-year Clinical and Translational Science Award (CTSA) for approximately $52 million from the National Center for Advancing Translational Science, part of the National Institutes of Health.

19 Aug 2015

Hi-Tech acquires LG Sciences brand of Sports Nutrition and Bodybuilding products

Hi-Tech Pharmaceuticals, a leading global provider of Sports Nutrition, Weight loss products, and Contract Manufacturing services, and LG Sciences, one of the premier Sports Nutrition and Bodybuilding brands in the United States, today announced that Hi-Tech has acquired LG Sciences brand of Sports Nutrition products and Bodybuilding products.

18 Aug 2015

Researchers describe central role of mTOR in ageing and age-related diseases

For some, TOR may bring to mind a Celtic mountain or perhaps an Internet privacy group. In the world of molecular biology it's a cellular pathway that's found in everything from yeast to mammals.

18 Aug 2015

NCI-MATCH phase II precision medicine trial opens through ECOG-ACRIN

The National Cancer Institute-Molecular Analysis for Therapy Choice (NCI-MATCH) phase II precision medicine trial, known to doctors as trial EAY131, is open through the ECOG-ACRIN Cancer Research Group.

18 Aug 2015

FSU study reveals new method for treating diabetes

A new Florida State University study is changing how researchers look at diabetes research and the drugs used to treat the disease.

18 Aug 2015

New research explores underlying mechanisms by which bacteria acquire antibiotic resistance genes

A scientific peek into bacteria boudoirs is revealing how "sex" among disease-causing microbes can lead different species or strains to become resistant to antibiotic medications.

18 Aug 2015

Growing availability of heroin changing the face of opiate addiction in the U.S.

The growing availability of heroin, combined with programs aimed at curbing prescription painkiller abuse, may be changing the face of opiate addiction in the U.S., according to sociologists.

18 Aug 2015

Researchers report increasing disparities between resource inputs, outcomes in biomedical research

As more money has been spent on biomedical research in the United States over the past 50 years, there has been diminished return on investment in terms of life expectancy gains and new drug approvals, two Johns Hopkins Bloomberg School of Public Health researchers say.

18 Aug 2015

Drugs News and Research

Amherst neurobiologists awarded grant to study how neurons regulate locomotion

Researchers find potential targets to improve sleep in patients with fibromyalgia

Equashield reports record revenue growth, expands production facilities for future growth

PHD1 inhibition may have therapeutic potential for colorectal cancer

AbbVie’s subsidiary to acquire United Therapeutics’ Rare Pediatric Disease Priority Review Voucher

EnGeneIC begins Phase 1 Tailored-EDV trial for advanced solid tumor

Synthorx employs synthetic DNA technology to produce proteins containing novel amino acids

Researchers refine breast cancer risk model to give more accurate assessment

Early exposure to inflammatory cytokines can paralyze CD4 T cells

Johns Hopkins scientists develop novel fish embryo technique to identify potential new treatments for diabetes

MRI scanners can steer cell-based, tumour busting therapies to exact target sites in the body

Scientists identify new pathway that may protect brain from Alzheimer's disease

NIH grants Clinical and Translational Science Award to UC San Diego

Hi-Tech acquires LG Sciences brand of Sports Nutrition and Bodybuilding products

Researchers describe central role of mTOR in ageing and age-related diseases

NCI-MATCH phase II precision medicine trial opens through ECOG-ACRIN

FSU study reveals new method for treating diabetes

New research explores underlying mechanisms by which bacteria acquire antibiotic resistance genes

Growing availability of heroin changing the face of opiate addiction in the U.S.

Researchers report increasing disparities between resource inputs, outcomes in biomedical research

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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