Angiotensin News and Research

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Angiotensin is an oligopeptide in the blood that causes vasoconstriction, increased blood pressure, and release of aldosterone from the adrenal cortex. It is a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays an important role in the renin-angiotensin system.

Non-opioid drug shows promise for treating pain by targeting receptors on immune cells

Faced with the epidemic of opioid addiction, researchers have been charged with finding other strategies to treat pain. Their efforts largely have focused on nerve cells that transmit pain signals to the spinal cord and brain.

6 Jul 2018

Study suggests proteinuria lowering as important target in managing pediatric CKD

In a study of children with chronic kidney disease, blood pressure medications reduced protein excretion in the urine, which was linked with a lower risk of disease progression.

22 Jun 2018

Fewer women meet eligibility criteria for clinical trial of heart failure drugs, study finds

Clinical trial enrolment favors men, according to a study presented today at Heart Failure 2018 and the World Congress on Acute Heart Failure, a European Society of Cardiology congress. The study found that fewer women meet eligibility criteria for trials of heart failure medication.

28 May 2018

Pfizer announces Phase 3 study results of LYRICA Oral Solution CV for pediatric epilepsy patients

Pfizer Inc. announced today positive top-line results of a Phase 3 study examining the use of LYRICA® Oral Solution CV as adjunctive therapy for partial onset seizures in pediatric epilepsy patients one month to less than four years of age.

17 May 2018

UH professor receives NIH grant to protect kidneys from obesity

UH professor of pharmacology Tahir Hussain has received $1.6M from the National Institutes of Health to examine a kidney cell that could prevent damage from inflammation caused by obesity.

7 May 2018

Experimental compound reduces destructive inflammation to improve stroke outcome

An experimental compound appears to improve stroke outcome by reducing the destructive inflammation that can continue months after a stroke, scientists report.

20 Apr 2018

Study reveals unexpected mechanism that induces thirst after alcohol or sugar exposure

Why does drinking alcohol or consuming sugar make us thirsty? An international study of mice in Texas and humans in Europe reveals an unexpected anti-dehydration mechanism.

12 Apr 2018

Researchers uncover specific gene region in hypertension

Genes encode proteins and proteins dictate cell function. Therefore, the thousands of genes expressed in a cell determine what that cell can do.

20 Mar 2018

Two types of blood pressure medications linked to increased variability, higher risk of death

Two types of blood pressure medications - alpha blockers and alpha 2 agonist - show increased variability in blood pressure measurements between doctor visits, which is associated with an increased risk of death, according to new research from the Intermountain Medical Center Heart Institute in Salt Lake City.

13 Mar 2018

Weekend admissions linked to excess mortality risk among young heart attack patients

Young heart attack patients are twice as likely to die if they are admitted to hospital during the weekend compared to a weekday, according to an Italian study in more than 80,000 patients presented today at Acute Cardiovascular Care 2018.

5 Mar 2018

Study finds Ramadan fasting to be safe for heart failure patients

Ramadan fasting can be safe for patients with heart failure, according to research presented today at the 29th Annual Conference of the Saudi Heart Association, held 1 to 3 March in Riyadh, Saudi Arabia.

1 Mar 2018

Blood pressure and cholesterol lowering drugs do not negatively affect erectile function, study says

New study provides reassurance for men taking blood pressure and cholesterol modifying medications, reports the Canadian Journal of Cardiology.

29 Jan 2018

Arterial stiffness improves with high doses of vitamin D supplementation, study finds

In just four months, high-doses of vitamin D reduce arterial stiffness in young, overweight/obese, vitamin-deficient, but otherwise still healthy African-Americans, researchers say.

2 Jan 2018

FDA approves drug to increase blood pressure in adults with septic or distributive shock

The U.S. Food and Drug Administration today approved Giapreza (angiotensin II) injection for intravenous infusion to increase blood pressure in adults with septic or other distributive shock.

21 Dec 2017

Oncologists find new biomarker for breast cancer having poor prognosis

With the support of the FWF, an oncologist found a biomarker for breast cancer having a poor prognosis and developed two viable methods to detect it in tissue samples.

22 Nov 2017

Cancer drugs may offer new way to control high blood pressure

Drugs designed to halt cancer growth may offer a new way to control high blood pressure (hypertension), say Georgetown University Medical Center investigators.

20 Nov 2017

Researchers uncover link between abdominal aortic aneurysm and dysregulated tryptophan metabolism

Researchers have found a link between dysregulated tryptophan metabolism and abdominal aortic aneurysm, a life-threatening vascular disease, according to a new study led by Georgia State University.

13 Nov 2017

Recommendations to prevent heart failure hospitalizations

Heart failure (HF) affects approximately 5.7 million adults in the United States according to the Centers for Disease Control and Prevention. If not properly managed, HF can lead to frequent hospitalizations.

10 Nov 2017

Topical gel made from blood pressure pills holds great promise in healing chronic wounds

An international team of researchers led by Johns Hopkins has shown that a topical gel made from a class of common blood pressure pills that block inflammation pathways speeds the healing of chronic skin wounds in mice and pigs.

1 Nov 2017

Study shows Healthy Days as valid method to evaluate overall population health

Humana Inc. today announced results from a study that found a relationship between patient-reported, health-related quality of life and multiple objective measures of health in elderly Medicare Advantage patients with chronic conditions.

28 Oct 2017