Creutzfeldt Jakob Disease News and Research

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Creutzfeldt–Jakob disease or CJD (sometimes incorrectly referred to as mad cow disease) is a degenerative neurological disorder (brain disease) that is incurable and invariably fatal. It is the most common among the types of transmissible spongiform encephalopathy found in humans.

First confirmed case of Mad Cow disease in Holland

The first known case of the human form of "mad cow disease" - known as variant Creutzfeldt-Jakob Disease (vCJD), has been diagnosed in the Netherlands.

22 Apr 2005

Researchers and drug giant team up to find cure for CJD

The Medical Research Council's Prion Unit, based at University College London, a leading British research group, is joining forces with drugs giant GlaxoSmithKline (GSK) to develop a cure for the disease Creutzfeldt-Jakob Disease (CJD).

12 Apr 2005

New system for growing human embryonic stem cells could make therapies utilising the cells safer for patients

A new system for growing human embryonic stem cells could make therapies utilising the cells safer for patients, concludes a study published online by The Lancet (Tuesday, March 8, 2005).

8 Mar 2005

Research into how prions act in the brain could hold the key to defeating diseases

Scientists at the University of Southampton are continuing their pioneering research into diseases such as Creutzfeld-Jakob Disease (CJD) and related conditions caused by tiny particles known as prions, thanks to a £300,000 grant from the Medical Research Council.

1 Mar 2005

Diagnosis of prions in patients should utilize novel strategy, conformation-dependent immunoassay

A technique for detecting prions in tissue, developed in recent years by UCSF scientists, is significantly more sensitive than the diagnostic procedures currently used to detect the lethal particles in samples of brain tissue from patients, according to a study performed by a UCSF team.

22 Feb 2005

New clues to amyloidoses

Familial amyloid polyneuropathy (FAP), a hereditary disease characterised by abnormal deposits of insoluble protein in the organs, results from a mutation in a single gene (the transthyretin or TTR gene). Nevertheless, disease incidence and age of onset can vary significantly between patients what have always puzzled scientists.

21 Feb 2005

Ireland is reporting its first case of variant Creutzfeldt-Jakob disease

The man in his early 20's was admitted to hospital as a suspected case 4 weeks ago. Recent tests on the patient's tonsils have detected the presence of the protein which causes vCJD.

11 Nov 2004

Mad cow disease prions can be removed from blood

New research results released today confirm that infectious variant Creutzfeldt-Jakob Disease (vCJD) prions that cause the human form of "mad cow disease" can be removed from blood.

From Pall Corporation 3 Nov 2004

Large-scale screening programme of tonsil tissue is the only way of identifying the true incidence of vCJD infection

A study in this week’s issue of THE LANCET describes how two different types of analysis used in conjunction on samples of tonsil tissue is the ‘gold standard’ method for confirming clinical variant CJD

30 Sep 2004

New capsule, made from fish gelatin, should end fears of viral infections such as BSE and vCJD

An alternative to mammalian gelatin for use in pharmaceutical soft capsules has been discovered by researchers at the School of Pharmacy and Chemistry at Liverpool John Moores University.

28 Sep 2004

Steps to minimise the risk of onward transmission of vCJD

Selected groups of patients are this week being notified about the results of a risk assessment exercise for blood plasma products.

22 Sep 2004

Global health is recurrently being threatened by new and re-emerging infectious diseases

Global health is recurrently being threatened by new and re-emerging infectious diseases. Examples of new and re-emerging infectious diseases include SARS (Severe Acute Respiratory Syndrome), new variant CJD (Creutzfeldt-Jakob Disease), avian flu and Ebola.

20 Sep 2004

Protein that causes juvenile Batten disease also plays a key role in normal cell function

The aberrant protein that causes juvenile Batten disease, a fatal neurodegenerative disorder of childhood, also plays a key role in normal cell function, Duke University Medical Center researchers have found.

16 Sep 2004

One of Australia's largest hospitals has suspected case of Creutzfeldt-Jakob Disease

The Royal Melbourne Hospital, one of Australia's largest hospitals, has contacted 1056 patients today after a man died of a suspected case of Creutzfeldt-Jakob Disease.

13 Sep 2004

John Reid has announced further developments concerning variant Creutzfeldt-Jakob disease

He told MPs in a written ministerial statement that an exercise has begun to notify some recipients of blood products about the results of a risk assessment exercise carried out by the Health Protection Agency.

10 Sep 2004

Chiron acquires a variant Creutzfeldt-Jakob disease research company

Chiron Corporation has announced that it had acquired Prion Solutions Inc., a privately held company based in La Jolla, Calif., focused on research into variant Creutzfeldt-Jakob disease (vCJD) and other prion-related diseases. Financial terms of the acquisition were not disclosed.

1 Sep 2004

Dynamics between disposable and reusable segments affect expansion of disposable drapes and gowns markets

The market for disposable surgical drapes and gowns in Europe has seen steady growth in the recent past owing to the high standards of infection control enforced by the new European Union Medical Device Directive (MDD) and EU regulations.

11 Aug 2004

Second case of variant Creutzfeldt-Jakob disease infection that was probably caused by blood transfusion

Research reported in The Lancet this week details the second case of variant Creutzfeldt-Jakob disease (vCJD) infection that was probably caused by blood transfusion. The rogue prion responsible for vCJD was identified at postmortem five years after an elderly person received a blood transfusion from a donor who later developed vCJD.

5 Aug 2004

Scientists have produced a prion protein that can trigger the development of a neurological disorder similar to "mad cow" disease

Scientists have produced a prion protein that can trigger the development of a neurological disorder in mice that is similar to "mad cow" disease, according to a new study supported by the National Institute on Aging, a part of the National Institutes of Health.

2 Aug 2004

New ethics committee regulations impede and delay clinical research

New ethics committee regulations impede and delay clinical research, sometimes to the extent that conclusions are flawed and patients damaged, according to several articles in this week's BMJ.

29 Jul 2004