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Novel mouse model confirms how “good” and “bad” bacteria affect human acne

Researchers have long believed that Propionibacterium acnes causes acne. But these bacteria are plentiful on everyone's skin and yet not everyone gets acne, or experiences it to the same degree.

8 Mar 2019

Common fungus found on skin may cause inflammatory bowel disease

Therapies that target certain commensal fungi could provide a new way of treating inflammatory bowel disease (IBD), according to researchers.

6 Mar 2019

Aging and high-fat diet disrupt gut microbiome to cause inflammation in heart failure

Growing older and a high-fat diet enriched with omega 6 fatty acids are major contributors to health risks ranging from diabetes to heart failure. How these two factors regulate the immune response is not well-understood.

1 Mar 2019

Research identifies super-enhancers as novel target for pancreatic ductal adenocarcinoma

Differential H3K27AC marks were identified at enhancer regions of genes including c-MYC, MED1, OCT-4, NANOG, and SOX2 that can act as super-enhancers (SE), cluster of genes in non-cancerous, cancerous and metastatic PDAC cell lines.

1 Mar 2019

Scientists find clue to rapid human conversations in singing mice

Studying the songs of mice from the cloud forests of Costa Rica, researchers from New York University School of Medicine and The University of Texas at Austin have identified a brain circuit that might enable the high-speed back and forth of human conversation.

1 Mar 2019

New study explores stem cells to gain insight into rotator cuff disease

Rotator cuff tears are common injuries, and proper healing of the shoulder muscle is often difficult.

27 Feb 2019

New protein 'switch' could stop progression of blood-poisoning and increase chances of survival

Scientists at the University of British Columbia have discovered a new protein "switch" that could stop the progression of blood-poisoning, or sepsis, and increase the chances of surviving the life-threatening disease.

26 Feb 2019

Researchers discover new and rare skeletal disease

Researchers at Karolinska Institutet in Sweden have discovered a new and rare skeletal disease. In a study published in the journal Nature Medicine they describe the molecular mechanism of the disease, in which small RNA molecules play a role that has never before been observed in a congenital human disease.

25 Feb 2019

Researchers discover origin of resistance to lung cancer

For treating cancer, drugs based on molecules known as tyrosine kinase inhibitors are sometimes used. One such tyrosine kinase inhibitor, called osimertinib, has been used to treat EGFR-mutated lung cancer with a certain degree of efficacy.

25 Feb 2019

New study finds how high-fat diets fuel colorectal cancer growth

As cancer death rates drop overall, doctors have noted a frightening anomaly: deaths from colorectal cancer in people under 55 appear to be creeping up. According to the American Cancer Society, deaths in this younger group increased by 1 percent between 2007 and 2016.

22 Feb 2019

Innovative compound offers a new therapeutic approach to treat multiple sclerosis

Multiple sclerosis is an autoimmune disease that affects more than 2.3 million people worldwide. This debilitating condition periodically shutters communication between the brain and other parts of the body, resulting in symptoms that range from numbness and tingling in the arms and legs to blindness and paralysis.

22 Feb 2019

Newly designed molecule could benefit people with Friedrich's Ataxia

Skin cells taken from patients with a rare genetic disorder are up to ten times more sensitive to damage from ultraviolet A radiation in laboratory tests, than those from a healthy population, according to new research from the University of Bath.

21 Feb 2019

Scientists can monitor brain activity to predict epileptic seizures few minutes in advance

Elizabeth Delacruz can't crawl or toddle around like most youngsters nearing their second birthday.

21 Feb 2019

Why melanoma tumors in the brain may be worse?

Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites.

20 Feb 2019

Researchers engineer stem cell with ‘suicide genes’ to induce cell death in all but beta cells

Researchers have been advancing methods to generate insulin-producing beta cells from pluripotent stem cells for the clinical treatment of type 1 diabetes.

20 Feb 2019

New screening method could catch organ rejection much earlier without a biopsy needle

Too often, it's only after a transplanted organ has sustained serious damage that a biopsy reveals the organ is in rejection. A new screening method using sensor particles and a urine test could catch rejection much earlier, more comprehensively, and without a biopsy needle.

20 Feb 2019

New forms of older anti-cancer agent appear to enhance immune response to fight melanoma

Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins and the Johns Hopkins University School of Medicine report two new forms of an older anti-cancer agent they developed appear to enhance the immune system's ability to fight melanoma in mice.

20 Feb 2019

Newly developed gene therapy helps decelerate aging process

Aging is a leading risk factor for a number of debilitating conditions, including heart disease, cancer and Alzheimer's disease, to name a few. This makes the need for anti-aging therapies all the more urgent. Now, Salk Institute researchers have developed a new gene therapy to help decelerate the aging process.

20 Feb 2019

Researchers explain why T cells lose their protective ability in inflamed tissues

Regulatory T cells make sure that immune responses are not too strong and that inflammation is inhibited. This makes them highly interesting for therapies against inflammatory autoimmune diseases such as multiple sclerosis.

20 Feb 2019

Researchers capture altered brain activity patterns of Parkinson's in mice

The tell-tale tremors of Parkinson's disease emerge from abnormal activity in a brain region crucial for voluntary movement.

19 Feb 2019

Mouse Model News and Research

Novel mouse model confirms how “good” and “bad” bacteria affect human acne

Common fungus found on skin may cause inflammatory bowel disease

Aging and high-fat diet disrupt gut microbiome to cause inflammation in heart failure

Research identifies super-enhancers as novel target for pancreatic ductal adenocarcinoma

Scientists find clue to rapid human conversations in singing mice

New study explores stem cells to gain insight into rotator cuff disease

New protein 'switch' could stop progression of blood-poisoning and increase chances of survival

Researchers discover new and rare skeletal disease

Researchers discover origin of resistance to lung cancer

New study finds how high-fat diets fuel colorectal cancer growth

Innovative compound offers a new therapeutic approach to treat multiple sclerosis

Newly designed molecule could benefit people with Friedrich's Ataxia

Scientists can monitor brain activity to predict epileptic seizures few minutes in advance

Why melanoma tumors in the brain may be worse?

Researchers engineer stem cell with ‘suicide genes’ to induce cell death in all but beta cells

New screening method could catch organ rejection much earlier without a biopsy needle

New forms of older anti-cancer agent appear to enhance immune response to fight melanoma

Newly developed gene therapy helps decelerate aging process

Researchers explain why T cells lose their protective ability in inflamed tissues

Researchers capture altered brain activity patterns of Parkinson's in mice

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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