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New gene therapy approach to treating DMD reduces symptoms, extends life span in mouse model

A gene therapy approach to treating the progressive muscle wasting disorder Duchenne muscular dystrophy (DMD) that does not replace the mutated DMD gene but instead delivers the gene for ITGA7, a protein in skeletal muscle, led to reduced symptoms and significantly extended life span in a mouse model of severe DMD. Over-expression of ITGA7 did not elicit an immune reaction, further supporting its potential as a novel treatment for DMD, according to a new study published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

30 Sep 2015

Utah researchers awarded NIH grant to develop informatics platform to identify cause of pediatric asthma

For many doctors, figuring out what caused a kid's asthma attack means opening up regional air quality databases and applying a lot of guesswork.

30 Sep 2015

Risks of developing type 2 diabetes for South Asians begin immediately at birth

New research suggests that the risks of developing type 2 diabetes for South Asians - a group long known to suffer from substantially higher rates of both diabetes and heart disease—begins immediately at birth.

30 Sep 2015

New report implicates five genetic regions that play major roles in CF disease severity

If you have two faulty copies of the CFTR gene, you will have cystic fibrosis. But the severity of your disease will depend on environmental factors and many other genes. Locating these genes and altering their function could lead to new therapies.

29 Sep 2015

Current fetal growth standards do not consider racial and ethnic differences

Current standards for ultrasound evaluation of fetal growth may lead to misclassification of up to 15 percent of fetuses of minority mothers as being too small, according to a study by researchers at the National Institutes of Health (NIH) and other institutions.

29 Sep 2015

Study demonstrate similarities in language acquisition between signed and spoken languages

A spoken language is more than just words and sounds. Speakers use changes in pitch and rhythm, known as prosody, to provide emphasis, show emotion, and otherwise add meaning to what they say.

29 Sep 2015

Researchers suggest potential method of screening for jaundice in preterm infants

A research group led by Kobe University Graduate School of Medicine Project Professor MORIOKA Ichirou and Professor IIJIMA Kazumoto (Department of Pediatrics) has suggested a potential method of screening for jaundice (hyperbilirubinemia), a cause of cerebral palsy and loss of hearing in preterm infants with kyperbilirubinemia, using painless dermal monitoring.

29 Sep 2015

Majority of cancer patients lack access to safe, affordable surgical care

Over 80% of the 15 million people diagnosed with cancer worldwide in 2015 will need surgery, but less than a quarter will have access to proper, safe, affordable surgical care when they need it, according to a major new Commission examining the state of global cancer surgery, published in The Lancet Oncology, and being presented at the 2015 European Cancer Congress in Vienna, Austria.

29 Sep 2015

Researchers develop strategies to prevent pediatric head injuries from toppled TV sets

Researchers from the University of Toronto and St. Michael's Hospital (Toronto, Ontario, Canada) reviewed medical articles describing head injuries caused by toppled television sets in children 0 to 18 years of age. These injuries, which can be severe and sometimes fatal in small children, are often unwitnessed by adult caregivers, indicating a lack of awareness of the dangers posed to toddlers by TV sets that are not securely mounted.

29 Sep 2015

Breakthrough research to be presented at AAO-HNSF 2015 Annual Meeting & OTO EXPO

Research to be presented tomorrow at the 2015 Annual Meeting & OTO EXPOSM of the American Academy of Otolaryngology--Head and Neck Surgery Foundation (AAO-HNSF) spans across the otolaryngology specialty.

29 Sep 2015

Cancer treatment does not affect pregnancy outcome, shows new study

Women who are pregnant when diagnosed with cancer can start treatment for their disease immediately and do not need to terminate their pregnancy due to worries over the effects of therapy on the development of their child.

29 Sep 2015

Polio no more in Nigeria, WHO says

The World Health Organization announced today that polio is no longer endemic in Nigeria. This is the first time that Nigeria has interrupted transmission of wild poliovirus, bringing the country and the African region closer than ever to being certified polio-free.

