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IRCM researchers show importance of DNA architecture in controlling activity of genes

A study conducted by Marie Kmita's team at the IRCM, in collaboration with Jos-e Dostie at McGill University, shows the importance of the chromatin architecture in controlling the activity of genes, especially those required for proper embryonic development.

17 Jan 2014

Study shows high-fiber diet reduces risk of colon problems

Scientists have more reasons for you to eat fiber and not abuse antibiotics.

17 Jan 2014

Study explores the role of DNA in predisposing individuals to diseases

A group of international researchers, led by a research fellow in the Harvard Medical School-affiliated Institute for Aging Research at Hebrew SeniorLife, published a paper today in Cell describing a study aimed at better understanding how inherited genetic differences, or variants, predispose certain individuals to develop diseases such as type 2 diabetes.

16 Jan 2014

New dye more effective in detecting, measuring cardiolipin in cell membranes

A team that includes Dartmouth College researchers has discovered a new way to detect cardiolipin, a key indicator of heart diseases and some genetic disorders.

16 Jan 2014

Severe infection associated with increased risk for psychotic illness

Hospital admission for infections in childhood is associated with an increased risk for being diagnosed with nonaffective psychosis later in life, research indicates.

16 Jan 2014

FDA-regulated study investigates use of child's stem cells for acquired sensorineural hearing loss

Cord Blood Registry, the world's largest and most experienced newborn stem cell company, announces the start of a U.S. Food and Drug-regulated study being conducted at Florida Hospital for Children in Orlando to investigate the use of a child's stem cells from their own stored umbilical cord blood as a treatment for acquired sensorineural hearing loss.

16 Jan 2014

Transgenomic, Horizon Discovery collaborate to develop improved genetic diagnostic tests with state of art controls

Transgenomic, Inc. (OTCBB: TBIO), a global biotechnology company advancing personalized medicine in cardiology, oncology, and inherited diseases through diagnostic tests as well as clinical and research services, and Horizon Discovery Ltd. (Horizon), a leading provider of research tools to support translational genomics and the development of personalized medicines, today announced they have entered into a collaboration agreement to develop improved genetic diagnostic tests incorporating state of the art controls.

16 Jan 2014

New gene therapy restores some sight in people born with inherited form of blindness

A new gene therapy has restored some sight in people born with an inherited, progressive form of blindness. The technique replaces a defective gene in the eye with a normal working copy of the gene using a single injection.

16 Jan 2014

Scientists develop novel treatment for Hairy Cell Leukaemia using drug administered to combat skin cancer

A team of scientists from the University of Leicester has demonstrated a novel treatment for Hairy Cell Leukaemia (HCL), a rare type of blood cancer, using a drug administered to combat skin cancer.

16 Jan 2014

Study links later school start times to improved sleep and mood in teens

Julie Boergers, Ph.D., a psychologist and sleep expert from the Bradley Hasbro Children's Research Center, recently led a study linking later school start times to improved sleep and mood in teens.

16 Jan 2014

Research shows how coevolution between humans and bacteria can affect gastric cancer risk

Research carried out in two distinct communities in Colombia illustrates how coevolution between humans and bacteria can affect a person's risk of disease. Working with colleagues in Columbia and the U.S., Scott Williams, PhD, a professor of genetics at the Geisel School of Medicine at Dartmouth, and his graduate student Nuri Kodaman discovered that the risk of developing gastric cancer depends heavily on both the ancestry of the person and the ancestry of Helicobacter pylori with which that person is infected.

15 Jan 2014

New study examines factors that may lead to end stage renal disease

About 33 percent of people with type 2 diabetes suffer kidney damage that progresses to end stage renal disease, at which point they require either dialysis or kidney transplantation. Scientists have thought that this kidney disease is driven by damage to the glomeruli, blood vessels in the kidney, which spill the protein albumin into the urine. Current treatments targeting the resulting "albuminuria" do not prevent kidney failure.

