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Tobacco use linked to oral HPV-16

Study participants who reported tobacco use or had higher levels of biomarkers of tobacco exposure had a higher prevalence of the sexually transmitted infection, oral human papillomavirus type 16 (HPV-16), according to a study in the October 8 JAMA, a theme issue on infectious disease.

8 Oct 2014

NF-kB molecule may help malignant cells hide from the immune system

A molecule that helps cancer cells evade programmed self-destruction, an internal source of death, might also help malignant cells hide from the immune system, an external source of death.

8 Oct 2014

Testosterone therapy raises risk of prostate tumors in rats

A researcher who found that testosterone raised the risk of prostate tumors and exacerbated the effects of carcinogenic chemical exposure in rats is urging caution in prescribing testosterone therapy to men who have not been diagnosed with hypogonadism, according to a new study published in the Endocrine Society's journal Endocrinology.

7 Oct 2014

Combination treatment prevents disease progression in patients with advanced melanoma

New data announced today has demonstrated that combinational treatment of cobimetinib with Zelboraf (vemurafenib), the first personalised medicine to extend life in the first-line setting for over 30 years, in patients with advanced melanoma (BRAFV600 mutation-positive) can prevent disease progression (progression-free survival; PFS) by 9.9 months compared to 6.2 months following treatment of vemurafenib alone.

30 Sep 2014

PD-L1 protein could be a potential immunotherapy target for malignant pleural mesothelioma

Treating patients with high-dose radiotherapy after chemotherapy and surgery for malignant pleural mesothelioma does not achieve improvements in local relapse and overall survival, according to data from a prospective randomized phase II trial presented at ESMO 2014 Congress in Madrid.

30 Sep 2014

Chemotherapy, radiotherapy have no negative effect on unborn babies

Children who are exposed to chemotherapy or radiotherapy while in the womb suffer no negative impacts on mental or cardiac development, international studies presented at the ESMO 2014 Congress in Madrid have shown.

29 Sep 2014

Researchers develop new strategy for reducing serious side effects of modern anticancer drugs

An interdisciplinary team of researchers from the University of Vienna (Institute of Inorganic Chemistry) and the Medical University of Vienna (Institute for Cancer Research) has successfully developed a new strategy for reducing the often serious side effects of an important class of modern anticancer drugs (tyrosine kinase inhibitors).

26 Sep 2014

Study findings have potential to advance treatments for small cell lung cell cancer

Two recently published studies by a research team at University Hospitals Case Medical Center Seidman Cancer Center have the potential to advance treatments for small cell lung cell cancer (SCLC). This aggressive form of lung cancer has seen no treatment advances in 30 years and "is a disease in urgent need of new drug therapies," write the study's authors.

26 Sep 2014

Study on widespread vitamin D deficiency among patients who undergo thyroidectomy

A new study from researchers at Henry Ford Hospital in Detroit finds widespread vitamin D deficiency among patients who undergo a thyroidectomy, potentially putting them at greater risk for developing dangerously low blood calcium levels after surgery.

26 Sep 2014

Researchers reveal why RB1 gene mutations primarily cause retinoblastomas in children

Retinoblastoma is a childhood retinal tumor usually affecting children one to two years of age. Although rare, it is the most common malignant tumor of the eye in children.

25 Sep 2014

Patients and healthcare professionals willing to trade false-positive diagnoses, study finds

Both patients and healthcare professionals believe diagnosis of extracolonic malignancy with screening computed tomography (CT) colonography greatly outweighs the potential disadvantages of subsequent radiologic or invasive follow-up tests precipitated by false-positive diagnoses, according to a new study published in the October issue of the journal Radiology.

24 Sep 2014

Seno Medical completes enrollment in PIONEER Pivotal Study of Imagio for diagnosing breast cancer

Seno Medical Instruments, Inc., the company pioneering the development of opto-acoustic technology as a new tool to improve the process of diagnosing breast cancer, announced today it has completed active enrollment of subjects in its U.S.-based PIONEER Pivotal Study of Imagio.

