Antiretroviral News and Research

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Stopping antiretroviral therapy in HIV-infected patients could be beneficial

Stopping antiretroviral therapy in HIV-infected patients from time to time could reduce the side effects and costs of the treatment, according to a study in this week's issue of The Lancet.

3 Aug 2006

Highly active antiretroviral therapy for HIV remains successful

A decade after the introduction of highly active antiretroviral therapy (HAART) for HIV infection in Europe and North America, the risk of AIDS and death remains low for those starting treatment.

3 Aug 2006

Implications of the new Medicare Part D prescription drug benefit for people with HIV/AIDS

The Kaiser Family Foundation today released a report on the implications of the new Medicare Part D prescription drug benefit for people with HIV/AIDS.

3 Aug 2006

Darunavir - first molecule to treat drug-resistant HIV

Doctors have their first FDA-approved tool to treat drug-resistant HIV thanks to a new molecule created by a Purdue University researcher.

2 Aug 2006

Practical advice and individualized attention can help people with HIV stick to a consistent drug regimen

The studies were too different to combine results, but the review team found that the most successful programs emphasized "practical medicine management," one-on-one attention or a 12-week or longer duration.

2 Aug 2006

HIV mutation clue to why only some people develop AIDS dementia

The study of 18 HIV-positive subjects shows that HIV in the brain and central nervous system is genetically different from HIV that lives in the blood and peripheral tissues.

26 Jul 2006

Going to court to get access to essential medicines should only be used as a last resort

Going to court to get access to essential medicines may be necessary and has been successful in several cases, but it should only be used as a last resort, according to an article in this week's issue of The Lancet.

21 Jul 2006

Highly active antiretroviral therapies associated with reduced infections in HIV-infected children

Since the introduction of highly active antiretroviral therapies, there has been a substantial reduction of opportunistic infections and other infections in HIV-infected children, such as pneumonia and tuberculosis.

19 Jul 2006

Clinton Foundation seals deal in Nigerian AIDS fight

The Clinton Foundation, an AIDS charity set up by former U.S. President Bill Clinton, has signed a deal with Nigeria to make cheap AIDS drugs available to fight the disease in Africa's most populous nation.

18 Jul 2006

FDA approves Atripla three-drug combination tablet for treatment of HIV-1

FDA approves Atripla Tablets, a fixed-dose combination of three widely-used antiretroviral drugs.

12 Jul 2006

3-drug pill will help fight HIV/AIDS

The Food and Drug Administration (FDA) in the U.S. has granted approval for a three-ingredient fixed dose tablet for use as an antiretroviral treatment for human immunodeficiency virus (HIV-1) infection in adults.

3 Jul 2006

FDA gives tentative approval for generic pediatric AIDS drug

The Food and Drug Administration (FDA) today announced the tentative approval of the generic version of Abacavir Sulfate Oral Solution.

27 Jun 2006

FDA approves Prezista (darunavir)

FDA approves Prezista (darunavir), a new drug for adults whose infection with the human immunodeficiency virus (HIV) has not responded to treatment with other antiretroviral drugs.

26 Jun 2006

$21 billion for HIV/AIDS, is it paying off?

This year, the U.S. federal government will spend $21 billion for HIV/AIDS research, treatment, prevention, and related activities. Is this enormous expenditure paying off?

1 Jun 2006

FDA gives tentative approval to new generic AIDS drug

The Food and Drug Administration (FDA) today announced the tentative approval of generic abacavir sulfate tablets manufactured by Aurobindo Pharma LTD. of Hyderabad, India.

18 May 2006

Important insights into how cells regulate certain growth-proteins

Researchers here have discovered a new mechanism used by cells - and manipulated by retroviruses - to control the making of certain essential proteins, including some involved in cancer.

8 May 2006

New study describes molecular basis of NeuroAIDS

Using multi-disciplinary analysis that included cognitive, neurophysiologic, virologic, and molecular techniques, the team found both a low-level viral infection in the brain and immune cells that had infiltrated the brain in order to protect against the virus.

3 May 2006

Outcome of patients with hepatitis B and HIV infections referred for liver transplantation

A new study on HIV patients who also had Hepatitis B virus (HBV) found that better outcomes are possible if they are referred early for transplant and treated with a combination of drugs for HBV. It is essential to monitor the HBV status of these patients, however, in order to control the emergence of drug-resistant HBV infection.

3 May 2006

'Resonance' may be the reason for virologic failure in STI drug therapy

Researchers have been puzzled over why HIV-positive patients who have periodic, built in interruptions in their drug therapy reach a point where the therapy no longer reduces their viral loads, even in the absence of any evidence of acquired drug resistance.

25 Apr 2006

Primagen awarded U.S. patent for using mitochondrial DNA quantification as biomarker

Primagen Holding BV has announced that the U.S. Patent and Trademark Office has granted a patent for its Mitox mitochondrial DNA quantification technology as biomarkers for efficacy and adverse events of treatment.

19 Apr 2006