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EORTC, GIMEMA clinical trial results show high-dose cytarabine improves outcome in AML patients

Results of the EORTC and GIMEMA AML-12 Trial appearing in the Journal of Clinical Oncology show that high-dose cytarabine in induction treatment improves outcome of adult patients with acute myeloid leukemia.

19 Dec 2013

Shared genetic risk for bipolar disorder and BMI

Researchers have found a positive association in the heritability of bipolar disorder and body mass index, supporting the theory that there is some interaction in the genetic mechanisms underlying these two traits.

19 Dec 2013

Hispanic mortality paradox found in RA patients

The so-called “Hispanic survival paradox” has been found to extend to patients with rheumatoid arthritis, whereby Hispanic people with the condition tend have more severe symptoms but equivalent mortality to non-Hispanic White individuals.

19 Dec 2013

Abramson Cancer Center of the University of Pennsylvania celebrates 40th anniversary

This December marks the 40th anniversary of the Abramson Cancer Center of the University of Pennsylvania being designated a Comprehensive Cancer Center by the National Cancer Institute. To celebrate this momentous milestone, over 400 people gathered together early this month for an event recognizing the center's vast achievements in cancer research, patient care, and education during the last four decades.

19 Dec 2013

Computer-controlled, rotating table could deliver high doses of radiotherapy to tumors, spare vulnerable organs

Swivelling patients around on a computer-controlled, rotating table could deliver high doses of radiotherapy to tumours more quickly than current methods, while sparing vulnerable organs such as the heart, brain, eyes and bowel.

19 Dec 2013

New study aims to identify breast cancer patients most susceptible to post-treatment fatigue

Although the prevalence and impact of cancer-related fatigue has been well established, very little is known about its predictors, mechanisms for development, and persistence post-treatment. A new research study at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute, in partnership with UCLA, is aimed at identifying breast cancer patients most susceptible to post-treatment fatigue by measuring biological, behavioral and social risk factors.

19 Dec 2013

Study reveals why people are predisposed to cardiovascular disease and death

A genetic trait known to make some people especially sensitive to stress also appears to be responsible for a 38 percent increased risk of heart attack or death in patients with heart disease, scientists at Duke Medicine report.

19 Dec 2013

People with intermittent explosive disorder elevate levels of markers of systemic inflammation in blood

People with intermittent explosive disorder — a psychiatric illness characterized by impulsivity, hostility and recurrent aggressive outbursts — have elevated levels of two markers of systemic inflammation in their blood, according to a study involving nearly 200 subjects.

19 Dec 2013

TGen, Nemucore, and Barrow collaboration aims for new drugs to treat glioblastoma

The Ben & Catherine Ivy Foundation today announced a $3 million grant to the Translational Genomics Research Institute (TGen), Nemucore Medical Innovations Inc., and Barrow Neurological Institute at St. Joseph's Hospital and Medical Center to help fund significant brain tumor research in Arizona.

18 Dec 2013

UCD Conway Institute researchers identify potential biomarker of idiopathic pulmonary ﬁbrosis

Researchers in UCD Conway Institute have identified a potential biomarker of rapidly progressive pulmonary fibrosis and pinpointed a defective molecular function as a potential therapeutic target.

18 Dec 2013

Octapharma enrolls first patients in GAM-27 Phase II/III clinical trial for relapsing multiple sclerosis

Octapharma AG, one of the largest global manufacturers of human proteins, today announced the enrolment of the first two patients in its GAM-27 Phase II/III clinical trial for the treatment of relapsing multiple sclerosis. Through intravenous administration of immunoglobulin (Octagam 5%), the study seeks to support the overall clinical benefit of a lower annualised relapse rate in patients where first-line treatment is not suitable.

18 Dec 2013

Researchers produce first definitive evidence that MERS-CoV infects camels

Scientists from the Netherlands and Qatar have produced the first definitive evidence that Middle East respiratory syndrome coronavirus infects camels. The researchers used gene-sequencing techniques to show that three camels from a site where two humans contracted MERS-CoV were infected with the virus.

