Gene Sequencing News and Research

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Computational software that evaluates DNA samples may help in diagnosis, treatment of cancer

A research team from the United States and Canada has developed and successfully tested new computational software that determines whether a human DNA sample includes an epigenetic add-on linked to cancer and other adverse health conditions.

From Oxford Nanopore Technologies 24 Feb 2017

Study provides new insight into causes of rare metabolic disorder

Just before Rare Disease Day 2017, a study from the Monell Center and collaborating institutions provides new insight into the causes of trimethylaminura, a genetically-transmitted metabolic disorder that leads to accumulation of a chemical that smells like rotting fish.

14 Feb 2017

Researchers discover function of olfactory receptors in human heart muscle

Researchers have for the first time identified the function of olfactory receptors in the human heart muscle, such as are also present in the nose. One of the receptors reacts to fatty acids that occur in the blood, in patients with diabetes significantly above the normal range.

8 Feb 2017

Scientists decipher emergence of neuronal diversity in the cerebral cortex

The development of cerebral cortex plays a major role in the evolution of species and in particular for mankind.

30 Jan 2017

Researchers map genetic changes resulting from short bowel syndrome

Investigators at Children's Hospital Los Angeles, led by Tracy C. Grikscheit, MD, have mapped the genetic changes resulting from short bowel syndrome using a novel zebrafish model and by performing intensive gene sequencing.

25 Jan 2017

IBBL becomes first biobank to be accredited for next-generation microbial sequencing

Further to a successful follow-up audit, IBBL (Integrated BioBank of Luxembourg) becomes the first biobank worldwide to be accredited for the next-generation 16S rRNA gene sequencing, a cutting-edge method that takes forward research into the human microbiome.

23 Dec 2016

Wellcome Trust Sanger Institute open new biodata innovation centre and sequencing facility

The UK Prime Minister Rt Hon Theresa May today joined key stakeholders from across the life sciences sector to open the Wellcome Trust Sanger Institute’s new Bridget Ogilvie Building and the Biodata Innovation Centre at the Wellcome Genome Campus in Cambridge.

22 Nov 2016

Titin gene mutations affect heart function in healthy individuals, study finds

A multinational study by researchers from the UK, Singapore and Germany has discovered that gene mutations in a protein called titin affect heart function in healthy individuals.

22 Nov 2016

HC-based NGS helps detect genomic alterations not identified in routine lung cancer screening

The use of hybrid capture-based (HC-based) next-generation sequencing (NGS) to identify targetable oncogenic drivers in patients with lung adenocarcinoma results in the detection of genomic alterations (GAs) not identified in routine screening, and impacts treatment decisions and clinical outcomes.

17 Nov 2016

Scientists use latest sequencing technology to review genetic makeup of ataxias syndrome

According to a recent study published in JAMA Neurology, Northwestern Medicine scientists have examined more than a century of data of the genetic makeup of ataxias, a neurodegenerative disorder, to better understand the different forms of this devastating disease and how it affects patients.

8 Nov 2016

Mouths of migraine sufferers harbor more nitrate-reducing bacteria, study finds

Researchers at University of California San Diego School of Medicine have found that the mouths of migraine sufferers harbor significantly more microbes with the ability to modify nitrates than people who do not get migraine headaches.

19 Oct 2016

Novel DNA-altering method could lead to more treatment options for diseases

Researchers in Singapore have developed a new protein that can alter DNA in living cells with much higher precision than current methods.

13 Sep 2016

Study sheds new light on why colon cancers are more aggressive in African Americans

Case Comprehensive Cancer Center researchers, a research collaboration which includes University Hospitals Seidman Cancer Center and Case Western Reserve University, who last year identified new gene mutations unique to colon cancers in African Americans, have found that tumors with these mutations are highly aggressive and more likely to recur and metastasize.

1 Sep 2016

Rare genetic variations linked to severe porphyria

An international research team has linked rare variations in a cell membrane protein to the wide variation in symptom severity that is a hallmark of porphyria, a rare disorder that often affects the skin, liver and nervous system.

10 Aug 2016

Genetic profiling offers new avenues for treatment of cancer, study finds

Genetic profiling of cancer tumors provides new avenues for treatment of the disease, according to a study conducted by Sanford Health and recognized by the American Society of Clinical Oncology.

27 Jul 2016

MS patients have different patterns of gut microorganisms than healthy counterparts

A connection between the bacteria living in the gut and immunological disorders such as multiple sclerosis have long been suspected, but for the first time, researchers have detected clear evidence of changes that tie the two together.

12 Jul 2016

CDC invests in Donator’s unique heat stabilization technology

Denator, the Swedish-based biotechnology company specialized in biological sample preparation technologies announced today that the Center for Disease Control and Prevention, Atlanta, had made a major purchase of its proprietary heat stabilization technology Stabilizor T1™.

6 Jul 2016

Scientists develop computational method to map cancer progression

A team of scientists has developed a computational method to map cancer progression, an advance that offers new insights into the factors that spur this affliction as well as new ways of selecting effective therapies.

28 Jun 2016

Absence of one specific species of gut bacteria causes autism-related social deficits in mice

The absence of one specific species of gut bacteria causes social deficits in mice, researchers at Baylor College of Medicine report June 16 in Cell. By adding this bacterial species back to the guts of affected mice, the researchers were able to reverse some of the mice's behavioral deficits, which are reminiscent of symptoms of autism spectrum disorders (ASDs) in humans.

17 Jun 2016

Researchers reveal how cancer cells use energy to move and divide so quickly

Cancer cells and normal cells both divide and move, but with cancer cells it's like they're on steroids: everything is bigger, faster, more.

15 Jun 2016