Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Neuroprotective effects of ginsenoside Rb1 on hippocampal neuronal injury, neurite outgrowth

The main pathological changes of Alzheimer's disease (AD) include amyloid-beta protein-induced hippocampal neuronal injury and neurite outgrowth impairment.

15 Jul 2014

Pfizer to in-license Absorption Systems' BCRP-MDCK cells

Absorption Systems, a leader in novel test systems for drug transporters, announces a license agreement with Pfizer Inc., in which Pfizer will in-license Absorption Systems' BCRP-MDCK cells. This cell line is stably transfected with the human ABCG2 gene, which codes for a protein known as BCRP (breast cancer resistance protein).

15 Jul 2014

New role for cholesterol in activation of cellular signaling pathway that linked to cancer

Everyone knows that cholesterol, at least the bad kind, can cause heart disease and hardening of the arteries. Now, researchers at the University of Illinois at Chicago describe a new role for cholesterol in the activation of a cellular signaling pathway that has been linked to cancer.

15 Jul 2014

Interaction between 2 proteins can be responsible for allergic asthma after eating infected fruit

Researchers at the UPM suggest that the interaction between two proteins can be the responsible for the allergic asthma episodes after eating an infected fruit.

15 Jul 2014

DARPins could revolutionize protein therapeutics

Integrating an INTEGRA VIAFLO 96 multichannel pipette into their high throughput expression facility has enabled Molecular Partners (Zurich, Switzerland) to streamline the discovery and development of a novel class of targeted protein therapeutics termed DARPins.

From INTEGRA Biosciences 15 Jul 2014

New potential avenues to predict and prevent ovarian cancer metastasis

Circulating tumor cells spread ovarian cancer through the bloodstream, homing in on a sheath of abdominal fatty tissue where it can grow and metastasize to other organs, scientists at The University of Texas MD Anderson Cancer Center report in Cancer Cell.

15 Jul 2014

Researchers develop new software to identify severity of cancer

Together with the company Tissuegnostics, the pathologist Lukas Kenner and his colleagues have developed a software that is able to identify cancer cells in tissue sections and demonstrate the presence of specific biomarkers on cells. The overall information provides a precise picture of the disease and leads to the most suitable treatment.

15 Jul 2014

BAI and Novartis determine whether investigational drugs can prevent symptoms of Alzheimer's

Researchers from the Banner Alzheimer's Institute (BAI) today announced a partnership with Novartis in a pioneering medical trial to determine whether two investigational anti-amyloid drugs-an active immunotherapy and an oral medication-can prevent or delay the emergence of symptoms of Alzheimer's in people at particularly high risk for developing the disease at older ages.

15 Jul 2014

Acute glaucoma is largely an inflammatory disease, say researchers

Researchers at the University of California, San Diego School of Medicine and Sun Yat-sen University in China have shown that acute glaucoma in mice is largely an inflammatory disease and that high pressure in the eye causes vision loss by setting in motion an inflammatory response similar to that evoked by bacterial infections.

14 Jul 2014

Study pinpoints molecular cause of cachexia, hints at a potential treatment

New research raises the prospect of more effective treatments for cachexia, a profound wasting of fat and muscle occurring in about half of all cancer patients, raising their risk of death, according to scientists from Dana-Farber Cancer Institute.

14 Jul 2014

New research opens up potential new therapeutic targets for hard-to-treat food allergy

New research in Nature Genetics identifies a novel genetic and molecular pathway in the esophagus that causes eosinophillic esophagitis (EoE), opening up potential new therapeutic strategies for an enigmatic and hard-to-treat food allergy.

14 Jul 2014

Pareto partners with DNA2.0 to develop technology for quick-to-market products

Synthetic biology company Pareto Biotechnologies today announces a technology partnership with global bioengineering leader DNA2.0, enabling Pareto to further develop its technology for quick-to-market products.

14 Jul 2014

Study to understand molecular interplay between Roquin and RNA to treat autoimmune diseases

Scientists at the Helmholtz Zentrum München, the Ludwig-Maximilians University of Munich (LMU) and the Technische Universität München (TUM) have moved an important step closer to understanding molecular mechanisms of autoimmune diseases.

