Colon News and Research

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Study provides new insights into early events that shape cancer

A study led by researchers from Brigham and Women's Hospital suggests a new way to trace cancer back to its cell type of origin. By leveraging the epigenome maps produced by the Roadmap Epigenomics Program - a resource of data collected from over 100 cell types - the research team found that the unique genetic landscape of a particular tumor could be used to predict that tumor's cell type of origin.

19 Feb 2015

UT Southwestern scientists identify new biomarker that could optimize chemotherapy response

UT Southwestern Medical Center scientists have identified a new biomarker that could help identify patients who are more likely to respond to certain chemotherapies.

18 Feb 2015

UT Arlington chemist receives NIH's Academic Research Enhancement Award for protein research

A University of Texas at Arlington bio-analytical chemist exploring proteins, their structures and functions by using cutting-edge analytical instrumentation called mass spectrometry has received an Academic Research Enhancement Award from the National Institutes of Health.

18 Feb 2015

Oral pathogen protects different tumor cells from being killed by immune cells

Bacteria that are commonly found in the mouth are often abundant in patients with colon cancer, but the potential role these microbes play in tumor development has not been clear. A study published by Cell Press February 18th in the journal Immunity reveals that the oral pathogen Fusobacterium nucleatum protects a variety of tumor cells from being killed by immune cells.

12 Feb 2015

New Endoscopic Technique

A flexible wide-field endoscope utilising blue excitation light provides label-free contrast of tissue based on fluorescence lifetime imaging of tissue autofluorescence.

10 Feb 2015

Discovery leads to new understanding of cancer metastasis

In a breakthrough in the understanding of how cancer spreads, researchers at the University of Virginia School of Medicine have identified a substance secreted by lung cancer cells that enables them to metastasize, beginning their deadly march to other sites in the body.

10 Feb 2015

Scientists potentially discover new therapeutic targets to halt progression of tumor cells

Chronic inflammation is directly associated with several types of cancer, yet the reasons as to why this happens at a cellular level remain unclear. Now, an international team of scientists led by researchers at The Wistar Institute has identified a multistep process showing not only how these cancers develop but also potentially discovering new therapeutic targets that could halt the formation and progression of tumor cells.

10 Feb 2015

Combination therapies may overcome resistance to targeted cancer drugs

A protein called YAP, which drives the growth of organs during development and regulates their size in adulthood, plays a key role in the emergence of resistance to targeted cancer therapies, according to a new study led by UC San Francisco researchers.

10 Feb 2015

Medicare coverage of CT lung cancer screening can save more lives

Medicare's final decision to cover computed tomography (CT) lung cancer screening gives seniors at high-risk for the disease access to care that can save more lives than any cancer screening test in history.

8 Feb 2015

New study provides better understanding of how stem cells give rise to tumors

Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have discovered a precise stem cell signaling process that can lead to intestinal tumors if disrupted. The findings add to our understanding of how stem cells give rise to tumors and identify specific stem cell molecules that may be targeted to prevent the onset, progression, and recurrence of intestinal cancers.

6 Feb 2015

ECOG-ACRIN Cancer Research Group opens clinical trial for women with newly diagnosed DCIS

In direct response to recommendations made by a National Institutes of Health scientific consensus panel, the ECOG-ACRIN Cancer Research Group announced today the opening of E4112, a clinical trial for women with newly diagnosed ductal carcinoma in situ (DCIS) of the breast who, together with their doctors, will use the results of a magnetic resonance imaging (MRI) exam to determine whether to undergo a lumpectomy or a mastectomy.

6 Feb 2015

Study focuses on two natural approaches to preventing breast cancer

Preventing cancer requires intimate knowledge of how cancer starts, what causes it to grow and flourish, and how to stop it in its tracks. Sometimes this comes in the form of a vaccine (the HPV vaccine for cervical and head and neck cancers), a screening (a colonoscopy for colorectal cancer) or a blood test (the PSA level test for prostate cancer).

5 Feb 2015

New study sheds light on syndrome linked to aggressive pediatric cancer

A new study involving researchers at The University of Nottingham has revealed how children with an aggressive cancer predisposition syndrome experience a never before seen flood of mutations in their disease in just six months.

4 Feb 2015

International community funding can significantly reduce cancer deaths in LMICs by 2030

Increased annual international community funding of US$18 billion globally could save three million lives per year by 2030 and many more in succeeding decades,

3 Feb 2015

Researchers are one step closer to devising an approach to identify pancreatic cancer earlier

Pancreatic cancer affects approximately 46,000 people each year in the United States and ranks fourth among the leading causes of cancer-related deaths. Only about 6 percent of individuals with pancreatic cancer will live five years after their diagnosis.

3 Feb 2015

Researchers reveal new pathway for inhibiting growth of tumor cells tied to BRCA mutations

Inhibiting the action of a particular enzyme dramatically slows the growth of tumor cells tied to BRCA1 and BRCA2 genetic mutations which, in turn, are closely tied to breast and ovarian cancers, according to researchers at NYU Langone Medical Center.

3 Feb 2015

Mathematical models of cancer behavior offer new insights on tumor growth

Hassan Fathallah-Shaykh, M.D., Ph.D., believes that math can transform medicine, and he has the numbers to prove it.

2 Feb 2015

Study discovers microRNA signatures that could predict prognosis, distant metastasis in colorectal cancer

A new study developed at the Center for Gastrointestinal Cancer Research and the Center for Epigenetics, Cancer Prevention and Cancer Genomics at Baylor Research Institute has discovered unique metastasis-specific microRNA signatures in primary colorectal cancers that could predict prognosis and distant metastasis in colorectal cancer.

31 Jan 2015

Damon Runyon Cancer Research Foundation names 15 new Damon Runyon Fellows

The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting innovative early career researchers, named 15 new Damon Runyon Fellows at its fall Fellowship Award Committee review. The recipients of this prestigious, four-year award are outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators across the country.

31 Jan 2015

Breast and lung cancer patients with low levels of TTP protein have poorer prognosis

Moffitt Cancer Center researchers have found that breast and lung cancer patients who have low levels of a protein called tristetraprolin (TTP) have more aggressive tumors and a poorer prognosis than those with high levels of the protein.

31 Jan 2015

Colon News and Research

Study provides new insights into early events that shape cancer

UT Southwestern scientists identify new biomarker that could optimize chemotherapy response

UT Arlington chemist receives NIH's Academic Research Enhancement Award for protein research

Oral pathogen protects different tumor cells from being killed by immune cells

New Endoscopic Technique

Discovery leads to new understanding of cancer metastasis

Scientists potentially discover new therapeutic targets to halt progression of tumor cells

Combination therapies may overcome resistance to targeted cancer drugs

Medicare coverage of CT lung cancer screening can save more lives

New study provides better understanding of how stem cells give rise to tumors

ECOG-ACRIN Cancer Research Group opens clinical trial for women with newly diagnosed DCIS

Study focuses on two natural approaches to preventing breast cancer

New study sheds light on syndrome linked to aggressive pediatric cancer

International community funding can significantly reduce cancer deaths in LMICs by 2030

Researchers are one step closer to devising an approach to identify pancreatic cancer earlier

Researchers reveal new pathway for inhibiting growth of tumor cells tied to BRCA mutations

Mathematical models of cancer behavior offer new insights on tumor growth

Study discovers microRNA signatures that could predict prognosis, distant metastasis in colorectal cancer

Damon Runyon Cancer Research Foundation names 15 new Damon Runyon Fellows

Breast and lung cancer patients with low levels of TTP protein have poorer prognosis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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