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Certain viral infections during pregnancy could cause behavioral changes in offspring

A study published in the journal Science found that activation in pregnant mice of a particular immune response, similar to what may occur with certain viral infections during pregnancy, alters the brain structure of the mouse offspring and causes behavioral changes, reminiscent of those observed in humans with autism spectrum disorder (ASD).

30 Jan 2016

TSRI scientists reveal workings of key 'relief-valve' in cells

A team led by scientists at The Scripps Research Institute has solved a long-standing mystery in cell biology by showing essentially how a key "relief-valve" in cells does its job.

30 Jan 2016

Researchers discover previously unknown mechanism that regulates neurogenesis

Bassem Hassan's team at VIB/KU Leuven has discovered a previously unknown mechanism that is highly conserved between species and which regulates neurogenesis through precise temporal control of the activity of a family of proteins essential for brain development: the proneural proteins.

30 Jan 2016

Two studies shed new light on nature of tandem DNA repeat arrays

A pair of studies by a team of scientists has shed new light on the nature of a particular type of DNA sequences—tandem DNA repeat arrays—that play important roles in transcription control, genome organization, and development.

29 Jan 2016

Adhering to certain diet may help postpone need for dialysis in CKD patients

Adhering to a certain diet may help postpone the need for dialysis in patients with chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

29 Jan 2016

UCLA researchers find protein combination that could improve clinical bone restoration

A UCLA research team has found a combination of proteins that could significantly improve clinical bone restoration. The findings may be a big step toward developing effective therapeutic treatments for bone skeletal defects, bone loss and osteoporosis.

29 Jan 2016

New treatment could stop progression of ALS

Researchers at Oregon State University announced today that they have essentially stopped the progression of amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, for nearly two years in one type of mouse model used to study the disease - allowing the mice to approach their normal lifespan.

29 Jan 2016

Scientists trace one of the causes of ischemia renal failure

Every year acute renal failure affects over 13 million people and leads to 1.7 million deaths across the globe. It often develops when an insufficient supply of oxygen reaches the kidneys, a condition called ischemia.

29 Jan 2016

Researchers find how microtubules, motor proteins assemble into macroscopic networks

What bones are to bodies, the cytoskeleton is to cells. The cytoskeleton maintains cellular structure, builds appendages like flagella and, together with motor proteins, powers cellular movement, transport, and division. Microtubules are a critical component of the cytoskeleton, vital for cell division and, because of that, an excellent target for chemotherapy drugs.

29 Jan 2016

Mutation or amplification of HER2 gene may lead to lung cancer

A joint study by University of Colorado Cancer Center and Memorial Sloan Kettering Cancer Center published in the Journal of Thoracic Oncology shows two distinct causes of HER2 activation in lung cancer: mutation of the gene and amplification of the gene.

29 Jan 2016

New prognostic biomarker may help determine risk of prostate cancer-related death

Researchers at the University of Copenhagen have identified a new prognostic biomarker: the neuropeptide pro-NPY, which may help determine the risk of dying from prostate cancer. This particular type of protein is very specific to prostate cancer cells and could help identify whether newly diagnosed patients require radical prostatectomy surgery or if it is safe to delay surgery.

28 Jan 2016

Brain-derived neurotrophic factor linked to slower cognitive decline in older people

Older people with higher amounts of a key protein in their brains also had slower decline in their memory and thinking abilities than people with lower amounts of protein from the gene called brain-derived neurotrophic factor, or BDNF, according to a study published in the January 27, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Jan 2016

Stopping disruptions in cellular 'trash removal' may guard against neurodegenerative diseases

Stopping disruptions in cellular "trash removal" brought on by errors in molecular marks on DNA may guard against neurodegenerative diseases like Parkinson's.

27 Jan 2016

Synaptic plasticity alterations responsible for memory impairment in Alzheimer's disease

Neurons communicate with one another by synaptic connections, where information is exchanged from one neuron to its neighbor. These connections are not static, but are continuously modulated in response to the ongoing activity (or experience) of the neuron. This process, known as synaptic plasticity, is a fundamental mechanism for learning and memory in humans as in all animals.

27 Jan 2016

University of Leicester researchers publish structural details of protein linked to many types of cancer

A team from the University of Leicester has for the first time published a detailed description of a protein linked to many types of cancer.

27 Jan 2016

Study identifies potential therapeutic targets for treatment of multiple sclerosis

Treatment of multiple sclerosis (MS) and other inflammatory diseases may benefit by new findings from a study that identified potential therapeutic targets for a devastating disease striking some 2.3 million people worldwide.

26 Jan 2016

Using Single-Molecule Studies to Understand Cellular Processes: An Interview with Professor W. E. Moerner

Single fluorescent molecules provide a local nanometer-sized probe of complex systems. We can measure the motion of the single molecule, use them to achieve imaging on a scale down to 20 nanometers, or we can infer aspects of the behaviour of the object under study by the details of the light that is emitted.

From Pittcon 26 Jan 2016

Preventing memory loss in Alzheimer's Disease, a new key mechanism

26 Jan 2016

New study aims to prevent chronic cardiac failure

Researchers at Osaka University clarified that the cell adhesion inhibition of periostin1 damages myocardinal cells, inducing compromised cardiac myocyte contractile force and myocytes death, leading to the onset of cardiac failure after AMI through the administration of periostin neutralizing antibodies they had developed on their own.

26 Jan 2016

Simple blood test could help predict emergence of pre-eclampsia in pregnant women

Pre-eclampsia is a serious illness associated with pregnancy, which develops after twenty weeks and is associated with defective ingrowing of the placenta within the mother. The dangerous illness is both the second most frequent cause of death in pregnant women, and the reason for severe complications for mother and child, especially during premature births.

25 Jan 2016

Protein C News and Research

Certain viral infections during pregnancy could cause behavioral changes in offspring

TSRI scientists reveal workings of key 'relief-valve' in cells

Researchers discover previously unknown mechanism that regulates neurogenesis

Two studies shed new light on nature of tandem DNA repeat arrays

Adhering to certain diet may help postpone need for dialysis in CKD patients

UCLA researchers find protein combination that could improve clinical bone restoration

New treatment could stop progression of ALS

Scientists trace one of the causes of ischemia renal failure

Researchers find how microtubules, motor proteins assemble into macroscopic networks

Mutation or amplification of HER2 gene may lead to lung cancer

New prognostic biomarker may help determine risk of prostate cancer-related death

Brain-derived neurotrophic factor linked to slower cognitive decline in older people

Stopping disruptions in cellular 'trash removal' may guard against neurodegenerative diseases

Synaptic plasticity alterations responsible for memory impairment in Alzheimer's disease

University of Leicester researchers publish structural details of protein linked to many types of cancer

Study identifies potential therapeutic targets for treatment of multiple sclerosis

Using Single-Molecule Studies to Understand Cellular Processes: An Interview with Professor W. E. Moerner

Preventing memory loss in Alzheimer's Disease, a new key mechanism

New study aims to prevent chronic cardiac failure

Simple blood test could help predict emergence of pre-eclampsia in pregnant women

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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