Genes News and Research

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Intelligence is strongly influenced by the quality of the brain's axons

They say a picture tells a thousand stories, but can it also tell how smart you are? Actually, say UCLA researchers, it can.

17 Mar 2009

MicroRNA undermines tumor suppression

Scientists at the Whitehead Institute for Biomedical Research and the National University of Singapore have discovered the first microRNA (miRNA) capable of directly tamping down the activity of the well known tumor-suppressor gene, p53, While p53 functions to prevent tumor formation, the p53 gene is thought to malfunction in more than 50% of cancerous tumors.

17 Mar 2009

MRSA study suggests strategy shift needed to develop effective therapeutics

USA300-the major epidemic strain of methicillin-resistant Staphylococcus aureus (MRSA) causing severe infections in the United States during the past decade-inherits its destructiveness directly from a forefather strain of the bacterium called USA500 rather than randomly acquiring harmful genes from other MRSA strains.

17 Mar 2009

Hearing could hold key to unlocking schizophrenia mystery

Measuring brain waves in response to hearing a variety of tones appears to be a useful way to begin understanding the underlying genetic abnormalities associated with schizophrenia, says a study headed by researchers at Harvard-affiliated McLean Hospital.

17 Mar 2009

Search for blood pressure secrets reveals a surprising new syndrome

Yale researchers investigating the genetic causes of blood pressure variation have identified a previously undescribed syndrome associated with seizures, a lack of coordination, developmental delay and hearing loss.

16 Mar 2009

Scientists 'watch' as individual alpha-synuclein proteins change shape

In an Early Edition publication of The Proceedings of the National Academy of Sciences (PNAS) this week, the researchers demonstrate the "alpha-synuclein dance" - the switching back and forth of the protein between a bent helix and an extended helix as the surface that it is binding to changes.

16 Mar 2009

Cause of severe pediatric epilepsy disorder discovered

Researchers at the University of California, San Diego School of Medicine have discovered that convulsive seizures in a form of severe epilepsy are generated, not on the brain's surface as expected, but from within the memory-forming hippocampus.

16 Mar 2009

Discovery of master switch that might prevent cancer cells from metastasizing

Researchers at the University of Pennsylvania School of Medicine have identified a master switch that might prevent cancer cells from metastasizing from a primary tumor to other organs.

16 Mar 2009

Researchers show how proteins find the right DNA sequences

Researchers at Uppsala University and Harvard University have collaboratively developed a new theoretical model to explain how proteins can rapidly find specific DNA sequences, even though there are many obstacles in the way on the chromosomes.

16 Mar 2009

Houseflies may contribute to the dispersion of drug-resistant bacteria

Researchers at the Johns Hopkins Bloomberg School of Public Health found evidence that houseflies collected near broiler poultry operations may contribute to the dispersion of drug-resistant bacteria and thus increase the potential for human exposure to drug-resistant bacteria.

16 Mar 2009

Immune cells play surprising role in cystic fibrosis lung damage

Immune cells once thought to be innocent bystanders in cystic fibrosis may hold the key to stopping patients' fatal lung disease.

16 Mar 2009

Alzheimer's disease neuroimaging initiative announces completion of genome-wide analysis

Researchers announced today that a high-density genome wide analysis of participants in the Alzheimer's Disease Neuroimaging Initiative (ADNI; www.adni-info.org) is more than 95% complete and that data will be shared with scientists around the world for further analysis.

16 Mar 2009

Study reinforces the importance of healthy living for women

Women who maintain a healthy weight and who have lower perceived stress may be less likely to have chromosome changes associated with aging than obese and stressed women, according to a pilot study that was part of the Sister Study.

16 Mar 2009

Proteomics study shows that genes involved in invertebrate longevity have surprising parallels in humans

Prolexys Pharmaceuticals has announced the publication of the discovery of genes that are likely to have a role in the aging process of humans.

15 Mar 2009

Prion discovery gives clue to control of mass gene expression

The discovery in common brewer's yeast of a new, infectious, misfolded protein -- or prion -- by University of Illinois at Chicago molecular biologists raises new questions about the roles played by these curious molecules, often associated with degenerative brain diseases like "mad cow" and its human counterpart, Creutzfeldt-Jakob.

15 Mar 2009

Malaria immunity trigger found for multiple mosquito species

Researchers at the Johns Hopkins Bloomberg School of Public Health have for the first time identified a molecular pathway that triggers an immune response in multiple mosquito species capable of stopping the development of Plasmodium falciparum -the parasite that causes malaria in humans.

15 Mar 2009