VEGF News and Research

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VEGF is a substance made by cells that stimulates new blood vessel formation. Also called vascular endothelial growth factor.

Novel approach uses magnetic beads for the treatment of preeclampsia

Preliminary laboratory tests show that functionalized magnetic beads successfully reduced blood levels of a harmful molecule that is elevated during preeclampsia, according to new research in the American Heart Association's journal Hypertension.

13 May 2019

'Eye-in-a-dish' model reveals genetic variants that may contribute to AMD

Age-related macular degeneration is one of the most common causes of vision loss in people over age 65.

10 May 2019

A new strategy for managing diabetic macular edema in people with good vision

A change to the approach for treating diabetic macular edema may be on the way, thanks to a study published today in the Journal of the American Medical Association.

2 May 2019

Experimental drug may be twice as good at fighting vision loss as previously thought

In studies with lab-grown human cells and in mice, Johns Hopkins Medicine researchers have found that an experimental drug may be twice as good at fighting vision loss as previously thought.

11 Apr 2019

Gene medication shows promise to treat spinal cord injuries

The two-gene medication has been proven to recover motor functions in rats. After several months of treatment, rodents were able to use previously paralyzed limbs. Researchers at Kazan Federal University are now seeking pre-clinical trial investment.

18 Mar 2019

Study suggests new approach to ameliorating obesity-associated metabolic abnormalities

The search by scientists to find ways to combat obesity continues. Recently, investigators have been exploring whether they can engage the lymphatic system to help regulate obesity-induced inflammation of fat (adipose) tissue and restore systemic metabolic fitness.

14 Mar 2019

Study shows therapeutic potential of VEGF-A mRNA for regenerative angiogenesis in humans

An international team of researchers from academia and the biopharma industry has published a Phase 1a/b study, showing the therapeutic potential of mRNA encoding for vascular endothelial growth factor A (VEGF-A) for regenerative angiogenesis in humans.

20 Feb 2019

Lab model reveals the formation of new blood vessels

To provide sufficient oxygen to tissues and organs within the body, blood vessels need to sprout new offshoots to form a widespread blood supply network, much like the trunk, branches, and twigs of a tree.

31 Jan 2019

Complex interplay of two growth factors key to fast-acting antidepressant actions

A study by researchers at Yale University reveals a complex interplay of two different growth factors in the rapid and long-lasting antidepressant effects of ketamine.

31 Jan 2019

FOTIVDA expected to be included in new ESMO guidelines for advanced renal cell carcinoma

EUSA Pharma welcomes the news that FOTIVDA (tivozanib) is expected to be included in the upcoming European Society of Medical Oncology clinical practice guidelines for advanced renal cell carcinoma, anticipated to be published at the end of this year.

22 Oct 2018

$Phase III LONSURF study shows progression-free survival in patients with refractory metastatic gastric cancer$

Phase III LONSURF study shows progression-free survival in patients with refractory metastatic gastric cancer

Servier and Taiho Oncology, Inc. (U.S.), a subsidiary of Taiho Pharmaceutical Co., Ltd. (Japan), jointly announced today clinical data from the pivotal Phase III TAS-102 Gastric Study (TAGS) evaluating LONSURF® (trifluridine/tipiracil, TAS-102) versus placebo and best supportive care in patients with heavily pre-treated metastatic gastric cancer who have progressed or are intolerant to previous lines of therapy.

22 Oct 2018

Multi-strain probiotic helps reduce chemotherapy-induced diarrhea in cancer patients

A high concentration of multi-strain probiotic helps to reduce mild to moderate episodes of chemotherapy-induced diarrhea in cancer patients, according to results of a phase II/III study in India.

22 Oct 2018

Exelixis presents CABOSUN and METEOR trial results in patients with advanced renal cell carcinoma

Exelixis, Inc. today announced results from two analyses evaluating the effect of PD-L1 expression or prior treatment with immune checkpoint inhibitors on the efficacy of cabozantinib in patients with advanced renal cell carcinoma (RCC). The findings are being presented this week at the European Society for Medical Oncology 2018 Congress being held October 19-23 in Munich, Germany.

22 Oct 2018

Immunotherapy medicine found to be effective in treating uveitis

A team of researchers from the UCH CEU's Biomedical Sciences Institute has tested the efficiency of Bevacizumab, medicine used against cancer and in ophtalmology, to treat uveítis, thus stopping the inflammation from spreading.

19 Oct 2018

TGen-UNM consortium awarded NIH grant to discover new treatments for diabetic blindness

Diabetes is an increasing global epidemic that is expected to grow by more than 50 percent in the next two decades, leaving more than half a billion patients worldwide exposed to potentially life-altering medical complications, including pain and numbness in the feet, lost limbs, life-threatening disorders of the heart, liver and kidneys -- and even blindness.

26 Sep 2018

CHMP provides positive opinion to Cabometyx for previously-treated patients with hepatocellular carcinoma

Ipsen announced today that the Committee for Medicinal Products for Human Use, the scientific committee of the European Medicines Agency, provided a positive opinion for Cabometyx (cabozantinib) as a monotherapy for the treatment of hepatocellular carcinoma in adults who have been previously treated with sorafenib.

21 Sep 2018

Ipsen receives approval from Health Canada for CABOMETYX tablets for treating renal cell carcinoma

Exelixis, Inc. today announced that its partner Ipsen Biopharmaceuticals Canada Inc. received approval from Health Canada of CABOMETYX® tablets for the treatment of adults with advanced renal cell carcinoma who have received prior vascular endothelial growth factor targeted therapy.

19 Sep 2018

VEGF News and Research

Further Reading

Novel approach uses magnetic beads for the treatment of preeclampsia

'Eye-in-a-dish' model reveals genetic variants that may contribute to AMD

A new strategy for managing diabetic macular edema in people with good vision

Experimental drug may be twice as good at fighting vision loss as previously thought

Gene medication shows promise to treat spinal cord injuries

Study suggests new approach to ameliorating obesity-associated metabolic abnormalities

Study shows therapeutic potential of VEGF-A mRNA for regenerative angiogenesis in humans

Lab model reveals the formation of new blood vessels

Complex interplay of two growth factors key to fast-acting antidepressant actions

FOTIVDA expected to be included in new ESMO guidelines for advanced renal cell carcinoma

Phase III LONSURF study shows progression-free survival in patients with refractory metastatic gastric cancer

Multi-strain probiotic helps reduce chemotherapy-induced diarrhea in cancer patients

Exelixis presents CABOSUN and METEOR trial results in patients with advanced renal cell carcinoma

Immunotherapy medicine found to be effective in treating uveitis

TGen-UNM consortium awarded NIH grant to discover new treatments for diabetic blindness

CHMP provides positive opinion to Cabometyx for previously-treated patients with hepatocellular carcinoma

Ipsen receives approval from Health Canada for CABOMETYX tablets for treating renal cell carcinoma

Study: aPKC inhibitors may provide new therapeutic option for blinding eye diseases

NCCN updates Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets

Additional inhibitor could be key to helping anti-VEGF therapies overcome resistance in glioblastoma

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