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'Hijacked' cell response to stress reveals potential therapeutic targets for leukemia

A signaling pathway that helps promote normal cell growth worsens a form of leukemia by taking control of another pathway better known for protecting cells from biological stress, a new study shows.

24 Jul 2018

Mysterious molecule Yin Yang may fuel tumor growth in breast cancer

Scientists have unveiled clues about a mysterious molecule called Yin Yang1 - and revealed it may fuel tumor growth in breast cancer.

23 Jul 2018

Imaging study shows how junk DNA activates genes

Researchers at Princeton University have used video imaging to capture the process by which junk DNA activates genes.

23 Jul 2018

New breeding technologies could enhance shape, size, color, and health benefits of produce

Forget vegetables with dull colors and fuzzy skin or fruits that lack of flavor--the produce aisle of the future could offer plant products that are designed for creative cooks and fussy eaters.

20 Jul 2018

Researchers uncover cause for progression of prostate cancer to incurable stage

Researchers at the University of Oulu in Finland have discovered novel genes and mechanisms that can explain how a genomic variant in a single nucleotide polymorphism rs11672691 influences prostate cancer aggressiveness.

20 Jul 2018

Researchers identify enzyme as potential new drug target for blood disorders

Medical researchers have identified a key signaling protein that regulates hemoglobin production in red blood cells, offering a possible target for a future innovative drug to treat sickle cell disease.

20 Jul 2018

Study identifies RNA molecules that regulate male hormones in prostate cancer

In most cases of prostate cancer, tumor cell growth is stimulated by the action of male hormones, or androgens, such as testosterone and dihydrotestosterone.

19 Jul 2018

Researchers identify subtypes of retinal ganglion cells using single-cell RNA sequencing

Single-cell sequencing technologies are filling in fine details in the catalog of life. Researchers at the University of Connecticut Health Center and The Jackson Laboratory have identified 40 subtypes of retinal ganglion cells along with the genetic markers and transcription factors that differentiate them.

19 Jul 2018

High-fat diet and systemic inflammation contribute to progression of prostate cancer

Osaka University-led study shows how a high-fat diet and systemic inflammation contribute to prostate cancer progression

18 Jul 2018

Researchers solve mystery of final blood group system

Ever since the blood type was discovered in 1962, no one has been able to explain why some people become Xga positive while others are Xga negative.

16 Jul 2018

Researchers develop novel approach to bridge gap in cell-free systems

Engineering cellular biology, minus the actual cell, is a growing area of interest in biotechnology and synthetic biology.

13 Jul 2018

Deadlier subtype of metastatic prostate cancer found to be common than previously thought

A new study of prostate cancer in 202 men, whose cancers had spread and were resistant to standard treatment, found that a surprisingly large number of these cancers – about 17 percent – belong to a deadlier subtype of metastatic prostate cancer.

12 Jul 2018

Novel informatics tool helps predict genomic features associated with specific drug responses

The rise of genomics, the shift from considering genes singly to collectively, is adding a new dimension to medical care; biomedical researchers hope to use the information contained in human genomes to make better predictions about individual health, including responses to therapeutic drugs.

12 Jul 2018

Bruker launches innovative iProbe HRMAS for biomolecular, materials and clinical research

At EUROMAR 2018 conference (www.euromar2018.org), Bruker announced the iProbe HRMAS, which now enables full automation of high-resolution magic angle spinning NMR.

From Bruker BioSpin - NMR, EPR and Imaging 10 Jul 2018

Researchers discover critical link in mapping recurrent mutations of melanoma

A critical link in mapping recurrent mutations of melanoma -- the most serious form of skin cancer in humans -- has been discovered by researchers at Washington State University School of Molecular Biosciences, in collaboration with researchers at Georgia State University.

6 Jul 2018

Potential oocyte-specific factors that can drive somatic cell reprogramming

The promise of generating truly pluripotent stem cells from terminally differentiated adult cell types continues to captivate scientists who envision great potential for therapeutic interventions.

4 Jul 2018

Discovery may be key to directly reprogram non-neuronal cells into neurons

It was already in 2012 that a team of scientists headed by Professor Benedikt Berninger first succeeded in reprogramming connective tissue cells present in the brain into neurons.

2 Jul 2018

Timing may be key to evading destruction for bacteria facing antibiotics

For bacteria facing a dose of antibiotics, timing might be the key to evading destruction. In a series of experiments, Princeton researchers found that cells that repaired DNA damaged by antibiotics before resuming growth had a much better chance of surviving treatment.

30 Jun 2018

Scientists focus on critical regulatory protein to find clues on cancer, neurodegenerative diseases

James McNew's and Michael Stern's biochemical hunt for the root cause of a rare, paralyzing genetic disorder is a 10-year quest that's taken an unexpected turn toward everyday killers such as Alzheimer's disease, cancer and aging.

30 Jun 2018

Scientists provide clear picture of mysterious component of the inner ear

A few years ago, Ian Swinburne, HMS research fellow in systems biology, noticed something odd while conducting a time-lapse microscopy study of the inner ear of zebrafish. A tiny structure in the inner ear was pulsing like clockwork, inflating and deflating over and over.

29 Jun 2018

Transcription News and Research

'Hijacked' cell response to stress reveals potential therapeutic targets for leukemia

Mysterious molecule Yin Yang may fuel tumor growth in breast cancer

Imaging study shows how junk DNA activates genes

New breeding technologies could enhance shape, size, color, and health benefits of produce

Researchers uncover cause for progression of prostate cancer to incurable stage

Researchers identify enzyme as potential new drug target for blood disorders

Study identifies RNA molecules that regulate male hormones in prostate cancer

Researchers identify subtypes of retinal ganglion cells using single-cell RNA sequencing

High-fat diet and systemic inflammation contribute to progression of prostate cancer

Researchers solve mystery of final blood group system

Researchers develop novel approach to bridge gap in cell-free systems

Deadlier subtype of metastatic prostate cancer found to be common than previously thought

Novel informatics tool helps predict genomic features associated with specific drug responses

Bruker launches innovative iProbe HRMAS for biomolecular, materials and clinical research

Researchers discover critical link in mapping recurrent mutations of melanoma

Potential oocyte-specific factors that can drive somatic cell reprogramming

Discovery may be key to directly reprogram non-neuronal cells into neurons

Timing may be key to evading destruction for bacteria facing antibiotics

Scientists focus on critical regulatory protein to find clues on cancer, neurodegenerative diseases

Scientists provide clear picture of mysterious component of the inner ear

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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