24 Sep 2014

FDG-PET technology less accurate in diagnosing lung cancer in regions where infections are common

A new analysis of published studies found that FDG-PET technology is less accurate in diagnosing lung cancer versus benign disease in regions where infections like histoplasmosis or tuberculosis are common. Misdiagnosis of lung lesions suspicious for cancer could lead to unnecessary tests and surgeries for patients, with additional potential complications and mortality.

24 Sep 2014

Photoacoustics could become alternative to mammography or sonogram for breast cancer detection

One of the lines of research of OILTEBIA, a European science project coordinated by Universidad Carlos III de Madrid, is a method to detect breast cancer based on photoacoustics and which could become an alternative to mammography or sonogram.

22 Sep 2014

Guidelines recommending routine prostate cancer screening for elderly men have minimal effect

The effect of guidelines recommending that elderly men should not be routinely screened for prostate cancer "has been minimal at best," according to a new study led by researchers at Henry Ford Hospital.

22 Sep 2014

Curcumin, cancer-inhibiting peptides show promise in slowing progression of mesothelioma

A common Asian spice and cancer-hampering molecules show promise in slowing the progression of mesothelioma, a cancer of the lung's lining often linked to asbestos. Scientists from Case Western Reserve University and the Georg-Speyer-Haus in Frankfurt, Germany, demonstrate that application of curcumin, a derivative of the spice turmeric, and cancer-inhibiting peptides increase levels of a protein inhibitor known to combat the progression of this cancer.

22 Sep 2014

Study uncovers new genetic risk factor for deadly skin cancer

Buffers that guard against damage to the ends of chromosomes could hold the key to a better understanding of malignant melanoma - the deadliest form of skin cancer - according to new research from the University of Leeds.

18 Sep 2014

ICO-IDIBELL researchers identify 5 genes differentially expressed in colorectal tumors

Researchers at the Catalan Institute of Oncology-Bellvitge Biomedical Research Institute, led by David Garcia-Mollev- have identified 5 genes differentially expressed in normal accompanying cells in colorectal tumors.

17 Sep 2014

EnGeneIC receives award from Cancer Institute NSW for groundbreaking cancer research

EnGeneIC, Ltd., an emerging biopharmaceutical company focused on revolutionizing the treatment of cancer through the targeted delivery of therapeutic agents directly to cancer cells, announced that, together with the Asbestos Disease Research Institute, it has received the 2014 Cancer Institute New South Wales Premier’s Award for Excellence in Translational Cancer Research.

17 Sep 2014

AANS, ASTRO partner to launch national registry for SRS treatments

The American Association of Neurological Surgeons and the American Society for Radiation Oncology are partnering to launch and support a national registry for stereotactic radiosurgery (SRS) treatments.

16 Sep 2014

Malignant News and Research

Tobacco use linked to oral HPV-16

NF-kB molecule may help malignant cells hide from the immune system

Testosterone therapy raises risk of prostate tumors in rats

Combination treatment prevents disease progression in patients with advanced melanoma

PD-L1 protein could be a potential immunotherapy target for malignant pleural mesothelioma

Chemotherapy, radiotherapy have no negative effect on unborn babies

Researchers develop new strategy for reducing serious side effects of modern anticancer drugs

Study findings have potential to advance treatments for small cell lung cell cancer

Study on widespread vitamin D deficiency among patients who undergo thyroidectomy

Researchers reveal why RB1 gene mutations primarily cause retinoblastomas in children

Patients and healthcare professionals willing to trade false-positive diagnoses, study finds

Seno Medical completes enrollment in PIONEER Pivotal Study of Imagio for diagnosing breast cancer

FDG-PET technology less accurate in diagnosing lung cancer in regions where infections are common

Photoacoustics could become alternative to mammography or sonogram for breast cancer detection

Guidelines recommending routine prostate cancer screening for elderly men have minimal effect

Curcumin, cancer-inhibiting peptides show promise in slowing progression of mesothelioma

Study uncovers new genetic risk factor for deadly skin cancer

ICO-IDIBELL researchers identify 5 genes differentially expressed in colorectal tumors

EnGeneIC receives award from Cancer Institute NSW for groundbreaking cancer research

AANS, ASTRO partner to launch national registry for SRS treatments

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