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Researchers identify potential therapeutic target for glioblastoma

A multicenter team of researchers has identified an enzyme key to the survival and spread of glioblastoma cancer cells that is not present in healthy brain cells, making the enzyme a promising therapeutic target.

4 Nov 2014

Moffitt researcher uncovers new approach to treat cancer

The scientific community has made significant strides in recent years in identifying important genetic contributors to malignancy and developing therapeutic agents that target altered genes and proteins. A recent approach to treat cancer called synthetic lethality takes advantage of genetic alterations in cancer cells that make them more susceptible to certain drugs.

31 Oct 2014

Reduced chemotherapy exposure after surgery could decrease overall complications

A study of pediatric patients with hepatoblastoma led by researchers at Children's Hospital Los Angeles (CHLA) suggests an opportunity to reduce chemotherapy in up to 65 percent of patients, which could lead to a decrease in the incidence of adverse effects.

31 Oct 2014

Endemic lung infection compromises lung cancer diagnosis

The accuracy of lung cancer diagnosis using 18F-fluorodeoxyglucose–positron emission tomography may be compromised in areas with endemic infectious lung diseases, research suggests.

30 Oct 2014

Same cell type can give rise to different gliomas

Glioma is a common name for serious brain tumours. Different types of glioma are usually diagnosed as separate diseases and have been considered to arise from different cell types in the brain.

29 Oct 2014

Game theory and the cancer ecosystem: an interview with Professor Pienta, Johns Hopkins

The classic description of game theory was described by the prisoner's dilemma, which is a situation in which two players have two options where the outcome depends on the simultaneous choice made by the other.

29 Oct 2014

Osteros Biomedica initiates MBC-11 phase 1 study in patients with cancer-induced bone disease

Osteros Biomedica Ltd., a joint venture company of Maxwell Biotech Group and MBC Pharma Inc., and formed with the participation of Russian Venture Company announced today that the first cohort of patients has been dosed in a phase 1 study of its drug MBC-11 in patients with cancer-induced bone disease.

28 Oct 2014

Simple blood test may help spot pancreatic cancer

Indiana University cancer researchers have found that a simple blood test might help diagnose pancreatic cancer, one of the most deadly forms of the disease.

28 Oct 2014

Pre-treatment pain intensity predicts survival of patients with head and neck cancer

Pre-treatment pain intensity is an independent survival predictor for patients with head and neck cancer, according to new research published in The Journal of Pain, the peer-reviewed publication of the American Pain Society.

28 Oct 2014

Ludwig researchers discover key mechanism that control plasticity of epithelial cells

Ludwig Oxford researchers have discovered a key mechanism that governs how cells of the epithelia, the soft lining of inner body cavities, shift between a rigid, highly structured and immobile state and a flexible and motile form.

27 Oct 2014

ECMO improves survival, neurological outcomes in patients suffering from cardiac arrest

A new study shows that survival and neurological outcomes for patients in cardiac arrest can be improved by adding extracorporeal membrane oxygenation (ECMO) when performing cardiopulmonary resuscitation (CPR).

21 Oct 2014

NICO, Synaptive Medical join forces to integrate innovative technologies for brain surgery

Indianapolis interventional medical device maker NICO Corporation and Toronto-based 3D visualization leader Synaptive Medical announced today at the Congress of Neurological Surgeons Annual Meeting that they have joined forces to integrate their innovative technologies for brain surgery.

20 Oct 2014

Janssen announces submission of IMBRUVICA sNDA to FDA for WM treatment

Janssen Research & Development, LLC today announced the submission of a supplemental New Drug Application (sNDA) for IMBRUVICA (ibrutinib) to the U.S. Food and Drug Administration by its strategic partner Pharmacyclics, Inc.

20 Oct 2014

New automaton model simulates various scenarios of tumor growth

Cancer constantly wages war on the human body. Battles are won, lost or sometimes end in a stalemate. In pancreatic cancer, this stalemate—known as tumor dormancy—can last up to 25 years before becoming aggressively malignant, a phenomena that is poorly understood.

17 Oct 2014

SOFIE BIOSCIENCES awarded NCI Phase II SBIR contract to develop [18F]FAC PET

SOFIE BIOSCIENCES, a leader in the field of Positron Emission Tomography (PET) imaging, including probes, scanners, and chemistry systems, announced today that the National Cancer Institute has awarded the company a Phase II Small Business Innovation Research (SBIR) contract for approximately $1.5M over two years.

16 Oct 2014

Researchers develop ADNEX test to help doctors diagnose ovarian cancer, choose best treatment

Researchers have devised a new test to help doctors diagnose ovarian tumours and choose the most appropriate treatment.

16 Oct 2014

Ebola outbreak emphasizes the importance of monitoring disease burden in developing countries

A study recently published in the Journal of the American Academy of Dermatology shows that for Ebola, measles, syphilis and many other conditions with skin manifestations the mortality rates are hundreds of times higher in developing countries than they are in developed countries.

16 Oct 2014

Scientists combine new type of nanoparticle with photodynamic therapy to kill cancer cells

An international group of scientists led by Gang Han, PhD, at the University of Massachusetts Medical School, has combined a new type of nanoparticle with an FDA-approved photodynamic therapy to effectively kill deep-set cancer cells in vivo with minimal damage to surrounding tissue and fewer side effects than chemotherapy. This promising new treatment strategy could expand the current use of photodynamic therapies to access deep-set cancer tumors.

16 Oct 2014

Research finding offers new insights into the cause of glioblastoma

Researchers at the University of California, San Diego School of Medicine have identified a new fusion protein found in approximately 15 percent of secondary glioblastomas or brain tumors. The finding offers new insights into the cause of this cancer and provides a therapeutic target for personalized oncologic care.

14 Oct 2014

NCCN publishes 20th annual editions of NCCN Guidelines for Colon and Rectal Cancers

The National Comprehensive Cancer Network has published the 20th annual editions of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Colon and Rectal Cancers, two of the eight original NCCN Guidelines published in November 1996.

10 Oct 2014

Malignant News and Research

Researchers identify potential therapeutic target for glioblastoma

Moffitt researcher uncovers new approach to treat cancer

Reduced chemotherapy exposure after surgery could decrease overall complications

Endemic lung infection compromises lung cancer diagnosis

Same cell type can give rise to different gliomas

Game theory and the cancer ecosystem: an interview with Professor Pienta, Johns Hopkins

Osteros Biomedica initiates MBC-11 phase 1 study in patients with cancer-induced bone disease

Simple blood test may help spot pancreatic cancer

Pre-treatment pain intensity predicts survival of patients with head and neck cancer

Ludwig researchers discover key mechanism that control plasticity of epithelial cells

ECMO improves survival, neurological outcomes in patients suffering from cardiac arrest

NICO, Synaptive Medical join forces to integrate innovative technologies for brain surgery

Janssen announces submission of IMBRUVICA sNDA to FDA for WM treatment

New automaton model simulates various scenarios of tumor growth

SOFIE BIOSCIENCES awarded NCI Phase II SBIR contract to develop [18F]FAC PET

Researchers develop ADNEX test to help doctors diagnose ovarian cancer, choose best treatment

Ebola outbreak emphasizes the importance of monitoring disease burden in developing countries

Scientists combine new type of nanoparticle with photodynamic therapy to kill cancer cells

Research finding offers new insights into the cause of glioblastoma

NCCN publishes 20th annual editions of NCCN Guidelines for Colon and Rectal Cancers

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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