Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Scientists aim to revolutionize asthma treatment by replacing inhalers with new drug

A common treatment for asthma, which is the most prevalent chronic childhood disease, requires use of an inhaler. But a big problem with inhalers, used to deliver steroids and other drugs in an aerosol form, is that children often don't operate them properly.

10 May 2017

Researchers discover that microRNA can prevent excessive intestinal inflammation

An international team of researchers has discovered that a microRNA produced by certain white blood cells can prevent excessive inflammation in the intestine.

9 May 2017

Study findings could help identify treatments for balding and hair graying

Researchers at the UT Southwestern Medical Center have discovered the cells that are directly responsible for hair growth and the mechanism that causes gray hair. The study results could help in identifying feasible treatments for balding and hair graying.

9 May 2017

Novel nanoscale molecular slingshot could ‘shoot’ and deliver drugs at precise disease locations

An international team of researchers from the University of Rome Tor Vergata and the University of Montreal has reported, in a paper published this week in Nature Communications, the design and synthesis of a nanoscale molecular slingshot made of DNA that is 20,000 times smaller than a human hair.

9 May 2017

UT Southwestern researchers uncover mechanism linked to balding and hair graying

UT Southwestern Medical Center researchers have identified the cells that directly give rise to hair as well as the mechanism that causes hair to turn gray - findings that could one day help identify possible treatments for balding and hair graying.

9 May 2017

Study reveals role of good-guy protein in initiating and maintaining cancer

Under normal conditions, the CHD4 protein is one of the good guys: it stops cells from transcribing faulty DNA, thereby eliminating potential mutation. But in colon cancer and perhaps other kinds of cancer as well, it appears that this protein becomes a kind of double agent, working for the enemy.

9 May 2017

Study findings shed new light on evolution and interaction of ancient proteins

How did protein interactions arise and how have they developed? In a new study, researchers have looked at two proteins which began co-evolving between 400 and 600 million years ago.

9 May 2017

Researchers develop fast algorithm that provides new insights into protein evolution

Understanding evolution is one of the cornerstones of biology - evolution is, in fact, the sole explanation for life's diversity on our planet.

9 May 2017

Study findings suggest how progranulin deficiency causes frontotemporal dementia

In a recent study in Human Molecular Genetics, researchers from VIB and KU Leuven led by prof. Philip Van Damme, reveal a novel function for progranulin in lysosomes: it acts as chaperone of the lysosomal protease cathepsin D. The results were obtained in collaboration with Prof. Paul Saftig from the University of Kiel.

8 May 2017

Choice of fat causes distinct epigenetic changes in human adipose tissue, study shows

Previous research has demonstrated that saturated fat is more fattening and less muscle building than polyunsaturated fats. A new study shows that the choice of fat causes epigenetic changes which in turn could contribute to differences in fat storage.

8 May 2017

Study uncovers potential new therapeutic targets for HCV infections

An international study led by researchers at Monash University' Biomedicine Discovery Institute (BDI) has shone light on the way the Hepatitis C Virus (HCV) hijacks the communication systems in the host cells it infects, uncovering potential new therapeutic targets for the disease.

8 May 2017

Machine learning algorithm can help predict progression of age-related macular degeneration

Scientists have demonstrated that a machine learning algorithm, using images of patients' retinas obtained over time, can predict the critical moment when early or intermediate age-related macular degeneration (AMD) will progress into severe AMD.

8 May 2017

Obese women may get less dangerous form of preeclampsia, study suggests

Despite having higher rates of preeclampsia, a dangerous high-blood pressure disorder of late pregnancy, obese women may be less than half as likely to suffer strokes, seizures, and other serious complications of the disorder. The

5 May 2017

Study shows how influenza A hijacks human cellular machinery to replicate

Much is known about flu viruses, but little is understood about how they reproduce inside human host cells, spreading infection. Now, a research team headed by investigators from the Icahn School of Medicine at Mount Sinai is the first to identify a mechanism by which influenza A, a family of pathogens that includes the most deadly strains of flu worldwide, hijacks cellular machinery to replicate.

5 May 2017

FDA approves new AML drug after clinical testing at Dana-Farber

A targeted drug whose clinical testing was led by Richard Stone, MD, of Dana-Farber Cancer Institute, has become the first new treatment for newly diagnosed acute myeloid leukemia (AML) in more than 25 years.

5 May 2017

Researchers pinpoint gene that plays crucial role in formation of neural tube defects

Researchers have identified a gene that plays a key role in the formation of neural tube defects, a problem commonly found in infants of pregnant women with diabetes.

5 May 2017

Researchers discover new defense mechanism against bacteria during wound healing

Researchers in dermatology at Lund University in Sweden believe they have cracked the mystery of why we are able to quickly prevent an infection from spreading uncontrollably in the body during wounding. They believe this knowledge may be of clinical significance for developing new ways to counteract bacteria.

5 May 2017

Scientists identify RIOK1 enzyme as new target for cancer therapy

Dr. Florian Weinberg, from Prof. Dr. Tilman Brummer's research group at the Institute of Molecular Medicine and Cell Research of the University of Freiburg, joined forces with scientists from the Departments of Clinical Pathology and Medicine I of the University Medical Centre Freiburg and the Kinghorn Cancer Centre/Garvan Insitute in Australia in an international team that has identified a new target for cancer therapy.

5 May 2017

Recurrence of HPV-negative HNSCC after radiation therapy linked to high tumor levels of PD-L1 protein

Recurrence of head and neck squamous cell carcinoma (HNSCC) negative for human papillomavirus (HPV) following radiation therapy was associated with high tumor levels of the protein PD-L1.

5 May 2017

TSRI scientists uncover regulatory machinery underlying the function of cancer protein

Despite intense research, there's been much confusion regarding the exact role of a protein in a critical cancer-linked pathway. On one hand, the protein is described as a cell proliferation inhibitor, on the other, a cell proliferation activator, a duality that has caused a great deal of scientific head scratching.

5 May 2017

Protein News and Research

Further Reading

Scientists aim to revolutionize asthma treatment by replacing inhalers with new drug

Researchers discover that microRNA can prevent excessive intestinal inflammation

Study findings could help identify treatments for balding and hair graying

Novel nanoscale molecular slingshot could ‘shoot’ and deliver drugs at precise disease locations

UT Southwestern researchers uncover mechanism linked to balding and hair graying

Study reveals role of good-guy protein in initiating and maintaining cancer

Study findings shed new light on evolution and interaction of ancient proteins

Researchers develop fast algorithm that provides new insights into protein evolution

Study findings suggest how progranulin deficiency causes frontotemporal dementia

Choice of fat causes distinct epigenetic changes in human adipose tissue, study shows

Study uncovers potential new therapeutic targets for HCV infections

Machine learning algorithm can help predict progression of age-related macular degeneration

Obese women may get less dangerous form of preeclampsia, study suggests

Study shows how influenza A hijacks human cellular machinery to replicate

FDA approves new AML drug after clinical testing at Dana-Farber

Researchers pinpoint gene that plays crucial role in formation of neural tube defects

Researchers discover new defense mechanism against bacteria during wound healing

Scientists identify RIOK1 enzyme as new target for cancer therapy

Recurrence of HPV-negative HNSCC after radiation therapy linked to high tumor levels of PD-L1 protein

TSRI scientists uncover regulatory machinery underlying the function of cancer protein

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