Lipids News and Research

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Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The main biological functions of lipids include energy storage, as structural components of cell membranes, and as important signaling molecules.

New imaging tool reveals subtle changes in breast tissue

Purdue University researchers have created a new imaging technology that reveals subtle changes in breast tissue, representing a potential tool to determine a woman's risk of developing breast cancer and to study ways of preventing the disease.

6 Mar 2012

Brain mitochondria are dysfunctional in early-stage Alzheimer's

Mitochondria -- subunits inside cells that produce energy -- have long been thought to play a role in Alzheimer's disease. Now Mayo Clinic researchers using genetic mouse models have discovered that mitochondria in the brain are dysfunctional early in the disease.

1 Mar 2012

UT Southwestern's chairman of pharmacology wins 2012 Rolf Luft Award

Dr. David Mangelsdorf, chairman of pharmacology at UT Southwestern Medical Center, has been awarded the 2012 Rolf Luft Award for research that has advanced understanding of nuclear receptor pathways.

28 Feb 2012

New RNA interference method holds promise for cancer, other diseases

For the past decade, scientists have been pursuing cancer treatments based on RNA interference - a phenomenon that offers a way to shut off malfunctioning genes with short snippets of RNA. However, one huge challenge remains: finding a way to efficiently deliver the RNA.

27 Feb 2012

GSK, Angiochem to develop and commercialize LSD treatments

Angiochem announced today a global collaboration with GlaxoSmithKline (GSK) to discover, develop and commercialize treatments for lysosomal storage diseases.

27 Feb 2012

Study: Diabetes may begin in the gut

Scientists at Washington University School of Medicine in St. Louis have made a surprising discovery about the origin of diabetes. Their research suggests that problems controlling blood sugar - the hallmark of diabetes - may begin in the intestines.

15 Feb 2012

Length of residence in the U.S. increases risk of PTB among Hispanic women

The longer a Hispanic woman lives in the United States, the higher her risk of preterm birth (PTB), with nearly half of PTBs among Hispanic women occurring in those who were born in the U.S.

13 Feb 2012

Heart-healthy Valentine's Day meal tips

Eat your heart out America, for there are foods that actually help the health of your heart. "Years of research has shown that a balanced diet with fruits, vegetables, whole grains, unsaturated fat and lean protein will not only help with weight maintenance, but with overall heart health," said Katie Boles, R.D., L.D.N., clinical dietician with the Brenner FIT Program, at Wake Forest Baptist Medical Center. "Eating a variety of these foods and eating them in moderation is key to a heart-healthy diet."

10 Feb 2012

Negative consequences of maternal obesity can be reversed through exercise

Exercise is the key to overcoming the adverse metabolic effects passed on to offspring by their overweight mothers, with research showing for the first time these effects can be almost completely reversed through physical activity.

10 Feb 2012

New technologies safe and effective for fat removal

For many people, getting rid of excess fat can be a lifelong battle. Whether it is undesirable love handles, excess fat around the knees or flabby upper arms, pockets of fat can be difficult to reduce and sometimes diet and exercise are not enough to make a noticeable difference. Now, dermatologists are finding that the introduction of non-invasive fat removal technologies is opening the door for more people who are not candidates for liposuction to remove stubborn fat, safely and effectively.

8 Feb 2012

Postmenopausal women at higher risk of stroke than they think

A new study by researchers at NYU Langone Medical Center and colleagues found that traditional risk factors for stroke - such as high cholesterol - are not as accurate at predicting risk in postmenopausal women as previously thought. Instead, researchers say doctors should refocus their attention on triglyceride levels to determine which women are at highest risk of suffering a devastating and potentially fatal cardiovascular event.

3 Feb 2012

Specific gene mutation triggers development of NAFLD

A team of scientists from the University of Utah and the University of California at San Francisco has discovered that the mutation of a gene encoding a ketone body transporter triggers accumulation of fat and other lipids in the livers of zebrafish.

1 Feb 2012

Researcher have identified thirty one regions of genome associated with circulating metabolites

In a study to the genetic variance of human metabolism, researchers have identified thirty one regions of the genome that were associated with levels of circulating metabolites, i.e., small molecules that take part in various chemical reactions of human body.

30 Jan 2012

New technique to overcome genetic oddity of P. falciparum

The parasite that causes malaria is a genetic outlier, which has prevented scientists from discovering the functions of most of its genes. Researchers at National Jewish Health and Yale University School of Medicine have devised a technique to overcome the genetic oddity of Plasmodium falciparum, the major cause of human malaria.

27 Jan 2012

Study finds low blood levels of HDL in children with autism

Mystery surrounds autism. Its theories of causes and treatments are as unique and diverse as the people who have it. The same holds true for its symptoms. Scientists and physicians are uncovering more about this disorder every day; many of those studies and findings concentrate on diet.

25 Jan 2012

WSU professors receive NSF grant to develop math model of liver metabolism

Predicting problems in one of the body's most complex organs soon may become easier because of work being done by Wayne State University researchers.

20 Jan 2012

A reliable way to replicate α-synuclein aggregation on cell membranes in Parkinson's disease patients

The accumulation of α-synuclein, a small, negatively charged protein, in neural cells, is one of the hallmarks of Parkinson's disease. It has been suggested that oligomeric α-synuclein causes membranes to become permeable, or to form channels on the outer cell membrane.

19 Jan 2012

UI chemists debunk misconception about amphotericin

With one simple experiment, University of Illinois chemists have debunked a widely held misconception about an often-prescribed drug.

17 Jan 2012

TAMEST honors UT Southwestern scientist with Edith and Peter O'Donnell Award

Dr. Philipp Scherer, director of the Touchstone Center for Diabetes Research at UT Southwestern Medical Center, was recognized today as a rising star in Texas research by The Academy of Medicine, Engineering and Science of Texas.

13 Jan 2012

Nature journal publishes Ember's brown fat biology data

Ember Therapeutics, Inc., a company harnessing breakthroughs in brown fat biology and insulin sensitization to revolutionize the treatment of metabolic disease, today announced the publication of key data supporting its lead brown fat biology program in the journal Nature.

12 Jan 2012