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AKAP protein alterations implicated in bipolar disorder

Researchers have found increased cellular expression of the postsynaptic signaling protein AKAP5/79 in the anterior cingulate cortex of patients with bipolar disorder.

8 Mar 2013

Brown University develops new implantable and rechargeable wireless brain sensor

A team of neuroengineers based at Brown University has developed a fully implantable and rechargeable wireless brain sensor capable of relaying real-time broadband signals from up to 100 neurons in freely moving subjects.

28 Feb 2013

Cortisol and white matter integrity relationship disrupted in bipolar disorder

Researchers have found evidence in support of hypercortisol-induced glial dysfunction affecting periventricular white matter integrity in patients with bipolar disorder.

14 Feb 2013

Four-step process delivers specific, reliable clinical rules

Dutch researchers have developed a four-step strategy for formulating clinical decision support systems, which they say could help reduce “alert fatigue.”

7 Feb 2013

Fifteen established scientists to receive NARSAD Distinguished Investigator Grants

The Brain & Behavior Research Foundation (formerly NARSAD, the National Alliance for Research on Schizophrenia and Depression) announced the latest recipients of its highly competitive NARSAD Distinguished Investigator Grants.

16 Jan 2013

Psychologic treatment has long-term benefits for bipolar patients

Psychoeducation and cognitive behavioral therapy combined with pharmacologic treatment provides significant long-term benefits for patients with refractory bipolar disorder, researchers report.

8 Jan 2013

Merck’s resubmission of the NDA for suggammadex sodium injection accepted for review by the FDA

Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced that the resubmission of the New Drug Application (NDA) for sugammadex sodium injection has been accepted for review by the U.S. Food and Drug Administration (FDA). Merck expects the FDA’s review to be completed in the first half of 2013.

7 Jan 2013

Psychologic treatment has long-term benefits for bipolar patients

Psychoeducation and cognitive behavioral therapy combined with pharmacologic treatment provides significant long-term benefits for patients with refractory bipolar disorder, researchers report.

4 Jan 2013

New Spectra Iris indirect ophthalmoscope from Keeler

Spectra Iris is a new addition to Keeler's indirect ophthalmoscope range. It has been specifically designed as a compact, lightweight and portable indirect with an adjustable aperture for all pupil sizes.

20 Dec 2012

ADHD comorbidity confounds brain findings in bipolar disorder

Structural brain abnormalities found in patients with bipolar disorder may have been wrongly attributed to the condition and in fact be associated with comorbid attention–deficit hyperactivity disorder, US researchers believe.

7 Dec 2012

Researchers discover new cause of hydrocephalus

Researchers at the University of Iowa have discovered a new cause of hydrocephalus, a devastating neurological disorder that affects between one and three of every 1,000 babies born. Working in mice, the researchers identified a cell signaling defect, which disrupts immature brain cells involved in normal brain development.

20 Nov 2012

Brain's infralimbic cortex can switch between new and old habits

Habits are behaviors wired so deeply in our brains that we perform them automatically. This allows you to follow the same route to work every day without thinking about it, liberating your brain to ponder other things, such as what to make for dinner.

1 Nov 2012

FDA accepts Sunovion’s two LATUDA sNDAs for review

Sunovion Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration (FDA) has accepted for review two supplemental New Drug Applications (sNDAs) for the use of LATUDA as 1) monotherapy and 2) adjunctive therapy to lithium or valproate, both to treat adult patients with depressive episodes associated with bipolar I disorder (bipolar depression).

31 Oct 2012

Study shows how NCAN gene results in manic symptoms of bipolar disorder

Flying high, or down in the dumps - individuals suffering from bipolar disorder alternate between depressive and manic episodes. Researchers from the University of Bonn and the Central Institute of Mental Health in Mannheim have now discovered, based on patient data and animal models, how the NCAN gene results in the manic symptoms of bipolar disorder. The results have been published in the current issue of "The American Journal of Psychiatry."

1 Sep 2012

Scientists create synthetic pores that mimic activity of cellular ion channels

Inspired by nature, an international research team has created synthetic pores that mimic the activity of cellular ion channels, which play a vital role in human health by severely restricting the types of materials allowed to enter cells.

18 Jul 2012

Longer looks: Keeping Parkinson's a secret

When Nancy Mulhearn learned she had Parkinson's disease seven years ago, she kept the diagnosis mostly to herself, hiding it from friends, colleagues -- even, at first, her mother, sister and teenage children. After seven months, she decided she had to tell her family, and they settled into an unspoken agreement not to talk about the disease.

13 Jul 2012

TNF-α levels linked to lithium response in BD patients

Patients with bipolar disorder who have a poor response to lithium treatment have significantly higher serum levels of tumor necrosis factor-α than those with a good response, researchers report.

10 Jul 2012

High medical illness rates in bipolar disorder

Results from a US study show that more than half of patients with bipolar disorder have a significant burden of comorbid medical illnesses.

28 Jun 2012

MIT engineers develop new glucose-powered implantable medical device

MIT engineers have developed a fuel cell that runs on the same sugar that powers human cells: glucose. This glucose fuel cell could be used to drive highly efficient brain implants of the future, which could help paralyzed patients move their arms and legs again.

14 Jun 2012

Study finds more than three-fourths of battery-related visits to ED by children

In today's technology-driven world, batteries, especially button batteries, are everywhere. They power countless gadgets and electronic items that we use every day. While they may seem harmless, button batteries can be dangerous if swallowed by children.

15 May 2012