Depressive Disorder News and Research

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Penn Medicine launches a new community mental health hub at Hospital of the University of Pennsylvania

Penn Medicine is launching a new community mental health hub at the Hospital of the University of Pennsylvania - Cedar Avenue (HUP Cedar), co-locating inpatient and outpatient psychiatric care with a new crisis response center (CRC) at the facility.

19 May 2023

Policy overhaul needed: Food industry's impact on global brain health

The dominance of the corporate-industrial food industry undermines brain capital and sustainable human development on a global scale. Understanding this impact is crucial for the future of public health and well-being.

17 May 2023

Study shows the power of gamma enhancement as potential approach for countering depression

Led by researchers from NYU Grossman School of Medicine and Hungary's University of Szeged, a new study in mice and rats found that restoring certain signals in a brain region that processes smells countered depression.

9 May 2023

Does physical activity impact substance use disorder treatment?

Researchers reviewed existing studies on physical activity interventions for treating substance use disorders.

28 Apr 2023

Genetic discovery may pave the way for precision medicine approaches to treat depression

A team of scientists at the Medical University of South Carolina (MUSC) has identified a stress-regulated gene that plays a role in the link between long-term stress and a common type of depressive behavior in mice.

7 Apr 2023

The intercommunication between the central nervous system and the digestive system and its contribution to mental health status

Researchers presented a comprehensive analysis of the correlation between gut microbiota and neurological as well as psychiatric disorders.

3 Apr 2023

Early life adversity linked to accelerated neurobiological aging, raising vulnerability to depression and Alzheimer's

scientists investigate the neurocognitive correlates of genetic vulnerability to major depressive disorder and Alzheimer's disease.

30 Mar 2023

Illness severity and clinical instability linked to risk of psychiatric hospitalization

For patients with psychiatric conditions, illness severity and instability are key factors in predicting future risk of hospitalization, according to a new study by Holmusk, a leading behavioral health real-world evidence and data analytics company, that has been published in The Lancet Psychiatry.

28 Mar 2023

Study highlights the role of intestinal T cells in modifying psychological stress responses

In experiments with mice and humans, a team led by Johns Hopkins Medicine researchers says it has identified a particular intestinal immune cell that impacts the gut microbiome, which in turn may affect brain functions linked to stress-induced disorders such as depression.

21 Mar 2023

Gut microbiomes and mental health: how do they interact?

A new study published in the journal Frontiers in Medicine reviewed recent literature on the link between gut microbiota, the brain, and neurological disorders.

19 Mar 2023

Using probiotics to treat depression

Researchers discuss whether probiotics could be used as supplementary or primary therapy to manage major depressive disorder.

15 Mar 2023

Personal use of psychedelics among therapists may be common, study finds

Whether personal use of psychedelics is appropriate among psychedelic therapists, a new study finds that it may be common.

27 Feb 2023

Brain cells may age faster in people with cocaine use disorder

A new study finds evidence from the DNA methylome that the biological age – different from the chronological age – of cells in Brodmann Area 9 of the prefrontal cortex might be greater in people with cocaine use disorder.

16 Feb 2023

Cocaine use disorder leads to changes in the 'methylome' of a brain region

Scientists tend to view substance addiction as primarily a disease of the brain. When we enjoy sex, food, music, or hobbies, regions of our brain within the reward pathway are flooded with pleasure-inducing dopamine.

14 Feb 2023

Young adults with depression and poor mental health more likely to develop cardiovascular disease

Young adults who feel down or depressed are more likely to develop cardiovascular disease (CVD) and have poor heart health, according to a new study led by Johns Hopkins Medicine researchers who analyzed data from more than a half million people between the ages of 18 and 49.

30 Jan 2023

Study finds high prevalence of depression and anxiety in children and adolescents during COVID-19 pandemic

Recently, scientists sought to address this shortcoming and reviewed the existing literature to understand the indirect impact, on mental health, of strategies that were applied to restrict the spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection among children and adolescents.

23 Jan 2023

Did people use mental health services more during the COVID-19 pandemic?

Researchers explored the utilization rates of mental health services among adults during the coronavirus disease 2019 (COVID-19) pandemic.

11 Jan 2023

Scientists gain new insights into the opposing actions of serotonin-producing nerve fibers in mice

New insights into the opposing actions of serotonin-producing nerve fibers in mice could lead to drugs for treating addictions and major depression.

28 Dec 2022

Common psychiatric medications can give some protection against COVID-19

A new meta-analysis shows that psychiatric medications can give some protection against COVID-19, with the common antidepressant fluvoxamine showing the strongest effect.

16 Dec 2022

Health care providers may miss depression symptoms in Black women, study finds

Black women with symptoms of depression more often report sleep disturbances, self-criticism, and irritability than stereotypical symptoms such as depressed mood, according to a new study led by researchers at NYU Rory Meyers College of Nursing and Columbia University School of Nursing.

13 Dec 2022