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Study predicts that different statins exhibit divergent effects on host response to SARS-CoV-2 infection

A new study explores the possibility that different statins may exhibit different effects within the host and may differ in their outcomes while treating COVID-19 patients.

18 Apr 2022

Research shows effectiveness of a 3rd mRNA COVID-19 vaccine dose

A recent study assessed the efficacy of the second and third doses of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) messenger ribonucleic acid (mRNA) vaccines against the SARS-CoV-2 Omicron and Delta variants in outpatient settings.

13 Apr 2022

Newcastle disease virus-based trivalent vaccine found to be effective across SARS-CoV-2 variants in mice

In a new study, researchers tested the bi-, tri-, and tetravalent formulations of Newcastle disease virus (NDV)-based low-cost vaccine in mice.

29 Mar 2022

How capable are children to self-swab for SARS-CoV-2?

Researchers gather data that supports the evidence-based recommendations for children to successfully perform nasal swabs on themselves.

15 Mar 2022

New Phase 1 clinical trial of mRNA HIV vaccine enrolls first participant

The first 12 study participants have been enrolled in a new Phase 1 clinical trial using the messenger ribonucleic acid (mRNA) vaccine technology developed by Moderna.

14 Mar 2022

Tumor cells’ 'ferroaddiction' can be exploited to deliver powerful anticancer drugs

Researchers at the University of California, San Francisco, have discovered that cells carrying the most common mutation found in human cancer accumulate large amounts of ferrous iron and that this "ferroaddiction" can be exploited to specifically deliver powerful anticancer drugs without harming normal, healthy cells.

11 Mar 2022

Genomic surveillance of bacterial colonies could help physicians keep closer tabs on drug resistance

Antibiotic-resistant bacterial infections are difficult to treat and cause more than a million annual deaths worldwide, especially in hospitalized patients with pneumonia, bloodstream infections, urinary tract infections, or abdominal infections.

11 Mar 2022

Study shows anti-itch and pain relief potential of protein in tick saliva

A protein found in tick saliva could be turned into a drug that eases itching and chronic pain in people.

8 Mar 2022

Development of RT-qPCR assays for differentiating SARS-CoV-2 Omicron BA.1 and BA.2 variants

In a recent study posted to the medRxiv*preprint server, a team of researchers from Israel developed and validated novel reverse transcriptase - quantitative polymerase chain reaction (RT-qPCR) assays. The new assays enable the rapid and high throughput identification and differentiation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1 and BA.2 variants.

8 Mar 2022

World Trade Center responders have increased levels of mutations that escalate blood cancer risk

Scientists from Vanderbilt-Ingram Cancer Center (VICC) collaborated with researchers from New York to determine that 9/11 first responders to the World Trade Center have increased levels of mutations that escalate their risk for blood cancers or cardiovascular disease, according to a study published March 7 in Nature Medicine.

7 Mar 2022

SARS-CoV-2 monitoring could be improved with use of bacterial metatranscriptomes in wastewater

In a recent research report from the United States, currently available on bioRxiv* preprint server, scientists have shown that bacterial taxonomic and functional profiles can discriminate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) status even without directly detecting viral transcripts – opening the door for entirely novel approaches in wastewater-based epidemiology.

27 Feb 2022

Monitoring rise of SARS-CoV-2 variants in wastewater using genome sequencing

Researchers conduct genomic wastewater surveillance of SARS-CoV-2 following the emergence of the Alpha and Delta variants in the United Kingdom.

21 Feb 2022

SARS-CoV-2 human challenge study offers novel insights into viral kinetics

Researchers discuss the results of a human challenge study to provide novel insights into the early dynamics of SARS-CoV-2 infection.

3 Feb 2022

Researchers develop a single-use sensor strip to detect cerebrospinal fluid leaks

Developing rapid clinical testing for cerebrospinal fluid (CSF) leaks after trauma, surgery, tumors, and other defects are vital, because such leaks can cause life-threatening conditions, such as meningitis and intercranial infection.

1 Feb 2022

Nucleocapsid antigen found to be a sensitive biomarker for acute COVID-19 infection

In a new study, researchers found that nucleocapsid antigen in the blood (antigenemia) is a sensitive and specific biomarker for acute coronavirus disease 2019 infection.

31 Jan 2022

Urinary proteomic COV50 marker accurately predicts adverse COVID-19 outcomes

The researchers described COV50, a urinary biomarker, that can predict death and disease progression in COVID-19.

26 Jan 2022

Novel experimental drug designed to silence FUS gene may help treat ALS

Using an experimental drug, researchers were able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene.

24 Jan 2022

Asymptomatic COVID-19 patients less infectious than symptomatic patients

Researchers investigate the progression of infection in students and employees who tested positive for SARS-CoV-2 at Boston University.

16 Jan 2022

New insights into reforming the actions that hindered Seattle researchers from community testing for COVID-19

As the two-year anniversary of the pandemic approaches, a new commentary provides insights into reforming the "labyrinth of conflicting and uncoordinated actions among state and federal regulators" that in early 2020 hampered Seattle researchers from community testing for COVID-19.

11 Jan 2022

Humoral and cellular response to primary and booster COVID-19 vaccination in immunosuppressed patients

Researchers posted the results of a retrospective observational cohort study in which they determined the humoral and cellular responses in ISP to primary and booster doses of COVID-19 vaccines.

10 Jan 2022