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Innate and adaptive immune responses to SARS-CoV-2 infection in older golden hamsters

Researchers assessed the variation in SARS-CoV-2 manifestation with age.

13 Jun 2022

A comparison of SARS-CoV-2 and influenza cytokine storms

In a recent study published in the Journal of Interferon & Cytokine Research, researchers compared the cytokine storms of pandemic influenza and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

9 Jun 2022

Study sheds new light on the role of transcription factors in bone marrow microenvironments

In your home, storing books on a bookshelf, tools in a tool box, and a broom in a broom cupboard makes it easy to access these items whenever you need them.

9 Jun 2022

Molecular modeling techniques describe the process of interaction between nanotubes and the main structures of SARS-CoV-2

Researchers assessed the interactions between carbon nanotubes and SARS-CoV-2.

7 Jun 2022

Substances touted to improve athletic performance and high fat diet fuel pancreatic cancer’s development

Researchers at the University of Michigan Rogel Cancer Center have found a cell nuclear receptor activated by high fat diets and synthetic substances in unregulated athletic performance enhancers fuels the progression of precancerous pancreas lesions into pancreatic cancer.

1 Jun 2022

Tracking the emergence of potential drug-resistant mutations in SARS-CoV-2 proteins

Researchers hypothesized that the emergence of resistant SARS-CoV-2 variants can be anticipated by identifying possible escape mutations already present in the existing SARS-CoV-2 populations.

1 Jun 2022

Structural and biochemical traits of main protease-mediated SARS-CoV-2 polyprotein processing

A recent article illustrated the structural and biochemical characteristics of the processing of SARS-CoV-2 polyproteins by Mpro.

1 Jun 2022

The pineapple-derived jacalin-related lectin as a potential anti-SARS-CoV-2 agent

Scientists demonstrated that the pineapple-derived jacalin-related lectin (AcmJRL/AnLec) could be an anti-SARS-CoV-2 agent.

31 May 2022

Researchers report novel interactions between the SARS-CoV-2 S protein and estrogen receptor alpha

Researchers profiled the binding sites of the entire SARS-CoV-2 spike protein sequence.

26 May 2022

Immunogenicity predictions reveal SARS-CoV-2 CD8+ T-cell epitopes

In a recent study posted to the bioRxiv* pre-print server, researchers identified several new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epitopes displayed on human leukocyte antigens class I (HLA-I) molecules.

26 May 2022

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

A recent study posted to the bioRxiv* preprint server illustrated that specific chemokine antibodies aid in recognizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) convalescent individuals with a desirable disease course.

26 May 2022

Olverembatinib a potent inhibitor of Omicron NTD-mediated cytokine release

Researchers determine whether mutations in the Omicron NTD influence its potential to stimulate myeloid cells and enhance inflammatory cytokine release.

22 May 2022

Blood-based biomarker can predict the benefit of immunotherapy to lung cancer patients

A blood-based tumor biomarker can predict the benefit of immunotherapy to patients with non-small cell lung cancer, according to a study published in Nature Medicine.

20 May 2022

Natural immunity weak and short-lived in unvaccinated after Omicron infection

In a recent study posted to the journal Nature, researchers showed that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron infection without SARS-CoV-2 vaccination conferred poor cross-variant neutralizing capacities.

20 May 2022

RGS2 protein expression may explain reduced sense of smell in COVID

Researchers tested the hypothesis that anosmia in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected individuals elevates the expression of the odorant receptor, a regulator of G protein signaling 2 (RGS2) in humans.

18 May 2022

Exosomes derived from γδ-T cells synergized with radiotherapy can control nasopharyngeal carcinoma

A research team at LKS Faculty of Medicine, The University of Hong Kong discovered that exosomes derived from γδ-T cells (γδ-T-Exos) synergised with radiotherapy can control nasopharyngeal carcinoma (NPC) by overcoming the radioresistance of NPC cancer stem cells (CSCs) and preserve their tumor-killing and T cell-promoting activities in the immunosuppressive NPC microenvironment.

18 May 2022

Development of a novel surface plasmon resonance-based assay to determine kinetics of SARS-CoV-2 spike – human ACE2 interaction

A team of scientists has recently studied the kinetic and thermodynamic characteristics of interaction between human ACE2 and spike receptor-binding domains of different variants of SARS-CoV-2.

13 May 2022

Ligand News and Research

Innate and adaptive immune responses to SARS-CoV-2 infection in older golden hamsters

A comparison of SARS-CoV-2 and influenza cytokine storms

Study sheds new light on the role of transcription factors in bone marrow microenvironments

Molecular modeling techniques describe the process of interaction between nanotubes and the main structures of SARS-CoV-2

Substances touted to improve athletic performance and high fat diet fuel pancreatic cancer’s development

Tracking the emergence of potential drug-resistant mutations in SARS-CoV-2 proteins

Structural and biochemical traits of main protease-mediated SARS-CoV-2 polyprotein processing

The pineapple-derived jacalin-related lectin as a potential anti-SARS-CoV-2 agent

Researchers report novel interactions between the SARS-CoV-2 S protein and estrogen receptor alpha

Immunogenicity predictions reveal SARS-CoV-2 CD8+ T-cell epitopes

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

Olverembatinib a potent inhibitor of Omicron NTD-mediated cytokine release

Blood-based biomarker can predict the benefit of immunotherapy to lung cancer patients

Natural immunity weak and short-lived in unvaccinated after Omicron infection

RGS2 protein expression may explain reduced sense of smell in COVID

Exosomes derived from γδ-T cells synergized with radiotherapy can control nasopharyngeal carcinoma

Development of a novel surface plasmon resonance-based assay to determine kinetics of SARS-CoV-2 spike – human ACE2 interaction

Study reveals serum proteomic signatures of long COVID patients

The promise of RNA medicine is targeted and personalized

Discovery of host co-factors necessary for SARS-CoV2 infection

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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