Whole Genome Sequencing News and Research

RSS

Study concludes a single intramuscular injection of adintrevimab provides prophylactic efficacy against COVID-19 without safety concerns

Researchers evaluated the prophylactic immune protection conferred by a single intramuscular injection of adintrevimab (ADG20) against symptomatic COVID-19.

16 Jun 2023

Mapping the evolutionary timeline and population distribution of E. coli’s protective outer capsule

In a new study, published today (15 June) in Nature Communications, a multi-centre team led by the Wellcome Sanger Institute, the University of Oslo, Imperial College London and UCL, has mapped for the first time the evolutionary timeline and population distribution of Escherichia coli’s protective outer capsule, which is responsible for the bacterium’s virulence.

15 Jun 2023

SickKids scientists shine light on the complex genetics that underlie blood pressure regulation

Scientists at The Hospital for Sick Children (SickKids) are delving deep into the non-coding genome to unravel the complex genetics that underlie blood pressure regulation and hypertension (high blood pressure) – the leading cause of cardiovascular disease affecting 1.25 billion people worldwide.

6 Jun 2023

Escherichia coli ST2797 as a novel emerging extended-spectrum beta-lactamase Escherichia coli

Researchers suggest that Escherichia coli ST2797 could potentially be a new type of extended-spectrum beta-lactamase (ESBL) Escherichia coli.

5 Jun 2023

Multi-ethnic genome study unlocks new genetic links to health conditions

Research explores the genetic architecture of circulating metabolites, uncovering novel variant-metabolite associations and validating previous findings. It provides insights into the genetic contribution to metabolite levels and potential implications for human disease.

31 May 2023

New variants of human metapneumovirus surge in Spain post-COVID, highlighting evolution and impact

Investigating Human metapneumovirus (HMPV) prevalence, genetic diversity, and evolution in respiratory tract infections (RTIs) for better understanding and management.

31 May 2023

Identifying what makes some gut bacteria strains life-threatening in pre-term babies

Researchers from the Quadram Institute and University of East Anglia have identified what makes some strains of gut bacteria life-threatening in pre-term babies.

25 May 2023

Statistical modeling based of Australian native possum excreta identifies locations of Buruli ulcer occurrence in humans

The study aimed to predict the future human Buruli ulcer case locations via statistical modelling.

25 May 2023

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

Researchers analyzed data from three SARS-CoV-2 outbreaks among nursing homes in Belgium.

24 May 2023

Genetic insights unveil promising therapeutic targets for critical COVID-19

Critical COVID-19 illness reveals genetic associations with immunomodulatory therapies, as identified in a comprehensive analysis of 24,202 cases. This study uncovers novel genome-wide significant associations, highlighting potential druggable targets for inflammatory signaling, immunometabolism, and viral replication, offering insights into therapeutic implications.

21 May 2023

Identify the underlying mechanism associated with the initiation of focal amplification in breast cancer

Identifying the underlying mechanism associated with the initiation of focal amplification in breast cancer.

19 May 2023

A novel approach to quantify personal information contained within gut metagenome data

Researchers used shotgun sequencing to extract human reads from DNA in fecal samples

17 May 2023

Rapid spread of antibiotic-resistant E. coli across Europe raises concerns

Research paper highlights the swift cross-border emergence of NDM-5-producing Escherichia coli in the European Union/European Economic Area from 2012 to June 2022. The findings emphasize the need for continued surveillance and effective measures to combat the spread of antibiotic-resistant bacteria.

15 May 2023

The African Personalized Medicine Agenda

In this interview, Rizwana Mia, the Senior Program Manager at South African Medical Research Council, talks to News Medical about the African personalized medicine agenda.

From MGI 4 May 2023

Rising bovine brucellosis outbreaks in Israel threaten dairy farms, public health

Researchers analyze Brucella melitensis outbreaks that affected dairy farms in Israel from 2006 to 2021.

2 May 2023

Genome-based surveillance offers new hope in the fight against healthcare-associated infections

Researchers discuss major healthcare-associated pathogens, as well as current and future public health priorities related to these microorganisms.

2 May 2023

Heterogeneity of autism makes clinical trials difficult, says CHLA expert

Each year in the U.S. the incidence of autism spectrum disorder increases, yet the number of medications to treat the core features of autism remains stuck at zero.

28 Apr 2023

NVX-CoV2373 COVID vaccine safe and effective in preventing COVID-19 in adolescent

Research reports the results of a phase 3 clinical trial evaluating the safety, immunogenicity, and efficacy of the NVX-CoV2373 vaccine in adolescents aged 12 to 17 years. The study found that the vaccine was safe, immunogenic, and efficacious in preventing COVID-19, including the Delta variant, in adolescents.

27 Apr 2023

MGI and South Australian genomics centre introduce DNBSEQ-T7 to supercharge genomics research in Australia

Brisbane, Australia 27th April 2023 - MGI and South Australian Genomics Centre (SAGC) are proud to announce their joint efforts to advance genomics research in Australia by introducing the country's first commercial ultra-high throughput sequencer DNBSEQ-T7*, through MGI's local distributor Decode Science.

From MGI 27 Apr 2023

Study identifies an unknown SARS-CoV-2 lineage on three mink farms in Poland

Researchers detected a cryptic severe acute respiratory syndrome coronavirus 2 lineage on mink farms in Poland.

24 Apr 2023