18 Dec 2013

NUS scientists open possible new route for treatment of spinal muscular atrophy

A recent study led by scientists from the National University of Singapore (NUS) opens a possible new route for treatment of Spinal Muscular Atrophy (SMA), a devastating disease that is the most common genetic cause of infant death and also affects young adults.

18 Dec 2013

E. coli evolution studies may lead to better treatments

Going back in time to compare evolutionary changes in several thousand generations of E. coli, a University of Houston biologist hopes to one day be able to isolate a bacterial pathogen and predict the likelihood it will become resistant to a particular antibiotic.

18 Dec 2013

Cedars-Sinai physicians awarded grant to study pregnancy problems resulting from fertility treatments

Two Cedars-Sinai physician-researchers have been awarded grants totaling $4 million from the National Institutes of Health to study how the environment - both in the womb and in the hospital where the baby is born - can affect the newborn and the mother.

18 Dec 2013

UCLA researchers find no evidence of association between iron levels and atherosclerosis risk

A UCLA research team has found no evidence of an association between iron levels in the body and the risk of atherosclerosis, the hardening and narrowing of the arteries that leads to cardiovascular disease, the No. 1 killer in the U.S.

18 Dec 2013

Viewpoints: All eyes on insurers; an employer's perspective on health law; budget peace may not last long

When will the insurers revolt? It's a question that's popping up more and more. On the surface, the question answers itself. We're talking about pinstriped insurance company executives, not Hell's Angels. One doesn't want to paint with too broad a brush, but if you were going to guess which vocations lend themselves least to revolutionary zeal, the actuary sciences rank slightly behind embalmers (Jonah Goldberg, 12/17).

18 Dec 2013

Studies suggest that stress-related disorders may be associated with hippocampal volume loss

Depression has been associated with reduced volume of the hippocampus in magnetic resonance imaging studies in humans. A new study just published in Biological Psychiatry now clarifies the cellular basis of these volumetric changes, which have been unclear until now.

18 Dec 2013

Scientists back ovarian cancer preventative surgery to improve survival

A study by Manchester scientists backs preventative surgery to improve survival for women who are at greater risk of getting ovarian cancer and suggests it appears helpful for women at risk of getting breast cancer because of genetic faults.

18 Dec 2013

Measuring changes in certain proteins may better predict the progression of ALS

Measuring changes in certain proteins -- called biomarkers -- in people with amyotrophic lateral sclerosis may better predict the progression of the disease, according to scientists at Penn State College of Medicine.

17 Dec 2013

Genetic News and Research

EORTC, GIMEMA clinical trial results show high-dose cytarabine improves outcome in AML patients

Shared genetic risk for bipolar disorder and BMI

Hispanic mortality paradox found in RA patients

Abramson Cancer Center of the University of Pennsylvania celebrates 40th anniversary

Computer-controlled, rotating table could deliver high doses of radiotherapy to tumors, spare vulnerable organs

New study aims to identify breast cancer patients most susceptible to post-treatment fatigue

Study reveals why people are predisposed to cardiovascular disease and death

People with intermittent explosive disorder elevate levels of markers of systemic inflammation in blood

TGen, Nemucore, and Barrow collaboration aims for new drugs to treat glioblastoma

UCD Conway Institute researchers identify potential biomarker of idiopathic pulmonary ﬁbrosis

Octapharma enrolls first patients in GAM-27 Phase II/III clinical trial for relapsing multiple sclerosis

Researchers produce first definitive evidence that MERS-CoV infects camels

NUS scientists open possible new route for treatment of spinal muscular atrophy

E. coli evolution studies may lead to better treatments

Cedars-Sinai physicians awarded grant to study pregnancy problems resulting from fertility treatments

UCLA researchers find no evidence of association between iron levels and atherosclerosis risk

Viewpoints: All eyes on insurers; an employer's perspective on health law; budget peace may not last long

Studies suggest that stress-related disorders may be associated with hippocampal volume loss

Scientists back ovarian cancer preventative surgery to improve survival

Measuring changes in certain proteins may better predict the progression of ALS

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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