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New report reveals damaging impact of poverty and exploitation on children

The damaging impact of poverty on children and their families and the growing problem of exploitation are revealed in a new report by researchers at the University of East Anglia and University of Warwick.

4 Mar 2020

Novel compounds show promise as potent new treatment for malaria

A novel class of antimalarial compounds that can effectively kill malaria parasites has been developed by Australian and US researchers.

4 Mar 2020

Chemists develop promising molecular tool to target cell immortality's underlying gears

One of the hallmarks of cancer is cell immortality. A Northwestern University organic chemist and his team now have developed a promising molecular tool that targets and inhibits one of cell immortality's underlying gears: the enzyme telomerase.

3 Mar 2020

Novel drug to arrest antibiotic resistance by preventing micro-evolution

Desperate times need desperate measures. Accordingly, scientists, today published a new study in the journal Cell Host and Microbe in March 2020, showing that drugs that prevent the acquisition of DNA-borne antibiotic resistance traits from their surroundings by bacteria can stop mice from becoming resistant to the action of the antibiotics.

3 Mar 2020

Inhibiting energy production in immune T-cells allows some tumors to escape treatment

A small molecule that inhibits energy production in immune T-cells allows some tumors to escape treatment with an immunotherapy called PD-1 blockade therapy, says a study in mice published today in eLife.

3 Mar 2020

Supplying nutritional amino acid restores spatial memory in mouse model of Alzheimer's

Scientists at the Laboratoire des Maladies Neurodégénératives and the Neurocentre Magendie have just shown that a metabolic pathway plays a determining role in Alzheimer's disease's memory problems.

3 Mar 2020

Increasing energy supply within injured spinal cord nerves could help them heal

When the spinal cord is injured, the damaged nerve fibers--called axons--are normally incapable of regrowth, leading to permanent loss of function.

3 Mar 2020

SFU researchers help discover potential new drug to kill superbugs

Researchers in Simon Fraser University's Brinkman Laboratory are collaborating with U.S. researchers to test a new drug that can kill a wide range of superbugs - including some bacteria now resistant to all common antibiotics.

3 Mar 2020

New tool shows potential to predict developmental toxicity in humans with high accuracy

Recently published results from an evaluation of 1,065 chemical and drug substances using the devTOX quickPredict (devTOXqP) screening platform developed by Stemina Biomarker Discovery, Inc. demonstrated the platform's ability to predict developmental toxicity in humans with high accuracy using a cell-based test.

3 Mar 2020

Research could provide more effective way to treat brain swelling after stroke

Cases of potentially deadly brain damage as a result of stroke could be reduced after new research identified a pathway in the brain that causes swelling, and which responds to an innovative treatment.

2 Mar 2020

Drug for Ebola and MERS effective against COVID-19

A new study published in the Journal of Biological Chemistry has revealed that drug Remdesivir could be useful in treating the deadly COVID-19 or the novel coronavirus that is infecting tens of thousands of people across the world.

1 Mar 2020

Michael Hall named winner of 2020 Sjöberg Prize

Michael N. Hall, Ph.D., the National Foundation for Cancer Research's (NFCR) 2017 Szent-Györgyi Prize for Progress in Cancer Research winner, and David Sabatini, M.D., Ph.D., were named winners of the 2020 Sjöberg Prize "for their discovery of the target of rapamycin and the mammalian target of rapamycin, and their roles in the control of cell metabolism and growth."

28 Feb 2020

Scientists reveal ability to reverse Huntington's disease-causing DNA repeat mutations in the lab

Neurodegenerative diseases, like Huntington's disease and myotonic dystrophy, are often referred to as DNA repeat diseases, named because of long repeated sequences in the DNA of patients. Increasing repeat expansion length in the affected tissues contribute to earlier age of disease onset and worsen the progression and severity of the disease over time.

27 Feb 2020

Novel wireless sweat sensor can accurately detect stress levels

If someone asked you right now how stressed you are, what would you say? A little? A lot? You do not know?

26 Feb 2020

McMaster researchers identify antibacterial compound made by cannabis plants

McMaster University researchers have identified an antibacterial compound made by cannabis plants that may serve as a lead for new drug development.

26 Feb 2020

Researchers uncover hidden antibiotic potential of cannabis compound

Public health agencies worldwide have identified antibiotic resistance of disease-causing bacteria as one of humanity's most critical challenges. However, scientists haven't discovered a new class of antibiotics in more than 30 years.

26 Feb 2020

New compound could improve the success rate of photodynamic therapy

PDT does not always kill cells deep within a cancerous tumor, allowing tumors to grow back again.

26 Feb 2020

Novartis and DNDi to partner on development of new oral treatment for visceral leishmaniasis

Novartis and the Drugs for Neglected Diseases initiative, a not-for-profit research and development organization, have signed a collaboration and license agreement to jointly develop LXE408, as a potential new oral treatment for visceral leishmaniasis, one of the world's leading parasitic killers.

25 Feb 2020

Hormone blocker shocker: Drug costs 8 times more when used for kids

Dr. Sudeep Taksali, an orthopedic surgeon, became worried that his 8-year-old daughter had already grown taller than his 12-year-old son. And sometimes she had an attitude more befitting a teenager. Something seemed wrong.

24 Feb 2020

Researchers develop new probe to detect common target of anti-inflammatory drugs

The Chan group at the Beckman Institute for Advanced Science and Technology has recently developed a probe named CoxFluor, which is able to distinguish between Cyclooxygenase-2, an enzyme that plays a major role in driving the progression of cancer, and Cyclooxygenase-1, which is expressed in all cells.

23 Feb 2020