Large Intestine News and Research

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New, "designer" dietary fiber may eliminate side effects of current IBS treatment

A newly-developed, "designer" dietary fiber with an added potential prebiotic effect may eliminate the side effects of current treatment for Irritable Bowel Syndrome which affects 10-20 percent of the population, disproportionately women.

20 Jan 2014

Change in gene expression occurs in patients with "pouchitis" after UC surgery

"Pouchitis" developing after surgery for ulcerative colitis (UC) is associated with changes in gene expression, which increase along with disease severity, reports a study in Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America (CCFA). The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

11 Oct 2013

Colorectal cancer screening in European countries highly effective in reducing mortality

Screening for colorectal cancer in European countries is highly effective in reducing mortality from the disease. Some of the resources currently being devoted to breast and prostate screening programmes, where the evidence of effectiveness is much less clear-cut, should be reallocated to the early detection of CRC, the 2013 European Cancer Congress will hear today (Sunday).

29 Sep 2013

Medical imaging website compiles list of hottest clinical procedures in imaging for AD

AuntMinnie.com, the respected medical imaging website, has compiled a list of the "hottest clinical procedures" in imaging, such as molecular breast imaging and PET scans for Alzheimer's disease.

27 Sep 2013

Study finds low doses of vancomycin to be effective in treating serious C-difficile infection

Clostridium difficile infection (CDI) treatment in a hospital setting using low dose oral vancomycin showed similar effectiveness compared to high dose, according to a new study by researchers at Montefiore Medical Center and Albert Einstein College of Medicine of Yeshiva University.

12 Sep 2013

Antioxidant substances in red wine, dark chocolate, olive oil linked with health benefits

The scientific spotlight focuses today on the healthful antioxidant substances in red wine, dark chocolate, olive oil, coffee, tea, and other foods and dietary supplements that are enticing millions of consumers with the promise of a healthier, longer life.

12 Sep 2013

Researchers pinpoint ways to counter effects of antibiotics-driven depletion of gut-dwelling bacteria

A new study by researchers at the Stanford University School of Medicine could help pinpoint ways to counter the effects of the antibiotics-driven depletion of friendly, gut-dwelling bacteria.

2 Sep 2013

Health benefits of short-chain fructooliogosaccharides

A new presentation today at the 2013 Institute of Food Technologists (IFT) Annual Meeting & Expo in Chicago- focused on the health benefits of short-chain fructooliogosaccharides (scFOS), which are low-calorie, non-digestible carbohydrates that can improve food taste and texture while aiding immunity, bone health and the growth and balance of important bacteria in the digestive track.

17 Jul 2013

Home treatment improves chronic constipation in children

Home treatment with a simple, battery-operated system that applies four sticky electrode patches to the mid-section allowed a group of children with the most difficult-to-treat, possibly congenital, constipation to reduce soiling and improve elimination, according to results presented today at the 11th World Congress of the International Neuromodulation Society.

12 Jun 2013

Simponi injection gets FDA approval to treat adults with ulcerative colitis

The U.S. Food and Drug Administration today approved a new use for Simponi (golimumab) injection to treat adults with moderate to severe ulcerative colitis.

16 May 2013

New device allows automatic suturing of large intestine during cancer colon surgery

The Spanish research centre Innotex has developed a device that enables automatic suturing of the large intestine after being sectioned during cancer colon surgery. The novelty of the system, called Insewing, is that it allows the use of absorbable suture material instead of metallic staples which are currently used and could cause intestinal stiffness and obstruction.

26 Apr 2013

Crohn’s permanent stoma rates plummet in post-biologic era

Permanent stoma creation in patients with extensive Crohn’s disease has fallen to a third of its previous rate following the advent of biologic therapy, research shows.

25 Apr 2013

Researchers use atomic force microscopy technique to read information encoded in gut lining

A new technique based on atomic force microscopy was developed at the Institute of Food Research to help 'read' information encoded in the gut lining.

15 Apr 2013

Lynch syndrome and cancer risk: an interview with Prof. Ellen Kampman, Wageningen University

Lynch syndrome is one of the inherited cancer syndromes characterized by the development of colorectal cancer, endometrial cancer and other cancers at an early age.

10 Apr 2013

FMT treatment improves symptoms in pediatric patients with active ulcerative colitis

A Spectrum Health clinical trial has found that fecal microbial transplantation (FMT) has resulted in the improvement or absence of symptoms in most pediatric patients with active ulcerative colitis.

7 Apr 2013

Investigational treatment for ulcerative colitis (UC) and Crohn’s disease (CD) has Marketing Authorisation Application submitted

Takeda Pharmaceutical Company Limited (“Takeda”) today announced that a Marketing Authorisation Application (MAA) has been submitted to The European Medicines Agency (EMA) for vedolizumab, an investigational, gut-selective humanized monoclonal antibody for the treatment of adults with moderately to severely active ulcerative colitis (UC) and Crohn’s disease (CD), the two most common types of inflammatory bowel disease (IBD).

8 Mar 2013

Genomic Health fourth quarter total revenue increases to $60.4 million

Genomic Health, Inc. today reported financial results and business progress for the quarter and year ended December 31, 2012.

6 Feb 2013

Colorectal cancer screening: an interview with Dr Donato F. Altomare

Colorectal cancer is a malignant neoplasm affecting the large bowel and the rectum mainly after the 5th decade of life and representing the second cause of death for cancer in western countries (the third in women). In about 15-20% of patients there is an inherited predisposition.

29 Jan 2013

Cancer risk independent of folic acid supplementation

Folic acid supplementation does not increase or decrease the risk for cancer, suggests research published in The Lancet.

28 Jan 2013

Calmangafodipir protects against side effects of cancer treatments

A drug developed at Linköping University in Sweden protects against the side effects of cancer treatments while strengthening the effects on the tumour.

22 Jan 2013