Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Breakthrough in predicting Parkinson’s and dementia in people with REM sleep behavior disorder

An international research team led by Université de Montréal medical professor Shady Rahayel has made a major breakthrough in predicting neurodegenerative diseases.

26 Sep 2025

UdeM studies make a major breakthrough in predicting neurodegenerative diseases

An international research team led by Université de Montréal medical professor Shady Rahayel has made a major breakthrough in predicting neurodegenerative diseases.

25 Sep 2025

Scientists map step-by-step activation of brain receptors

When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, know that even slight changes in their activity level can mean the difference between normal function and serious neurological disorders.

24 Sep 2025

Menopause found to shape initial symptoms and comorbidities in multiple sclerosis

New research presented today at the 41st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS 2025) reveals that menopause may significantly influence how multiple sclerosis (MS) first presents in women, as well as the types of associated health conditions they experience.

24 Sep 2025

Blood and brain biomarkers transform how doctors confirm Alzheimer’s disease

A new Lancet review proposes a three-wave diagnostic pathway that combines clinical expertise with blood, CSF, and PET biomarkers. This approach aims to deliver earlier, more accurate, and more equitable Alzheimer’s disease diagnosis worldwide.

24 Sep 2025

How food choices and cooking methods drive brain inflammation and disease

Researchers reviewing evidence in NeuroSci show how dietary AGEs and their interaction with RAGE drive oxidative stress, inflammation, and neurodegeneration. They highlight how cooking methods and diet choices could lower AGE burden and protect brain health, while calling for rigorous clinical trials.

24 Sep 2025

Advanced imaging exposes breakdown in brain cell communication linked to Alzheimer’s

Research led by The Ohio State University Wexner Medical Center and College of Medicine explores the ways brain cells communicate, revealing fresh insight into the progression of Alzheimer's disease.

18 Sep 2025

Contact sports tied to hidden brain damage independent of CTE

This fall, tens of millions of people will be at risk for chronic traumatic encephalopathy (CTE), a degenerative brain disease caused by repeated head impacts from contact sports like football, soccer, and ice hockey, or military service.

17 Sep 2025

Repetitive head impacts trigger early brain changes in young athletes

Research supported by the National Institutes of Health (NIH) shows that repeated head impacts from contact sports can cause early and lasting changes in the brains of young- to middle-aged athletes.

17 Sep 2025

High fat diet impairs memory formation through autophagy dysfunction

Modern lifestyles and dietary changes have significantly increased the consumption of high-fat foods, contributing to a steep rise in the prevalence of obesity, diabetes, and metabolic disorders.

17 Sep 2025

Stem cell therapy restores brain function after stroke

Stem cell transplantation can reverse stroke damage, researchers at the University of Zurich report. Its beneficial effects include regeneration of neurons and restoration of motor functions, marking a milestone in the treatment of brain disorders.

16 Sep 2025

Boosting PI31 to restore synaptic function and prevent neurodegeneration

One fundamental feature of neurodegenerative diseases is a breakdown in communication. Even before brain cells die, the delicate machinery that keeps neurons in touch-by clearing away protein waste at the synapses-starts to fail.

16 Sep 2025

Novel vitamin K analogs show promise for reversing neurodegenerative diseases

Neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's disease are characterized by the progressive loss of neurons.

13 Sep 2025

Genetic mutation in some East Asians linked to aldehyde storm and increased liver disease risk

Researchers have identified the mechanism by which a common genetic mutation increases liver disease risk. Their findings suggest that healthy choices, such as increasing antioxidants and limiting exposure to smoke, may reduce the risk of this disease.

13 Sep 2025

CRISPR-based therapeutic approach designed to treat fatal pediatric disease

Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood.

11 Sep 2025

Special MRI technique predicts onset of mild cognitive impairment and cognitive decline

A special MRI technique that detects iron levels in different regions of the brain can predict the onset of mild cognitive impairment and cognitive decline in cognitively unimpaired older adults, potentially creating a pathway to earlier interventions, according to a study published today in Radiology, a journal of the Radiological Society of North America.

9 Sep 2025

Study finds possible molecular connection between air pollution and Lewy body dementia risk

A team of researchers found there is a possible molecular connection between air pollution and an increased risk of developing Lewy body dementia.

4 Sep 2025

Impaired spatial orientation found in older adults at risk for Alzheimer’s disease

Individuals with an increased risk for dementia due to Alzheimer's disease can have impaired spatial orientation skills.

3 Sep 2025

Can honey protect your brain? Study reviews its potential against Alzheimer's

This review examined 27 preclinical studies on honey and Alzheimer’s disease, showing honey’s bioactive compounds counter oxidative stress, inflammation, and amyloid buildup. Despite promising lab results, no human trials exist, underscoring the need for clinical research.

1 Sep 2025

How plant compounds could target Alzheimer’s disease from multiple angles

This review highlights how dietary polyphenols modulate Alzheimer’s disease biology through antioxidant, anti-inflammatory, and multi-target mechanisms, supported by in-silico docking analyses. Despite promise, challenges in bioavailability and brain delivery remain key hurdles to clinical translation.

31 Aug 2025

Neurodegeneration News and Research

Further Reading

Breakthrough in predicting Parkinson’s and dementia in people with REM sleep behavior disorder

UdeM studies make a major breakthrough in predicting neurodegenerative diseases

Scientists map step-by-step activation of brain receptors

Menopause found to shape initial symptoms and comorbidities in multiple sclerosis

Blood and brain biomarkers transform how doctors confirm Alzheimer’s disease

How food choices and cooking methods drive brain inflammation and disease

Advanced imaging exposes breakdown in brain cell communication linked to Alzheimer’s

Contact sports tied to hidden brain damage independent of CTE

Repetitive head impacts trigger early brain changes in young athletes

High fat diet impairs memory formation through autophagy dysfunction

Stem cell therapy restores brain function after stroke

Boosting PI31 to restore synaptic function and prevent neurodegeneration

Novel vitamin K analogs show promise for reversing neurodegenerative diseases

Genetic mutation in some East Asians linked to aldehyde storm and increased liver disease risk

CRISPR-based therapeutic approach designed to treat fatal pediatric disease

Special MRI technique predicts onset of mild cognitive impairment and cognitive decline

Study finds possible molecular connection between air pollution and Lewy body dementia risk

Impaired spatial orientation found in older adults at risk for Alzheimer’s disease

Can honey protect your brain? Study reviews its potential against Alzheimer's

How plant compounds could target Alzheimer’s disease from multiple angles

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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