15 Jan 2014

International study develops refined method to identify individuals at risk for certain inherited cancer

An international study has developed a refined method to identify people at risk for certain inherited cancer as a result of Lynch syndrome.

15 Jan 2014

Presence of gene variant in people with MCI associated with accelerated rates of brain atrophy

The presence of a gene variant in people with mild cognitive impairment is associated with accelerated rates of brain atrophy, according to a new study published online in the journal Radiology.

15 Jan 2014

Individuals with multiple sclerosis may have increased risk of developing cancer

Individuals with multiple sclerosis may have an increased risk of developing any type of cancer, with an especially high risk of developing breast cancer. That is the conclusion of a recent study published in European Journal of Neurology. Because the findings contradict earlier studies, additional research is needed to determine whether a true link exists between multiple sclerosis and cancer.

15 Jan 2014

Cortical thickness changes may contribute to early schizophrenia

Altered cortical thickness is related to the severity of positive symptoms in patients with first-episode schizophrenia, but not to the duration of untreated illness, report researchers.

14 Jan 2014

Finland researchers identify mechanism that enhances prostate cancer proliferation, metastasis

A research group at Biocenter Oulu in Finland has identified a mechanism related to a transcription factor that binds much more strongly onto a particular SNP variant, thereby initiating a genetic programme which enhances prostate cancer proliferation and metastasis.

13 Jan 2014

Researchers discover two genetic mutations associated with Familial Alzheimer's Disease

New research, led by Rensselaer Polytechnic Institute researcher Chunyu Wang, has solved one mystery in the development of Familial Alzheimer's Disease (FAD), a genetic variant of the disease that affects a small fraction of the Alzheimer's population. In a paper published online January 6 in the journal Nature Communications, Wang and his team follow the trail of two genetic mutations - V44M and V44A - known to cause FAD, and show how the mutations lead to biochemical changes long linked to the disease.

13 Jan 2014

Smoking and cancer: an interview with Dr. Lewis Foxhall, VP of Health Policy, University of Texas MD Anderson Cancer Center

The report Smoking and Health: Report of the Advisory Committee to the Surgeon General, identified tobacco as the predominant cause of lung cancer in men. This was the first widely disseminated report based on scientific studies showing the clear link between smoking tobacco and serious health conditions including cancer, chronic lung diseases and heart disease.

13 Jan 2014

Study: Variations in non-coding sections of genome might be main contributors to type 2 diabetes risk

Variations in non-coding sections of the genome might be important contributors to type 2 diabetes risk, according to a new study.

13 Jan 2014

Genetic News and Research

IRCM researchers show importance of DNA architecture in controlling activity of genes

Study shows high-fiber diet reduces risk of colon problems

Study explores the role of DNA in predisposing individuals to diseases

New dye more effective in detecting, measuring cardiolipin in cell membranes

Severe infection associated with increased risk for psychotic illness

FDA-regulated study investigates use of child's stem cells for acquired sensorineural hearing loss

Transgenomic, Horizon Discovery collaborate to develop improved genetic diagnostic tests with state of art controls

New gene therapy restores some sight in people born with inherited form of blindness

Scientists develop novel treatment for Hairy Cell Leukaemia using drug administered to combat skin cancer

Study links later school start times to improved sleep and mood in teens

Research shows how coevolution between humans and bacteria can affect gastric cancer risk

New study examines factors that may lead to end stage renal disease

International study develops refined method to identify individuals at risk for certain inherited cancer

Presence of gene variant in people with MCI associated with accelerated rates of brain atrophy

Individuals with multiple sclerosis may have increased risk of developing cancer

Cortical thickness changes may contribute to early schizophrenia

Finland researchers identify mechanism that enhances prostate cancer proliferation, metastasis

Researchers discover two genetic mutations associated with Familial Alzheimer's Disease

Smoking and cancer: an interview with Dr. Lewis Foxhall, VP of Health Policy, University of Texas MD Anderson Cancer Center

Study: Variations in non-coding sections of genome might be main contributors to type 2 diabetes risk

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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