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AI tool predicts metastatic risk in multiple cancers

Why do some tumors spread while others remain localized? The mechanisms governing the metastatic potential of tumor cells remain largely unknown — yet understanding this is crucial for optimizing patient care.

22 Jan 2026

Purdue-developed LENN system enhances stability and targeting of mRNA cancer therapies

Published, peer-reviewed research shows a patent-pending, virus-mimicking platform technology developed at Purdue University improves upon traditional methods of targeting bladder cancer cells with messenger RNA (mRNA) therapies.

16 Jan 2026

Study provides a new paradigm for managing transplant‑related immune complications

Acute graft-versus-host disease (aGVHD) is one of the most serious complications after allogeneic hematopoietic stem cell transplantation (allo‑HSCT).

16 Jan 2026

Scientists uncover promising therapeutic target for autoimmune disease affecting the brain

Scientists have identified a promising target for treatment of a devasting autoimmune disease affecting the brain.

14 Jan 2026

CRISPR-Cas3: A safer gene-editing tool shows promise for transthyretin amyloidosis treatment

Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin amyloidosis (ATTR) is a progressive disorder involving amyloid deposits of misfolded transthyretin (TTR) proteins.

14 Jan 2026

RAS-MAPK inhibition halts spinal deformity in neurofibromatosis type 1 mouse model

Spinal deformities such as scoliosis and kyphosis are among the most serious complications of neurofibromatosis type 1 (NF1), a genetic disorder that affects about one in 3,000 people.

14 Jan 2026

Cannabidiol could become a therapeutic tool for fetal alcohol spectrum disorder

Cannabidiol (CBD) could become a therapeutic tool to address some of the most frequent and disabling consequences of fetal alcohol spectrum disorder (FASD), a condition caused by alcohol exposure during pregnancy.

14 Jan 2026

New mouse model enables study of chronic lung infections in aging

Respiratory infections are among the leading causes of illness and death in the elderly, driven by immune aging, chronic diseases, and reduced physiological resilience.

13 Jan 2026

Ultrasound-responsive nanocatchers enable precise in-situ tumor antigen capture

Professor Zhaohui Tang and Associate Professor Zhilin Liu from the team of Professor Xuesi Chen at the Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, developed ultrasound-responsive in-situ antigen nanocatchers (S-nanocatchers), achieving precise spatiotemporal capture of tumor antigens and controllable acquisition of in-situ vaccines.

9 Jan 2026

Scientists identify a molecular switch that controls water flow in the gut

Although constipation and diarrhea may seem like opposite problems, they both hinge on the same underlying issue: how much fluid moves into the gut. These common issues affect millions of people in the U.S. each year, yet scientists have not fully understood what regulates intestinal fluid balance.

9 Jan 2026

Exposure to micro- and nanoplastics linked to rising number of people with chronic IBD

A research team led by the Medical University of Vienna and the University of Vienna has investigated a possible link between the rising number of people with chronic inflammatory bowel disease and the increasing exposure to micro- and nanoplastics (MNPs).

8 Jan 2026

Injectable nanomaterial reduces secondary brain injury after ischemic stroke

When a person suffers a stroke, physicians must restore blood flow to the brain as quickly as possible to save their life.

7 Jan 2026

Gene therapy breakthrough could provide hope for millions living with chronic pain

A preclinical study uncovered a new gene therapy that targets pain centers in the brain while eliminating the risk of addiction from narcotics treatments, a breakthrough which could provide hope for the more than 50 million Americans living with chronic pain.

7 Jan 2026

Mouse Model News and Research

AI tool predicts metastatic risk in multiple cancers

Purdue-developed LENN system enhances stability and targeting of mRNA cancer therapies

Study provides a new paradigm for managing transplant‑related immune complications

Scientists uncover promising therapeutic target for autoimmune disease affecting the brain

CRISPR-Cas3: A safer gene-editing tool shows promise for transthyretin amyloidosis treatment

RAS-MAPK inhibition halts spinal deformity in neurofibromatosis type 1 mouse model

Cannabidiol could become a therapeutic tool for fetal alcohol spectrum disorder

New mouse model enables study of chronic lung infections in aging

Ultrasound-responsive nanocatchers enable precise in-situ tumor antigen capture

Scientists identify a molecular switch that controls water flow in the gut

Exposure to micro- and nanoplastics linked to rising number of people with chronic IBD

Injectable nanomaterial reduces secondary brain injury after ischemic stroke

Gene therapy breakthrough could provide hope for millions living with chronic pain

New breakthrough could modernize treatment for glioblastoma

Simple drug treatments could help older brains cope with memory decline and postoperative recovery

Irregular collagen in uterine scars linked to placenta accreta development

Study uncovers a possible biomarker linked to MS disease progression

Inflammation and immune suppression fuel aggressive SCLC behavior and spread

Reframing the role of MCL1 in cancer signaling and metabolism

A senescence-based therapeutic approach for temporal lobe epilepsy

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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