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What are the present challenges and future considerations in developing vaccines against mucosal respiratory viruses?

In a recent review, the former director of the National Institute of Allergy and Infectious Diseases and former chief medical advisor to the president of the United States (U.S.), Dr. Fauci, and his team review the roadblocks to developing effective vaccines against viruses that infect the human respiratory mucosa and discuss strategies for next-generation vaccine development against mucosal respiratory viruses

13 Jan 2023

Altering a cellular process can lead stem cells to die or regenerate, study finds

A new study led by Cedars-Sinai and the University of California, San Francisco (UCSF), has determined that altering a cellular process can lead stem cells - cells from which other cells in the body develop - to die or regenerate.

13 Jan 2023

Researchers explore why card games are the most entertaining and addictive

A jerk is a physical quantity that represents a sudden change of acceleration. It is widely used as a parameter in engineering, manufacturing, sports science, and other industries.

13 Jan 2023

Researchers study bacterial co-infections and antibiotic use in COVID-19 patients

Researchers estimated the frequency of bacterial co-infections among hospitalized coronavirus disease 2019 (COVID-19) patients and of antibiotic prescriptions in the initial COVID-19 period for appraising the usage of antibiotic stewardship criteria.

13 Jan 2023

Antivenom could prevent the appearance of necrotic skin lesion after brown recluse spider bites

One of the most dreaded effects of the bite of the brown recluse spider (Loxosceles spp) is the appearance of a necrotic skin lesion, but a clinical study by Brazilian researchers recently reported in PLOS Neglected Tropical Diseases shows that the problem can be solved by administering antivenom, especially if this is done within 48 hours of the incident.

11 Jan 2023

Study suggests a link between the protein-coding gene TREM2 and obesity in females

A recent Scientific Reports study has investigated the link between TREM2 expression and human obesity, based on two large public datasets, namely, the UK Biobank (UKB) and the Genotype-Tissue Expression (GTEx) project.

11 Jan 2023

Green tea may protect against telomere shortening due to biological aging

A new study in Scientific Reports aimed to analyze the association between cross-section and longitudinal LTL changes with the consumption of soft drinks, coffee, and tea among middle-aged and older Korean men and women for six years. It also assessed any changes in the association results according to a difference in sex and age groups.

11 Jan 2023

Rethinking next generation of improved vaccines for mucosa-replicating viruses

Vaccines that provide long-lasting protection against influenza, coronaviruses and respiratory syncytial virus (RSV) have proved exceptionally difficult to develop.

11 Jan 2023

Waning immunity hypothesis may explain mumps resurgence in the United States

Researchers investigated the putative mechanism(s) of vaccine failure underlying the resurgence of mumps in the United States (US).

11 Jan 2023

Three genes found to be directly associated with cleft lip and palate

Researchers are finding more genes directly associated with cleft lip and palate.

11 Jan 2023

The main source of editing of the mpox virus genome during the 2022 outbreak

Researchers investigated the main source of editing of the 2022 mpox virus genome.

11 Jan 2023

Study suggests many symptoms are more common after COVID-19 infection, but only a few are commonly associated with a long COVID diagnosis

Researchers compared symptoms in patients with and without prior COVID-19 history and investigated symptoms associated with long COVID diagnosis in the UK.

11 Jan 2023

MIS-C more common and severe than previously thought

In a recent study published in the JAMA Network Open journal, researchers compared the characteristics of multisystem inflammatory syndrome in children (MIS-C) and coronavirus disease 2019 (COVID-19).

10 Jan 2023

Men who lack interest in sex are at heightened risk of premature death

A recent study published in the journal PLOS ONE evaluated the association between sexual interest and mortality.

10 Jan 2023

Certain type of glial cell plays a major role in spatial learning

There are two fundamentally different cell types in the brain, neurons and glial cells. The latter, for example, insulate the "wiring" of nerve cells or guarantee optimal working conditions for them.

10 Jan 2023

Circadian clock can preserve fitness even under long-term nutritional stress

Cells with a functioning molecular clock are better able to adapt to changes in glucose supply and can recover faster from long-term starvation, according to a study published today in eLife.

10 Jan 2023

Older adults with greater severity of hearing loss more likely to have dementia, study finds

A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health found that older adults with greater severity of hearing loss were more likely to have dementia, but the likelihood of dementia was lower among hearing aid users compared to non-users.

10 Jan 2023

Genomic analysis of mpox virus genomes reveal multiple lineages with human-to-human transmissibility

Researchers from Nigeria and the United Kingdom (U.K.) analyzed mpox virus genomes and found that divergent lineages of the mpox virus exhibiting human-to-human transmission existed in the Nigerian population before the 2022 spread of the virus outside of the endemic regions.

10 Jan 2023

How does early life diet affect a child's mental health and personality?

A recent Nutrients study investigated the relationship between maternal and child diet and a child's personality traits and mental health, i.e., depression and anxiety.

10 Jan 2023

Deletions in the antigenic regions in SARS-CoV-2 increase transmission and immune evasion ability

A recent study published in the journal Scientific Reports examined the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) whole genome data to determine the deletion mutations around the spike protein region associated with increased transmission of the virus and identified an increase in the deletion-prone spike protein regions indicating an evolution strategy for immune escape.

9 Jan 2023

Frequency News and Research

What are the present challenges and future considerations in developing vaccines against mucosal respiratory viruses?

Altering a cellular process can lead stem cells to die or regenerate, study finds

Researchers explore why card games are the most entertaining and addictive

Researchers study bacterial co-infections and antibiotic use in COVID-19 patients

Antivenom could prevent the appearance of necrotic skin lesion after brown recluse spider bites

Study suggests a link between the protein-coding gene TREM2 and obesity in females

Green tea may protect against telomere shortening due to biological aging

Rethinking next generation of improved vaccines for mucosa-replicating viruses

Waning immunity hypothesis may explain mumps resurgence in the United States

Three genes found to be directly associated with cleft lip and palate

The main source of editing of the mpox virus genome during the 2022 outbreak

Study suggests many symptoms are more common after COVID-19 infection, but only a few are commonly associated with a long COVID diagnosis

MIS-C more common and severe than previously thought

Men who lack interest in sex are at heightened risk of premature death

Certain type of glial cell plays a major role in spatial learning

Circadian clock can preserve fitness even under long-term nutritional stress

Older adults with greater severity of hearing loss more likely to have dementia, study finds

Genomic analysis of mpox virus genomes reveal multiple lineages with human-to-human transmissibility

How does early life diet affect a child's mental health and personality?

Deletions in the antigenic regions in SARS-CoV-2 increase transmission and immune evasion ability

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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