14 Jul 2014

Researchers identify new suppressor of cancer metastasis

Among patients with deadly cancers, more than 90 percent die because of metastatic spread of their disease. Looking to target a key pathway in order to interfere with the processes that lead to tumor spread, a research team led by Irwin H. Gelman, Ph.D., of Roswell Park Cancer Institute (RPCI) has identified a new suppressor of cancer metastasis that may point the way toward development of more effective treatments for prostate cancers and other malignant solid tumors.

14 Jul 2014

Eye exam for beta-amyloid correlates with levels in brain, detects people with Alzheimer's

A decreased ability to identify odors might indicate the development of cognitive impairment and Alzheimer's disease, while examinations of the eye could indicate the build-up of beta-amyloid, a protein associated with Alzheimer's, in the brain, according to the results of four research trials reported today at the Alzheimer's Association International Conference- 2014 (AAIC- 2014) in Copenhagen.

14 Jul 2014

Astrocytes play role in forming inhibitory synapses

Rio de Janeiro, Brazil- In the brains of all vertebrates, information is transmitted through synapses, a mechanism that allows an electric or chemical signal to be passed from one brain cell to another.

11 Jul 2014

New way to protect crops from insect plagues in safe and environmentally responsible way

Using spider toxins to study the proteins that let nerve cells send out electrical signals, Johns Hopkins researchers say they have stumbled upon a biological tactic that may offer a new way to protect crops from insect plagues in a safe and environmentally responsible way.

11 Jul 2014

2D IR spectroscopy reveals intermediate structure during amylin aggregation pathway

Amyloid diseases, such as Alzheimer's disease, type 2 diabetes, cataracts, and the spongiform encephalopathies, all share the common trait that proteins aggregate into long fibers which then form plaques.

11 Jul 2014

Kainos Capital announces acquisition of Unilever's Slim-Fast brand

Kainos Capital, a firm specializing in acquiring and managing food and consumer brands, today announced that it has acquired the Slim-Fast brand from Unilever. Unilever will retain a minority stake in the business. Terms of the transaction were not disclosed.

11 Jul 2014

BrightFocus offers grants to 55 scientists for Alzheimer's disease and vision research

BrightFocus Foundation, a nonprofit organization funding cutting-edge, innovative research on Alzheimer's disease and the vision diseases of glaucoma and macular degeneration, today announced the recipients of new research grant awards, offered to 55 scientists in 19 U.S. states, the District of Columbia, and five foreign countries.

11 Jul 2014

Protein News and Research

Further Reading

Neuroprotective effects of ginsenoside Rb1 on hippocampal neuronal injury, neurite outgrowth

Pfizer to in-license Absorption Systems' BCRP-MDCK cells

New role for cholesterol in activation of cellular signaling pathway that linked to cancer

Interaction between 2 proteins can be responsible for allergic asthma after eating infected fruit

DARPins could revolutionize protein therapeutics

New potential avenues to predict and prevent ovarian cancer metastasis

Researchers develop new software to identify severity of cancer

BAI and Novartis determine whether investigational drugs can prevent symptoms of Alzheimer's

Acute glaucoma is largely an inflammatory disease, say researchers

Study pinpoints molecular cause of cachexia, hints at a potential treatment

New research opens up potential new therapeutic targets for hard-to-treat food allergy

Pareto partners with DNA2.0 to develop technology for quick-to-market products

Study to understand molecular interplay between Roquin and RNA to treat autoimmune diseases

Researchers identify new suppressor of cancer metastasis

Eye exam for beta-amyloid correlates with levels in brain, detects people with Alzheimer's

Astrocytes play role in forming inhibitory synapses

New way to protect crops from insect plagues in safe and environmentally responsible way

2D IR spectroscopy reveals intermediate structure during amylin aggregation pathway

Kainos Capital announces acquisition of Unilever's Slim-Fast brand

BrightFocus offers grants to 55 scientists for Alzheimer's disease and vision research

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