Protein C News and Research

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Berlin researchers use T cells to target mutations in cancer cells

The efficacy of the immune system to combat disease makes the body's own healing powers a promising approach in the fight against cancer. A Berlin research group led by Wolfgang Uckert, Thomas Blankenstein and Matthias Leisegang has been collaborating with U.S. researcher Hans Schreiber in a project to use immune components called T cells to target mutant proteins produced by cancer cells.

22 Feb 2016

UCLA-led researchers identify specific gene network that promotes repair in peripheral nervous system

Whether or not nerve cells are able to regrow after injury depends on their location in the body. Injured nerve cells in the peripheral nervous system, such as those in the arms and legs, can recover and regrow, at least to some extent. But nerve cells in the central nervous system -- the brain and spinal cord -- can't recover at all.

22 Feb 2016

Calgary researchers develop new class of nanomedicines to treat autoimmune diseases

A new study from the University of Calgary could change the way researchers understand and treat autoimmune diseases such as type 1 diabetes, multiple sclerosis and rheumatoid arthritis.

22 Feb 2016

Dr. Elliot J. Androphy receives IGNITE grant to develop drug candidate for spinal muscular atrophy

Dr. Elliot J. Androphy, the Kampen-Norins Professor and chair of the Department of Dermatology at the Indiana University School of Medicine, has been awarded an IGNITE, or Innovation Grants to Nurture Initial Translational Efforts, grant by the National Institutes of Health.

22 Feb 2016

New molecular delivery system could help ensure delivery of chemotherapy drugs into tumours

Chemotherapy isn't supposed to make your hair fall out -- it's supposed to kill cancer cells. A new molecular delivery system created at U of T Engineering could help ensure that chemotherapy drugs get to their target while minimizing collateral damage.

22 Feb 2016

Australian researchers reveal how nutlins pave way for improving future of cancer treatment

Australian researchers have resolved a mystery about how a promising new class of anti-cancer drugs, called nutlins, work - paving the way for improving the future of cancer treatment.

22 Feb 2016

3-D map of critical protein could lead to new malaria vaccine

A three-dimensional 'map' of a critical protein that malaria parasites use to invade human red blood cells could lead to a vaccine countering the most widespread species of the parasite.

22 Feb 2016

Antibody can give more precise information about Alzheimer's disease than regular radioactive tracers

For the first time, researchers have succeeded in passing an antibody through the blood-brain barrier to act as a tracer for PET imaging of the brain. This resulted in more precise information being obtained than with regular radioactive tracers. The study provides hope for more effective diagnosis of early onset Alzheimer's disease and improvements in monitoring the effects of medication.

22 Feb 2016

BistroMD, Fitness Icon Denise Austin partner to create branded meal-delivery program

BistroMD, the leader in home diet meal delivery, announced a licensing partnership today with Fitness Icon Denise Austin to create a branded meal-delivery program. The program is a natural extension of bistroMD's mission to empower people to lose weight while eating great tasting, nutritious foods, and blends with Denise's healthy lifestyle philosophy.

22 Feb 2016

New approach could open door to more personalized medications for diabetes patients

New research from the University of Copenhagen points to an entirely new approach for designing insulin-based pharmaceuticals. The approach could open the door for more personalized medications with fewer side effects for Type 1 Diabetes patients.

19 Feb 2016

High-fat diet can lead to weight gain and health complications

A new study has revealed following a low-carbohydrate, high-fat diet for just eight weeks can lead to rapid weight gain and health complications.

19 Feb 2016

Stem cell research reveals how Parkinson’s spreads from cell to cell

Stem cell research published today offers up new clues as to how Parkinson’s spreads from cell to cell, a process which has evaded researchers for decades.

19 Feb 2016

DEK gene present in plasma can help predict outcomes for patients with head and neck cancer

Researchers at the University of Cincinnati have discovered that a human cancer-causing gene, called DEK, can be detected in the plasma of head and neck cancer patients. DEK may help doctors understand how a person's immune system could be used to treat cancer or predict outcomes for patients.

18 Feb 2016

Researchers take major step towards developing a cystic fibrosis drug

Researchers from Eindhoven University of Technology and McGill University in Montreal (Canada) have taken an important step towards developing a drug against cystic fibrosis.

18 Feb 2016

Revealing dynamic protein complexes with NMR: an interview with Elisar Barbar

Most proteins are involved in interactions with one or a few functional ligands, but some proteins, like light chain 8 (LC8), have numerous binding partners. LC8 interacts with more than 100 functionally different proteins, from viral proteins to motor proteins to proteins involved in cell division.

From Bruker BioSpin Group 18 Feb 2016

Discovery could lead to more effective vaccines, personalised therapies for TB

Tuberculosis (TB) used to kill one in seven people around the world before the advent of antibiotics. However the increasing prevalence of multi-drug resistant TB means that doctors are running out of options in trying to combat this bacterium.

18 Feb 2016

Study explores link between CSF biomarkers and cognition in Parkinson's disease

Many patients with Parkinson's Disease (PD) develop mild cognitive impairment (MCI) or dementia. Identifying biomarkers for cognitive impairment could be instrumental in facilitating both early diagnosis of MCI and developing new cognitive-enhancing treatments. New research published in the Journal of Parkinson's Disease indicates that lower concentrations of α-synuclein in cerebrospinal fluid (CSF) is associated with reduced performance on several cognitive tests.

18 Feb 2016

African Americans with common genetic variants at increased risk for blood clots

New research published online today in Blood, the Journal of the American Society of Hematology (ASH), identifies common genetic variants predominantly found in African Americans that double their risk for blood clots.

18 Feb 2016

New drug combination shows promise for patients with non-small cell lung cancer

Lung cancer is the most common cause of cancer-related death in the United States resulting in more than 158,000 deaths each year. With a 5-year survival rate at only 18 percent, the development of new and improved treatment options is needed.

18 Feb 2016

Study may lead to potential drug targets for tumor formation in pulmonary tuberous sclerosis complex

In a new study published in the American Association of Cancer Research's journal Cancer Research, a pair of investigators at Rutgers and Columbia universities has identified a gene that may provide a new source of potential drug targets for tumors that arise in pulmonary tuberous sclerosis complex (TSC).

18 Feb 2016

Protein C News and Research

Berlin researchers use T cells to target mutations in cancer cells

UCLA-led researchers identify specific gene network that promotes repair in peripheral nervous system

Calgary researchers develop new class of nanomedicines to treat autoimmune diseases

Dr. Elliot J. Androphy receives IGNITE grant to develop drug candidate for spinal muscular atrophy

New molecular delivery system could help ensure delivery of chemotherapy drugs into tumours

Australian researchers reveal how nutlins pave way for improving future of cancer treatment

3-D map of critical protein could lead to new malaria vaccine

Antibody can give more precise information about Alzheimer's disease than regular radioactive tracers

BistroMD, Fitness Icon Denise Austin partner to create branded meal-delivery program

New approach could open door to more personalized medications for diabetes patients

High-fat diet can lead to weight gain and health complications

Stem cell research reveals how Parkinson’s spreads from cell to cell

DEK gene present in plasma can help predict outcomes for patients with head and neck cancer

Researchers take major step towards developing a cystic fibrosis drug

Revealing dynamic protein complexes with NMR: an interview with Elisar Barbar

Discovery could lead to more effective vaccines, personalised therapies for TB

Study explores link between CSF biomarkers and cognition in Parkinson's disease

African Americans with common genetic variants at increased risk for blood clots

New drug combination shows promise for patients with non-small cell lung cancer

Study may lead to potential drug targets for tumor formation in pulmonary tuberous sclerosis complex

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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