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A novel 3D-printed lab-on-a-chip device concurrently detects SARS-CoV-2 nucleic acid and anti-SARS-CoV-2 antibodies in saliva

Researchers described the development and applications of a 3D-printed lab-on-a-chip device that quickly detected the presence of SARS-CoV-2 in patient's saliva.

10 Aug 2022

A broad sarbecovirus-neutralizing antibody cocktail

Researchers present a rational approach for identifying SARS-CoV-2 receptor-binding domain-targeted broad neutralizing antibody cocktails.

9 Aug 2022

MIT researchers develop an easy-to-use test to predict Covid-19 immunity

Most people in the United States have some degree of immune protection against Covid-19, either from vaccination, infection, or a combination of the two. But, just how much protection does any individual person have?

9 Aug 2022

Research paves the way for therapies to treat or delay preterm labor

Researchers have identified a cause of preterm labor, an enigma that has long challenged researchers. New research published in The Journal of Physiology suggests a protein, called Piezo1, is responsible for regulating the behavior of the uterus.

9 Aug 2022

Double mRNA COVID-19 vaccination found to increase SARS-CoV-2 variant recognition

Researchers evaluated the impact of double BNT162b2 messenger ribonucleic acid (mRNA) vaccination in recognition of SARS-CoV-2 variants of concern.

9 Aug 2022

The neutralizing activity of a panel of 482 human monoclonal antibodies against Omicron BA.4 and BA.5

Researchers demonstrated differential utilization of the B cell germlines and SARS-CoV-2 spike protein epitopes by cross-neutralizing antibodies in infected, vaccinated and individuals with hybrid immunity.

9 Aug 2022

How does the interval between the 1st and 2nd BNT162b2 doses impact the neutralization breadth and potency against variants of concern?

Scientists explored the influence of SARS-CoV-2 extended gap vaccination on the variants of concern neutralization.

9 Aug 2022

Aldosterone may increase risk of kidney failure in patients with chronic kidney disease

A steroid hormone called aldosterone is linked to an increased risk of kidney failure in patients with chronic kidney disease (CKD), according to a study published in the European Heart Journal today (Tuesday).

8 Aug 2022

New enzyme-based biosensor may aid in rapid disease screening and metabolism assessment

Scientists from the Tokyo Medical and Dental University\ introduce an easy method for manufacturing biosensors made from electrospun polymers.

8 Aug 2022

COVID-19 vaccination increases antibodies in breast milk significantly

Anti-SARS-CoV-2 antibodies in breast milk capable of neutralizing both an early pandemic SARS-CoV-2 isolate and Omicron variant.

8 Aug 2022

Inhaled aprotinin found to reduce viral load in mild-to-moderate COVID-19

A recent paper describes the use of aprotinin, a protease inhibitor that works across several pathways, to reduce the severity of COVID-19.

8 Aug 2022

Research progress on the three-dimensional interaction between virus and host genome

A recent study reviewed the current progress on 3D interactions between host and viral genomes.

8 Aug 2022

Fatigue and headache among the most common symptoms following COVID-19 infections

Fatigue and headache were the most common symptoms reported by individuals an average of more than four months out from having COVID-19, investigators report.

8 Aug 2022

Assessing immunization capacity of vaccine platforms with DNA origami harboring SARS-CoV-2 receptor binding domain

Researchers demonstrated that vaccine frameworks containing deoxyribonucleic acid (DNA) origami possessing SARS-CoV-2 receptor-binding domain induce strong protective immunity.

8 Aug 2022

How can we map the human genetic architecture of COVID-19 across all ancestry groups?

In a new study, researchers formed the COVID-19 host genetics initiative to compile a genome-wide association meta-analysis of 60 studies from 25 countries.

8 Aug 2022

NIH researchers develop three-dimensional structure of twinkle protein

Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases.

5 Aug 2022

Saliva-based self-testing platform detects SARS-CoV-2 with the same level of sensitivity as PCR tests

PCR tests, also called molecular tests or nucleic acid tests, are considered the gold standard in detecting the presence of SARS-CoV-2, the virus that gives rise to COVID-19.

5 Aug 2022

New method can modify an entire substance class of medically relevant natural products

The use of the element fluorine to modify active substances is an important tool in modern drug development.

5 Aug 2022

Gut microbiota-derived metabolites offer protection against SARS-CoV-2

A new study investigated how the gut microbiome confers immunity to mammalian hosts against SARS-CoV-2 intranasal infection by generating short-chain fatty acids.

5 Aug 2022

Study identifies broad-spectrum antibody that neutralizes SARS-CoV-2 variants of concern

Scientists have described the identification and therapeutic evaluation of an antibody that broadly neutralizes major variants of SARS-CoV-2, including the alpha, beta, delta, and omicron variants.

5 Aug 2022

Enzyme News and Research

A novel 3D-printed lab-on-a-chip device concurrently detects SARS-CoV-2 nucleic acid and anti-SARS-CoV-2 antibodies in saliva

A broad sarbecovirus-neutralizing antibody cocktail

MIT researchers develop an easy-to-use test to predict Covid-19 immunity

Research paves the way for therapies to treat or delay preterm labor

Double mRNA COVID-19 vaccination found to increase SARS-CoV-2 variant recognition

The neutralizing activity of a panel of 482 human monoclonal antibodies against Omicron BA.4 and BA.5

How does the interval between the 1st and 2nd BNT162b2 doses impact the neutralization breadth and potency against variants of concern?

Aldosterone may increase risk of kidney failure in patients with chronic kidney disease

New enzyme-based biosensor may aid in rapid disease screening and metabolism assessment

COVID-19 vaccination increases antibodies in breast milk significantly

Inhaled aprotinin found to reduce viral load in mild-to-moderate COVID-19

Research progress on the three-dimensional interaction between virus and host genome

Fatigue and headache among the most common symptoms following COVID-19 infections

Assessing immunization capacity of vaccine platforms with DNA origami harboring SARS-CoV-2 receptor binding domain

How can we map the human genetic architecture of COVID-19 across all ancestry groups?

NIH researchers develop three-dimensional structure of twinkle protein

Saliva-based self-testing platform detects SARS-CoV-2 with the same level of sensitivity as PCR tests

New method can modify an entire substance class of medically relevant natural products

Gut microbiota-derived metabolites offer protection against SARS-CoV-2

Study identifies broad-spectrum antibody that neutralizes SARS-CoV-2 variants of concern

Measuring Drug-Target Residence Times with Biochemical Assays eBook

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