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New drug combination destroys bacterial infection that can be fatal to cystic fibrosis patients

A new treatment developed by researchers at Aston University and Birmingham Children's Hospital has been found to completely kill a bacterial infection that can be deadly to cystic fibrosis patients.

24 Jan 2020

New vaccine against African swine fever appears to be more effective than previous vaccines

Government and academic investigators have developed a vaccine against African swine fever that appears to be far more effective than previously developed vaccines. The research appears this week in the Journal of Virology, a publication of the American Society for Microbiology.

23 Jan 2020

Researchers identify novel cellular entry factor for AAV vector types

Researchers led by a team at Massachusetts Eye and Ear have identified a novel cellular entry factor for adeno-associated virus vector (AAV) types--the most commonly used viral vectors for in vivo gene therapy. AAVs are vectors-or vehicles--that are created from a virus that is made harmless by molecular engineering, and have shown promise transporting genetic therapy treatments to affected tissues.

23 Jan 2020

New method reveals how giant viruses infect amoeba

Host cells infected with giant viruses behave in a unique manner. To gain deeper insight into the infection mechanism of giant viruses, scientists at Tokyo University of Science developed a specialized algorithm that can track the movement of host cells.

23 Jan 2020

Scientists reverse HIV latency, take major scientific step toward curative therapies

Approximately 38 million people are infected with HIV worldwide, about 1.1 million people in the United States. Currently, people with HIV take antiretroviral therapy (ART), which can suppress HIV to undetectable levels in blood, but the virus persists throughout the body in latently infected resting CD4+ T cells.

22 Jan 2020

Johns Hopkins researchers warn of new infectious diseases and death due to global warming

The Journal of Clinical Investigation recently published "Viewpoint" articles by Johns Hopkins University School of Medicine professors who warn that global climate change is likely to unlock dangerous new microbes, as well as threaten humans' ability to regulate body temperature.

From Johns Hopkins Medicine 22 Jan 2020

Injecting nanoparticles into the bloodstream to reduce brain swelling after traumatic brain injury

After a traumatic brain injury, the most harmful damage is caused by secondary swelling of the brain compressed inside the skull. There is no treatment for this.

22 Jan 2020

Study shows how gene therapy may help protect against vision loss in multiple sclerosis

New research by Dorothy P. Schafer, PhD, at the University of Massachusetts Medical School, reveals the molecular process in which synaptic connections in the brain are damaged in multiple sclerosis and how this contributes to neurodegenerative symptoms.

21 Jan 2020

Novel composite could help to reduce foodborne illness outbreaks

A novel composite film -- created by the bonding of an antimicrobial layer to conventional, clear polyethylene plastic typically used to vacuum-package foods such as meat and fish -- could help to decrease foodborne illness outbreaks, according to researchers in Penn State's College of Agricultural Sciences.

21 Jan 2020

Lung microbiome of critically ill patients is predictive of clinical outcomes

Changes in the lung microbiome may help predict how well critically ill patients will respond to care, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

21 Jan 2020

Gut microbiome linked to behavioral problems in children

Children with behavioral problems may have different compositions in their gut microbiome, with parents playing a major role in how pronounced the differences were, other than the food they provide, a new study suggests.

21 Jan 2020

Antiviral compound from banana plants shows potential for clinical use against influenza

What keeps most infectious disease researchers up at night aren't infamous viruses like Ebola. Instead, influenza, commonly known as the flu, continues to be a clear and present danger to humanity.

21 Jan 2020

Study sets the record straight on unproven therapy to treat sepsis

The Jan. 17 issue of the Journal of the American Medical Association features an important study about sepsis with an accompanying editorial by a University of Nebraska Medical Center expert.

17 Jan 2020

New learning module for testing the effects of e-cigarette vapor on living cells

To complement the wide range of information on the potential dangers of vaping, the Cornell University College of Veterinary Medicine has developed a new learning module for high school classrooms that encourages students to directly test the effects of e-cigarette vapor on living cells.

12 Jan 2020

Boston researchers develop novel approach to generate intestinal organoids in vitro

Boston researchers have developed a new way to generate groups of intestinal cells that can be used, among others, to make disease models in the lab to test treatments for diseases affecting the gastrointestinal system.

11 Jan 2020

Researchers discover important role for macropinocytosis in mammalian cell growth

For the first time, researchers at Michigan Medicine have demonstrated that a cellular process known to be involved in cancer and other diseases also plays an important role in the growth of at least one type of normal mammalian cell.

10 Jan 2020

Researchers one step closer to developing vaccines that protect infants against infections

A new Penn Medicine study puts researchers within closer reach of vaccines that can protect infants against infections by overcoming a mother's antibodies, which are known to shut down immune defenses initiated by conventional vaccines.

9 Jan 2020

Study: Environment changes can impact stability landscape of the gut microbial community

Your fingerprints stay the same all your life. But what about the "fingerprint" of microbial strains that are shared in the guts of childhood twins?

9 Jan 2020

Extremely low concentrations of acetic acid could alter cellular processes in rice blast fungus

All living organisms respond and adapt to changes in their environment. These responses are sometimes so significant that they cause alterations in the internal metabolic cycles of the organism--a process called "metabolic switching." For example, rice blast fungus--a pathogenic fungal species that causes the "rice blast" infection in rice crops--switches to the "glyoxylate cycle" when the nutrient source starts to deplete.

8 Jan 2020

Researchers uncover a response key to the survival of Mycoplasma genitalium in urogenital tract

A study led by an IBB-UAB research team has managed to identify the mechanisms by which the sexually transmitted bacterium Mycoplasma genitalium (Mge) can persist in conditions with very limited availability of metals, a circumstance it must face when infecting humans.

8 Jan 2020

Microbiology News and Research

New drug combination destroys bacterial infection that can be fatal to cystic fibrosis patients

New vaccine against African swine fever appears to be more effective than previous vaccines

Researchers identify novel cellular entry factor for AAV vector types

New method reveals how giant viruses infect amoeba

Scientists reverse HIV latency, take major scientific step toward curative therapies

Johns Hopkins researchers warn of new infectious diseases and death due to global warming

Injecting nanoparticles into the bloodstream to reduce brain swelling after traumatic brain injury

Study shows how gene therapy may help protect against vision loss in multiple sclerosis

Novel composite could help to reduce foodborne illness outbreaks

Lung microbiome of critically ill patients is predictive of clinical outcomes

Gut microbiome linked to behavioral problems in children

Antiviral compound from banana plants shows potential for clinical use against influenza

Study sets the record straight on unproven therapy to treat sepsis

New learning module for testing the effects of e-cigarette vapor on living cells

Boston researchers develop novel approach to generate intestinal organoids in vitro

Researchers discover important role for macropinocytosis in mammalian cell growth

Researchers one step closer to developing vaccines that protect infants against infections

Study: Environment changes can impact stability landscape of the gut microbial community

Extremely low concentrations of acetic acid could alter cellular processes in rice blast fungus

Researchers uncover a response key to the survival of Mycoplasma genitalium in urogenital tract

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