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Understanding how neutrophil signaling pathways disrupt the human intestinal barrier

The intestinal mucosal barrier separates the host from the gut lumen and is essential for systemic homeostasis.

14 Oct 2026

Novel gene rejuvenation therapy preserves cell identity while reversing age

Every organ and tissue progressively loses function and integrity as it ages. In fact, researchers have identified "hallmarks of aging" that not only present specific processes impacted by age, but are also thought of as levers that, if successfully targeted, could help turn back the aging clock and result in tissue rejuvenation.

14 Oct 2026

Early vasopressin use does not improve septic shock survival

A new study from researchers at Intermountain Health in Salt Lake City found that starting an advanced medication earlier for critically ill patients with life-threatening septic shock does not improve their survival, shorten hospital stays, or improve their recovery compared with waiting until their condition potentially worsens.

14 Oct 2026

Common asthma drug improves strength in children with muscle disease

A common asthma medication improves motor skills and muscle strength in children with congenital myopathies, a group of incurable muscle diseases.

14 Oct 2026

Scientists identify novel autoimmune driver behind DNA repair breakdown in childhood cancer

Researchers have found the first evidence for a previously unsuspected cause of pediatric cancer. They showed that children with such cancers were more likely than their healthy peers to produce ‘auto-antibodies’ targeting six proteins necessary for normal DNA repair. Likewise, they showed that young adults with cancer had greater amounts of these circulating antibodies already years before diagnosis.

14 Oct 2026

Researchers uncover how metastatic colorectal cancer evades immune attack

Researchers at Hokkaido University, in collaboration with an international team of scientists led by the University of South Florida Health and Tampa General Hospital, have uncovered an important mechanism behind immune evasion in metastatic colorectal cancer (mCRC).

13 Oct 2026

Improving nurse staffing could ease emergency department crowding

A new study led by researchers from Penn Nursing's Center for Health Outcomes and Policy Research (CHOPR) finds that improving hospital nurse workloads could alleviate delays in care contributing to emergency department crowding.

13 Oct 2026

CHOP researchers link MAP2K4 variants to a neurodevelopmental disorder

Researchers from Children's Hospital of Philadelphia (CHOP) have discovered the mechanisms of previously unknown changes in a gene that result in symptoms associated with a neurodevelopmental disorder.

13 Oct 2026

Enhanced CAR T-cell therapy may improve treatment options for patients with B-cell blood cancers

Results from a phase I clinical trial led by The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) show a possible way to improve therapy options for patients with relapsed or treatment-resistant B-cell blood cancers.

13 Oct 2026

Maternal opioid use in pregnancy linked to childhood hospitalizations

Children whose mothers received opioid prescriptions during pregnancy have a higher rate of hospital admission in childhood than unexposed children, including unexposed siblings, according to a new study published October 13th in the open access journal PLOS Medicine by Dong Keon Yon of Kyung Hee University College of Medicine, South Korea, and colleagues.

13 Oct 2026

Charity funds Aston University research into childhood cancer MRI

Aston University's Dr Jan Novak has accepted funding of £45,000 from cancer charity Help Harry Help Others (HHHO) to support a PhD student to research new ways of using MRI scans of children with cancer to better inform their doctors and improve treatment.

13 Oct 2026

Topical peptide spray outperforms placebo in healing burn wounds

Burn wound infections remain a major global health burden, often requiring hospitalization and delaying tissue repair.

13 Oct 2026

New AI tool distinguishes Ewing sarcoma with high accuracy

A team from the Universitat Politècnica de València (UPV) and the University of Valencia (UV) has developed and validated an artificial intelligence (AI) system capable of distinguishing Ewing sarcoma from other morphologically similar tumours with high accuracy.

13 Oct 2026

Major trial seeks to test semaglutide on adults with alcohol and opioid use disorder

The Center for Addiction Science, Policy and Research (CASPR) and the Allegheny County Department of Human Services are preparing to launch a major $13.3 million randomized controlled trial to test whether weekly semaglutide, as an additional support to existing care, can reduce alcohol and opioid use and reduce criminal-justice involvement while improving employment, health, and housing outcomes among people at elevated risk of criminal-justice involvement.

13 Oct 2026

Childhood leukemia treatment causes rapid, lasting challenges for patient families

New research in the October 2026 issue of JNCCN-Journal of the National Comprehensive Cancer Network finds that families of children receiving treatment for B-cell acute lymphoblastic leukemia (B-ALL) experience substantial and lasting challenges beginning early after diagnosis, according to a new multicenter study embedded in a Children's Oncology Group (COG) trial.

13 Oct 2026

Targeting the RUNX1 gene helps reduce severe skin fibrosis

Skin fibrosis includes hypertrophic scar (HTS), keloid scar (KS), and systemic sclerosis (SSc). These conditions share persistent fibroblast activation, excessive extracellular matrix (ECM) deposition, and progressive skin remodeling.

13 Oct 2026

Light-activated cotton fabric reduces harmful microorganisms in hospital rooms

A team from the Alcoy campus of the Universitat Politècnica de València (UPV), the Research Institute for Chemical Technology (ITQ, CSIC-UPV), the Research Institute for Mediterranean Agroforestry (IAM UPV) and the Joint Research Unit between the UPV and the Health Research Institute at La Fe Hospital in Valencia (UPV-IISLaFe) has developed a new self-disinfecting cotton fabric capable of eliminating bacteria, fungi and viruses in hospital settings using visible light.

13 Oct 2026

Ensuring accessible work environments for disabled physicians may enhance patient care

New research indicates that 5% of practising physicians report a disability "always or often," and another 12% report disability "sometimes." The authors call for action on improving accessibility to ensure equity and sustainability in the physician workforce.

13 Oct 2026

CMAJ analysis urges Canada to pass Safe Social Media Act to protect children

Canada's proposed Safe Social Media Act, which aims to protect children, should be passed, according to an Analysis article in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.261104.

13 Oct 2026

Beyond ‘bad’ cholesterol: new clues to the risk of heart disease

Researchers at Chalmers University of Technology, in Sweden, shed new light on the remaining risk of heart disease, even after the known risk factor of ‘bad’ cholesterol is brought down to a healthy level.

13 Oct 2026