Ductal Carcinoma News and Research

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Cells lining milk ducts hold key to spread of ductal carcinoma in situ

When a form of cancer that begins in the milk ducts of the breast invades neighboring tissue to spread to other parts of the body, the cause lies not in the tumor cells themselves but in a group of abnormal surrounding cells that cause the walls of the duct to deteriorate like a rusty pipe, according to a new study led by Dana-Farber Cancer Institute researchers.

5 May 2008

Screening mammography in elderly patients beneficial

Although guidelines keep changing regarding screening mammography in elderly patients, those older than 70 years old continue to benefit from this exam, showing that with frequent mammograms breast cancers can be found sooner, according to a recent study conducted by researchers at Jacobi Medical Center and Albert Einstein College of Medicine, in Bronx, NY.

11 Apr 2008

MRI's high false positive rate has little impact on women's choice of preventive mastectomy

Magnetic resonance imaging (MRI) falsely detects breast cancer in five out of every six positive scans according to new research into the use of MRI for women with a high, inherited risk of developing the disease.

26 Mar 2008

COX-2 expression is marker for cancer development in some benign breast biopsies

It's a good news, bad news situation. Some women who have a breast biopsy are told that while they don't have cancer, they do have atypical hyperplasia -- cells that aren't quite normal and might become cancerous someday.

12 Mar 2008

Ductal carcinoma in situ patients overestimate breast cancer risks

Many women diagnosed with ductal carcinoma in situ (DCIS) have inaccurate perceptions of their breast cancer risks, according to a study published online February 12 in the Journal of the National Cancer Institute.

13 Feb 2008

American women prefer overly aggressive treatments for breast cancer

Despite a 1990 consensus recommendation from the National Institutes of Health (NIH) that lumpectomy plus radiation was the treatment of choice for early stage breast cancer, the United States continues to have the highest rate of mastectomy surgery among industrialized countries.

9 Jan 2008

Breast cancer cells have to learn to walk before they can run

Early-stage breast cancer that has not yet invaded the surrounding tissues may already contain highly motile cells, bringing the tumor one step closer to metastasis, report researchers at the Salk Institute for Biological Studies.

2 Jan 2008

Early results show promise in reducing side effects from anastrozole

A common osteoporosis drug can shield women against the loss of bone mineral density - a side effect of the drug anastrozole which is taken to prevent breast cancer in the IBIS-2 study - according to new data presented at the San Antonio Breast Cancer Symposium.

14 Dec 2007

Cell response to stress signals predicts tumors in women with common pre-breast cancer

A specific biological response to cellular stress may predict the likelihood of future tumor formation of the most common, non-invasive form of pre-malignant breast cancer-- ductal carcinoma in situ, or DCIS.

13 Nov 2007

Molecular markers predict risk for invasive breast cancer years before the tumor develops

A team of scientists from the University of California San Francisco has identified distinct molecular markers that predict whether or not a woman is likely to develop subsequent invasive cancer after initial diagnosis with a noninvasive form of early breast cancer.

13 Nov 2007

MRI could help prevent breast cancer progression

Using magnetic resonance imaging (MRI) to diagnose breast cancer in its intraductal stage could help prevent the development of invasive cancer, conclude authors of an Article in The Lancet.

13 Aug 2007

Almac Diagnostics announces major study analysing ductal carcinoma in situ tissue samples

Today Almac Diagnostics announced a major study analysing ductal carcinoma in situ tissue samples using its novel Breast Cancer DSA microarray.

9 Aug 2007

Discovery of method to identify how cancer evades the immune system

One of the fundamental traits of a tumor - how it avoids the immune system - might become its greatest vulnerability, according to researchers from the University of Southern California. Their findings, demonstrated in human breast and colorectal cancers, indicate that a technique for determining a tumor's "immune signature," could be useful for diagnosing and treating specific cancers.

3 Jul 2007

New, potentially more accurate method for diagnosing breast cancer

By combining two techniques, magnetic resonance imaging (MRI) and near-infrared optics, researchers at Dartmouth College and Dartmouth Medical School may have devised a new, potentially more accurate method for diagnosing breast cancer.

14 Apr 2007

DNA methylation and breast cancer

A new study using mastectomy tissue shows that precancerous changes can occur in normal-appearing areas of the breast as distant as two inches from a tumor's edge.

10 Jan 2007

Computer-aided detection essential in preventing breast cancer

Computer-aided detection improves breast cancers in both screening and diagnostic patients according to a recent study done by a private practice radiologist in Santa Barbara, CA.

2 Aug 2006

Breast removal not the only treatment option for non-invasive breast cancer

Breast conserving surgery, long known to be successful at treating the more common invasive cancer, can also be effective for this pre-invasive condition, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center.

8 May 2006

Breast conserving surgery is a good option for early breast cancer

For women diagnosed with a type of non-invasive breast cancer, removing the breast is not the only treatment option.

8 May 2006

Selecting patients for breast conserving therapy: The importance of lobular histology

Invasive lobular carcinoma (ILC) of the breast can be treated with breast conserving surgery (BCT), as is invasive ductal carcinoma (IDC), without greater future risk of radical surgical treatment or additional surgeries, according to a new study.

8 May 2006

Osteoporosis drug Raloxifene shown to be as effective as Tamoxifen in preventing invasive breast cancer

Initial results of the Study of Tamoxifen and Raloxifene, or STAR, show that the drug raloxifene, currently used to prevent and treat osteoporosis in postmenopausal women, works as well as tamoxifen in reducing breast cancer risk for postmenopausal women at increased risk of the disease.

18 Apr 2006

Ductal Carcinoma News and Research

Cells lining milk ducts hold key to spread of ductal carcinoma in situ

Screening mammography in elderly patients beneficial

MRI's high false positive rate has little impact on women's choice of preventive mastectomy

COX-2 expression is marker for cancer development in some benign breast biopsies

Ductal carcinoma in situ patients overestimate breast cancer risks

American women prefer overly aggressive treatments for breast cancer

Breast cancer cells have to learn to walk before they can run

Early results show promise in reducing side effects from anastrozole

Cell response to stress signals predicts tumors in women with common pre-breast cancer

Molecular markers predict risk for invasive breast cancer years before the tumor develops

MRI could help prevent breast cancer progression

Almac Diagnostics announces major study analysing ductal carcinoma in situ tissue samples

Discovery of method to identify how cancer evades the immune system

New, potentially more accurate method for diagnosing breast cancer

DNA methylation and breast cancer

Computer-aided detection essential in preventing breast cancer

Breast removal not the only treatment option for non-invasive breast cancer

Breast conserving surgery is a good option for early breast cancer

Selecting patients for breast conserving therapy: The importance of lobular histology

Osteoporosis drug Raloxifene shown to be as effective as Tamoxifen in preventing invasive breast cancer

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