29 Sep 2015

Expectant mothers can modify genetic information of their future child, shows new research

A new scientific discovery confirms for the first time that mothers-to-be are capable of modifying the genetics of their future child, even when the egg has been donated.

29 Sep 2015

Admission hematocrit helps predict pediatric patients at increased risk of bleeding after injury

A team of researchers from the Trauma Program at Children's Hospital Los Angeles conclude that an admission hematocrit provides a reliable screening test for identifying pediatric patients who are at an increased risk of bleeding after injury.

29 Sep 2015

New study broadens understanding of how the immune system responds to flu virus

A new study of influenza infection in an animal model broadens understanding of how the immune system responds to flu virus, showing that the process is more dynamic than usually described, engaging a broader array of biological pathways. The researchers say their findings may offer key insights for designing more effective vaccines in general.

29 Sep 2015

Low birth weight associated with low levels of social trust in adulthood

How much does your baby weigh? All new parents are familiar with that question. Perhaps their reply is more important than we realize. Birth weight affects how much trust an individual will have in other people in his adult life. Trust, in turn, is the glue that prevents society from falling apart. This phenomenon is at the center of new research from Aarhus School of Business and Social Sciences (Aarhus BSS) at Aarhus University, Denmark.

29 Sep 2015

Bariatric surgery results in substantial weight loss in overweight children with Prader-Willi syndrome

Obesity is a leading cause of complications and death in children suffering from Prader-Willi syndrome (PWS), yet there are few effective treatment options for these patients. In a new study published in Surgery for Obesity and Related Disease researchers found that bariatric surgery, specifically laparoscopic sleeve gastrectomy (LSG), resulted in substantial weight loss with no apparent adverse effect on growth in a small group of severely overweight patients with PWS.

29 Sep 2015

Endocrine-disrupting chemical exposure linked to increased risk of diabetes and obesity

Emerging evidence ties endocrine-disrupting chemical exposure to two of the biggest public health threats facing society - diabetes and obesity, according to the executive summary of an upcoming Scientific Statement issued today by the Endocrine Society.

29 Sep 2015

NIH's Human Placenta Project aims to revolutionize understanding of the placenta

The National Institutes of Health has announced $46 million in research awards for the Human Placenta Project, an initiative to revolutionize understanding of the placenta. The awards will fund technology development and testing to assess placental function throughout pregnancy, with the ultimate goal of improving pregnancy outcomes and lifelong health.

29 Sep 2015

ADHD children and their mothers more likely to have shorter telomeres, say Brazilian scientists

Psychiatric disorders like Attention Deficit Hyperactive Disorder (ADHD) impact family's emotions and social life. It is well known. What is new is that this condition also affects the DNA of patients and their parents.

28 Sep 2015

Children News and Research

New gene therapy approach to treating DMD reduces symptoms, extends life span in mouse model

Utah researchers awarded NIH grant to develop informatics platform to identify cause of pediatric asthma

Risks of developing type 2 diabetes for South Asians begin immediately at birth

New report implicates five genetic regions that play major roles in CF disease severity

Current fetal growth standards do not consider racial and ethnic differences

Study demonstrate similarities in language acquisition between signed and spoken languages

Researchers suggest potential method of screening for jaundice in preterm infants

Majority of cancer patients lack access to safe, affordable surgical care

Researchers develop strategies to prevent pediatric head injuries from toppled TV sets

Breakthrough research to be presented at AAO-HNSF 2015 Annual Meeting & OTO EXPO

Cancer treatment does not affect pregnancy outcome, shows new study

Polio no more in Nigeria, WHO says

Expectant mothers can modify genetic information of their future child, shows new research

Admission hematocrit helps predict pediatric patients at increased risk of bleeding after injury

New study broadens understanding of how the immune system responds to flu virus

Low birth weight associated with low levels of social trust in adulthood

Bariatric surgery results in substantial weight loss in overweight children with Prader-Willi syndrome

Endocrine-disrupting chemical exposure linked to increased risk of diabetes and obesity

NIH's Human Placenta Project aims to revolutionize understanding of the placenta

ADHD children and their mothers more likely to have shorter telomeres, say Brazilian scientists

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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